Zaměstnanci

Jméno Brynda Jiří
Pozice Vědecký pracovník
Dr. Jiří Brynda

Jiří Brynda, Ph.D.

Scientist


Structural Biology
Institute of Organic Chemistry and Biochemistry ASCR, v.v.i.
Flemingovo nám. 2, CZ-166 10 Prague 6, Czech Republic

Phone: (+420) 220 183 210 / 220 183 469

 

 
Education
1990-1995 Ph.D. in Biochemistry, Institute of Molecular Genetics, Academy of Sciences of the Czech Republic, Prague.
1981-1986 M.Sc. (Mgr.) in Inorganic Chemistry (specialization: X-ray structural analysis), Department of Inorganic Chemistry, Faculty of Sciences, Charles University, Prague.
 
Experience
1997 (3 months) Postdoctoral fellow at ESRF Grenoble, ID 2 - High Brilliance Beam line (protein crystallography), Grenoble, Switzerland.
1995-1996 Postdoctoral fellow at Laboratory of Structural Immunology, Institute Pasteur, Paris, France.
1994 (3 months) Short-term fellowship at Laboratory of Structural Immunology, Institute Pasteur, Paris, France.
 
Appointments
since 2008 Scientist, Structural biology research-service team, Institute of Organic Chemistry and Biochemistry v.v.i., Academy of Sciences of the Czech Republic, Prague.
1998-2008 Scientist, Department of Gene Manipulations, Institute of Molecular Genetics, Academy of Sciences of the Czech Republic, Prague.
1986-1989 Research assistant (X ray structure analysis of polycrystalic graphite like carbon materials), Institute of Geology, Czechoslovak Academy of Sciences, Prague.
 
Teaching
2003-2008 Determination of 3-D structures of macromolecules course: Department of Biochemistry, Faculty of Natural Sciences, Charles University, Prague.
2002-2008 Determination of 3-D structures of macromolecules course (part of Bioinformatics II lectures): Institute of Physical Biology, University of South Bohemia, České Budějovice.
2001, 2002, 2003, 2005 Teaching at practical courses Crystallization course (CC2001, CC2002 and CC2003, CC2005): University and Academic Center Nové Hrady, Czech Republic.
2004, 2006, 2008 Teaching at FEBS advanced courses: Advanced methods in protein crystallization, University and Academic Center Nové Hrady, Czech Republic.
 
Research interest
Protein crystallography, phase problem, HIV protease, structure-assisted drug design, antibody fragments, metabolism of purines and pirimidines.