Research

Research

Research Centers

Gilead Sciences & IOCB Research Centre



Research Groups

Biochemistry and Molecular Biology
Evžen Bouřa (Junior research group)
Jiří Jiráček (Senior research group)
Jan Konvalinka (Senior research group)
Michael Mareš (Senior research group)
Iva Pichová (Senior research group)
Kvido Stříšovský (Junior research group)

Computational Chemistry
Zdeněk Havlas (IOCB Honorary Chair)
Pavel Hobza (IOCB Distinguished Chair)
Pavel Jungwirth (Senior research group)
Lubomír Rulíšek (Senior research group)

Chemistry of Natural Products
Ullrich Jahn (Senior research group)
Irena Valterová (Senior research group)

Bioorganic & Medicinal Chemistry
Michal Hocek (Senior research group)
Zlatko Janeba (Junior research group)
Marcela Krečmerová (Junior research group)
Radim Nencka (Junior research group)
Ivan Rosenberg (Senior research group)

Organic Synthesis
Petr Beier (Senior research group)
Petr Cígler (Junior research group)
Josef Michl (Senior research group)
Ivo Starý (Senior research group)
Jiří Šrogl (Senior research group)

Spectroscopy and Physical Organic Chemistry
Petr Bouř (Senior research group)




Targeted Research Groups

Antimicrobial Peptides (Václav Čeřovský)
Antiobesity Peptides (Lenka Maletínská)
Helquat Chemistry and Biology (Filip Teplý)
Neuroprotectives (Eva Kudová)
Drug Delivery Systems (Tomáš Kraus)
Transport and Diagnostic Nanosystems (Miroslav Ledvina)




Research-Service Groups

Biochemical Pharmacology of Antimetabolites (Helena Mertlíková-Kaiserová)
Bioinformatics (Jiří Vondrášek)
Electromigration Methods (Václav Kašička)
Laboratory of Radioisotopes (Tomáš Elbert)
Mass Spectrometry (Josef Cvačka)
Medicinal Chemistry (Pavel Majer)
NMR Spectroscopy (David Šaman)
Structural Biology (Pavlína Řezáčová)
Virology (Jan Weber)




Selected Service Groups

Analytical Laboratory (Stanislava Matějková)
Development Workshops (Petr Mudra)
Molecular Spectroscopy (Lucie Bednárová)




Research Plan of the Academy of Sciences of the Czech Republic

All the groups of the Institute are supported by the research plan of ASCR No. AV0Z40550506.


AV0Z40550506: Regulation of Life Processes: Chemical Modulators of Selected Biological Systems Relevant to Medicine and Agriculture

The project forms a part of the long–term research mission which is to use the knowledge gained from basic science investigations to discover and/or improve therapeutic and plant protection strategies. Emphasizing integrated interdisciplinary approaches to the study of biomolecular structure and function, the scientific activities evolve around the following four themes: 1) chemistry of biologically important molecules relevant to life–threatening diseases, 2) chemistry of infochemicals relevant to the system plant–insect– microorganism, 3) synthetic approaches to biologically active and bioinspired functional materials, and 4) physico–chemical methods, spectroscopy, and molecular modeling aimed at understanding the mechanism of action of target molecules. The project has two major objectives: 1) to foster interdisciplinary research that integrates chemistry, biochemistry and biology with medical and ecological science, and 2) to train students in interdisciplinary research techniques.