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Education |
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1990-1995 |
Ph.D. in Biochemistry, Institute of Molecular Genetics, Academy of Sciences of the Czech Republic, Prague. |
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1981-1986 |
M.Sc. (Mgr.) in Inorganic Chemistry (specialization: X-ray structural analysis), Department of Inorganic Chemistry, Faculty of Sciences, Charles University, Prague. |
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Experience |
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1997 (3 months) |
Postdoctoral fellow at ESRF Grenoble, ID 2 - High Brilliance Beam line (protein crystallography), Grenoble, Switzerland. |
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1995-1996 |
Postdoctoral fellow at Laboratory of Structural Immunology, Institute Pasteur, Paris, France. |
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1994 (3 months) |
Short-term fellowship at Laboratory of Structural Immunology, Institute Pasteur, Paris, France. |
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Appointments |
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since 2008 |
Scientist, Structural biology research-service team, Institute of Organic Chemistry and Biochemistry v.v.i., Academy of Sciences of the Czech Republic, Prague. |
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1998-2008 |
Scientist, Department of Gene Manipulations, Institute of Molecular Genetics, Academy of Sciences of the Czech Republic, Prague. |
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1986-1989 |
Research assistant (X ray structure analysis of polycrystalic graphite like carbon materials), Institute of Geology, Czechoslovak Academy of Sciences, Prague. |
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Teaching |
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2003-2008 |
Determination of 3-D structures of macromolecules course: Department of Biochemistry, Faculty of Natural Sciences, Charles University, Prague. |
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2002-2008 |
Determination of 3-D structures of macromolecules course (part of Bioinformatics II lectures): Institute of Physical Biology, University of South Bohemia, České Budějovice. |
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2001, 2002, 2003, 2005 |
Teaching at practical courses Crystallization course (CC2001, CC2002 and CC2003, CC2005): University and Academic Center Nové Hrady, Czech Republic. |
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2004, 2006, 2008 |
Teaching at FEBS advanced courses: Advanced methods in protein crystallization, University and Academic Center Nové Hrady, Czech Republic. |
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Research interest |
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Protein crystallography, phase problem, HIV protease, structure-assisted drug design, antibody fragments, metabolism of purines and pirimidines. |
