/ Structure / Targeted Research Groups / Antiobesity Peptides / Staff

Staff

Name	Maletínská Lenka
Position	Head of the Targeted Research Group

Lenka Maletínská, Ph.D.

Head of the Team

Antiobesity peptides
Institute of Organic Chemistry and Biochemistry ASCR, v.v.i.
Flemingovo nám. 2, CZ-166 10 Prague 6, Czech Republic

Phone: (+420) 220 183 525
Fax: (+420) 220 183 571


Education
1989-1993	Ph.D. in Biochemistry, at Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic, Prague.
1983-1988	M.Sc. in Biochemistry, at Charles University, Faculty of Natural Sciences, Prague.

Experience
1998-1999	Postdoctoral research associate, Lawrence Berkeley National Laboratory, Berkeley, California, U.S.A., Dr. T. Forte.
1994-1996	Postdoctoral research associate, Dept. Pharmacology, University of Sherbrooke, Canada, Prof. E. Escher.
1991 (4 months)	Fellowship, Centre CNRS-INSERM de Pharmacologie et Endocrinologie, Montpellier, France, Prof. J. Martinez.
1990 (1 month)	Fellowship, Institute of Organic Synthesis, Riga, Latvia, Prof.V.Kluša

Appointments
since 2013	Head of the targeted research team Antiobesity peptides, Institute of Organic Chemistry and Biochemistry v.v.i., Academy of Sciences of the Czech Republic, Prague.
2007-2012	Scientist, Jiracek's group, Institute of Organic Chemistry and Biochemistry v.v.i., Academy of Sciences of the Czech Republic, Prague.
2003-2006	Scientist, Biological Chemistry Department, Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic, Prague.
2001-2003	Maternity Leave.
since 1993	Researcher, Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic, Prague.

Other Experience and Professional Memberships
since 1996	Member of European Peptide Society.
since 2007	Member of American Peptide Society.

Research interest
Structure-activity studies of peptides (cholecystokinin analogues, CART peptides) with special emphasis on their anorectic activity after central and peripheral administration; binding affinities, in vitro and in vivo functional assays. Study of food intake regulation in mouse models of obesity. Ligand binding and signal transduction in cultured cells (study of LDL receptor, putative CART receptor in neuronal cell cultures).