Organic chemistry

Tutor	Mgr. Filip Teplý, Ph.D.
Team	Filip Teplý
Topic	Resolution of Helquats on a Large Scale
Faculty	FCHT VŠCHT, PřF UK
Abstract	Helquats represent a very recent addition into the word of small helical aromatics. To address the issues depending on their helical chirality, a robust preparative access to non-racemic series is essential. The goal of this project is to secure a general, cheap, and user-friendly access to multigram quantities of non-racemic helquats. Also applications of non-racemic helquats will be an important part of this project. Leading references: Adriaenssens L., Severa L., Šálová T., Císařová I., Pohl R., Šaman D., Rocha S. V., Finney N. S., Pospíšil L., Slavíček P., Teplý F.: Helquats: A Facile, Modular, Scalable Route to Novel Helical Dications Chemistry - A European Journal 2009, 15, 1072. Jacques J., Collet A., Wilen S. H., Enantiomers, Racemates, and Resolutions, 2nd ed., Krieger, Malabar, Florida, 1994.