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Ing. Václav Klika, Ph.D.

Phone +420 266 053 294 E-mail klika@it.cas.cz Room M7204 Department Department D 2 - Thermodynamics Position researcher Research area mathematical modelling, non-equilibrium thermodynamics, tissue remodelling, applied mathematics, mixture theory Personal webpage
Curriculum vitae
currently Assistant professor at Dept. of Mathematics, FNSPE, CTU in Prague
since 2004: Institute of Thermomechanics ASCR, v. v. i. (part-time)

Education
2006-2009: Ph.D. student at CTU FNSPE in Prague, research project „Mathematical models of tissue remodelling“
2006: Eng., CTU FNSPE in Prague, research project „Mathematical model of bone remodelling“

Stays abroad
2005 (1 months): laboratories of Ecole Polytechnique, Université du Montreal, Canada
2010 (2 months): Research Group on Structural Mechanics and Materials Modeling (GEMM), Aragón Institute of Engineering Research (I3A), University of Zaragoza; aim: formulation of new bone remodelling model by merging our two distinct approaches;
2010 (3 months): Oxford Centre for Collaborative and Applied Mathematics, Mathematical Institute, University of Oxford (Visiting Postdoctoral Research Assistantships), scope: mathematical biology (RD models), fi nding intrinsic slow manifold of complex models, theory of growth and mixture theory
2011 (1 month): Oxford Centre for Collaborative and Applied Mathematics, Mathematical Institute, University of Oxford (Short-term visitor)
2012 (2 months): Dagmar Iber BSSE, ETH, Switzerland; obdržel EMBO short-term fellowship award

View author's publications in the ASCR database
Selected publications
Klika, V., Baker, R.E., Headon, D., Gaff ney, E.A. 2012. The influence of receptor-mediated interactions on reaction-diff usion mechanisms of cellular self-organisation. Bull Math Biol, 74(4): 935-957.

Myslivec, R., Klika, V., Zemkova, D., Marikova, A., Marik, I. Prediction of suitable time instant for external xation removal in distraction osteogenesis according to a simple biomechanical model. Locomotor system, 3+4, 328-333.

Klika, V., 2011. Computer simulation of tissue remodelling [a review in Czech]. Cs cas fyz, 5, 272-277.

Klika, V., Maršík, F., 2011. Feasible predictions of bone remodelling using modelling techniques . Locomotor system, 1+2, 26-41.

editor of  Biomechanics in Applications and Theoretical Biomechanics by InTech, Vienna; August, Novem-
ber 2011, ISBN 978-953-307-312-5 and 978-953-307-969-1.

Klika, V, Maršík, F, July 2011. Biomechanics, vol 1. Ed. Klika V, IN-TECH, Vienna, Ch. Feasible simulation of diseases related to bone remodelling and of their treatment. ISBN 978-953-307-312-5, [online] http://www.sciyo.com

Klika, V. 2010. Comparison of the Effects of Possible Mechanical Stimuli on the Rate of Biochemical Reactions. Journal of Physical Chemistry B. 114(32), 10567-10572

Klika, V., Maršík, F., 2010. A Thermodynamic Model of Bone Remodelling: The Influence of Dynamic Loading Together with Biochemical Control. Journal of Musculoskeletal and Neuronal Interactions, 10(3), 210-220.

Klika, V., Maršík, F., 2009. Coupling effect between mechanical loading and chemical reactions. Journal of Physical Chemistry B 113, 14689-14697.

Klika, V., Maršík, F., Mařík, I., February 2010. Dynamic Modelling. IN-TECH, Vienna, Ch. Influencing the Effect of Treatment of Disease Related to Bone Remodelling by Dynamic Loading, ISBN 978-953-7619-68-8, [online] http://www.sciyo.com

Bougherara, H., Klika, V., Maršík, F., Mařík, I., Yahia, L., 2009. A new predictive model for monitoring bone remodeling. Journal of Biomedical Materials Research: Part A, 95(1), 9-24.

Maršík, F., Klika, V. , Chlup, H., 2010. Remodelling of living bone induced by dynamic loading and drugs delivery—Numerical modelling and clinical treatment, Math. Comput. Simul. 80, 1278-1288.

Bougherara, H., Klika, V., Maršík, F., Mařík, I., Yahia, L., 2009. Damage and Fracture Mechanics. Springer Netherlands, Ch. A Novel Approach for Bone Remodeling After Prosthetic Implantation, pp. 553--565, ISBN 978-90-481-2668-2.

Klika, V., Marsik, F., Landor, I., August 2008. Longterm prediction of bone remodelling effect around implant. In: XXII International Congress of Theoretical and Applied Mechanics, Adelaide, Astralia, Abstracts book, Edited by J. Denier, M. Finn and T. Mattner. CD-ROM proceedings, ISBN 978-0-9805142-1-6, http://ictam2008.adelaide.edu.au

Maršík, F ; Filová, E ; Klika, V. ; Amler, E. Thermodynamic analysis of chondrocyte proliferation on different scaffolds. In 2nd International Symposium on Biothermodynamics. Frankfurt a M: Dechema e.V, 2008. S. 58-58.

Klika, V., Maršík, F., and Landor, I., 2007. Bone remodeling after hip joint replacement. Numerical modeling and comparism with clinical observation. Locomotor system - Supplementum 14, 340-343.
Teaching
Lecturer of mathematical methods in biology and medicine na katedře matematiky FJFI ČVUT v Praze
Seminar tutor of Equations of mathematical physics at dept. of mathematics of FNSPE, Czech Technical University in Prague
Seminar tutor of Linear algebra at dept. of mathematics of FNSPE, Czech Technical University in Prague
Seminar tutor of Mathematical analysis at dept. of mathematics of FNSPE, Czech Technical University in Prague
Seminar mathematical analysis revisited on dept. of mathematics of FNSPE, Czech Technical University in Prague

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