Marhavý P., Bielach A., Abas M., Abuzeineh A., Duclercq J., Tanaka H., Pařezová M., Petrášek J., Friml J., Kleine-Vehn J., Benková E.
DEVELOPMENTAL CELL
21:
796-804,
2011
Klíčová slova:
cytokinin, auxin, PIN, vacuole
Abstrakt:
Cytokinin is an important regulator of plant growth and development. In Arabidopsis thaliana, the two component phosphorelay mediated through a family of histidine kinases and response regulators is recognized as the principal cytokinin signal transduction mechanism activating the complex transcriptional
response to control various developmental processes. Here, we identified an alternative mode
of cytokinin action that uses endocytic trafficking as a means to direct plant organogenesis. This activity
occurs downstream of known cytokinin receptors but through a branch of the cytokinin signaling
pathway that does not involve transcriptional regulation. We show that cytokinin regulates endocytic
recycling of the auxin efflux carrier PINFORMED1 (PIN1) by redirecting it for lytic degradation in vacuoles.
Stimulation of the lytic PIN1 degradation is not a default effect for general downregulation of proteins
from plasma membranes, but a specific mechanism to rapidly modulate the auxin distribution in
cytokinin-mediated developmental processes.
Autoři z ÚEB: Markéta Pařezová,
Jan Petrášek
Čeština
English