... / Bioorganická a medicinální chemie / Marcela Krečmerová / Publikace / 2013

2013

Krečmerová M., Jansa P., Dračínský M., Sázelová P., Kašička V., Neyts J., Auwerx J., Kiss E., Goris N., Stepan G., Janeba Z.:

9-[2-(R)-(Phosphonomethoxy)propyl]-2,6-diaminopurine (R)-PMPDAP and its prodrugs: Optimized preparation, including identification of by-products formed, and antiviral evalution in vitro.

Biooorg. Med. Chem. 2013, 21, 1199-1208.

Keough D. T., Špaček P., Hocková D., Tichý T., Vrbková S., Slavětínská L., Janeba Z., Naesens L., Edstein M. D., Chavchich M., Wang T-H., de Jersey J., Guddat L. W.:

Acyclic nucleoside phosphonates containing a second phosphonate group are potent inhibitors of 6‑oxopurine phosphoribosyl transferases and have antimalarial activity.

J. Med. Chem. 2013, 56, 2513-2526.