| |
| Education |
| 1998-2006 |
Ph.D. in organic chemistry, under supervision of Prof. O. Paleta at Department of Organic Chemistry,
Faculty of Chemical Technology, Institute of Chemical Technology, Prague. Thesis: Study of Syntheses of Some 3-Fluorofuran-2(5H)-ones. |
| 1992-1998 |
Ing. (equivalent of M.Sc.) in organic chemistry, under supervision of Prof. O. Paleta at Department of Organic Chemistry,
Faculty of Chemical Technology, Institute of Chemical Technology, Prague. Diploma thesis: Syntheses of Some 2-Fluoro-2-buten-4-olides from 2-Hydroxyketones. |
| |
| Experience |
| 1998 |
Short term stay at the Department of Chemistry, Tomás Bata University, Zlín, Czech Republic, in group of Prof. Antonín Klásek (Syntesis of qiuinolin-2,4-dione but-2-enolides). |
| |
| Appointments |
| since 2010 |
Scientist, Nucleoside and nucleotide analogues for biomedical applications, Institute of Organic Chemistry and Biochemistry ASCR, v.v.i., Prague. |
| 2003-2010 |
Member of the Prof. Antonín Holý Research Team, Institute of Organic Chemistry and Biochemistry ASCR, v.v.i., Prague. Research: Syntheses of pyrimidine ANPs as the inhibitors of thymidine phosphorylase and dUTPase. |
| |
| Research interest |
| Organic, applied bioorganic and medicinal chemistry, good knowledge of fluorine chemistry, syntheses of fluorinated compounds with
a potential scale of bioctivities, proposals of the mechanisms and reactivity in fluorine organic reactions, syntheses of pyrimidine acyclic nucleoside
phosphonates as potent antitumor components, programs and methodologies in organic, instrumental analytical and bioorganic chemistry. |
