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Education |
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2000 – 2006 |
Ph.D. in Organic Chemistry at Department of Organic Chemistry, CharlesUniversity, Prague; under supervision of Dr. Miroslav Ledvina (at Institute of Organic Chemistry and Biochemistry, AS CR). |
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2002-2004 |
Department of teaching and didactics of chemistry, Supplementary pedagogical studies for graduates in chemistry (graduated in 2004). |
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1995 - 2000 |
M.Sc. in Organic Chemistry at Department of Organic Chemistry, Charles University, Prague; under supervision of Dr. Jan Ježek (at Institute of Organic Chemistry and Biochemistry, ASCR). |
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Experience |
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2006 – 2007 |
Postdoctoral fellow in DSBC group, Université Montpellier II, Montpellier, France (with Prof. Auguste Commeyras).(Ligation of dendrimers to solid surfaces). |
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Appointments |
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Since 2008 |
Postdoctoral fellow with RNDr. Miroslav Ledvina, CSc. at the Institute of Organic Chemistry and Biochemistry v.v.i., AS CR. |
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Research interest |
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Sacharide and glycopeptide synthesis, surface-dendrimers chemistry. |
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Selected papers |
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Kovalová A., Ledvina M., Šaman D., Zyka D., Kubíčková M., Žídek L., Sklenář V., Pompach P., Kvan D., Bílý J., Vaněk O., Kubínková Z., Vančurová M., Antolíková M., Lejsková Z., Mrázek H., Rozbeský D., Hofbauerová K., Křen V., Bezouška K.:
Synthetic N-acetylglucosamine based fully branched tetrasaccharide, a mimetic of the endogenous ligand for CD69, activates CD69+ NK cells and killer lymphocytes upon dimerization via a hydrophilic flexible linker.
J. Med. Chem. 53: 4050–4065 (2010).
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