Collaboration

Prof. Josef Štěpánek
Division of Biomolecular Physics, Faculty of mathematic and physics, Charles University, Prague
Raman spectroscopy study on phosphonate oligonucleotides, and their secondary and tertiary structures including, MD study, ab initio calculation, etc.

Dr. Jiří Homola
Institute of Photonics and Electronics, AS CR, Prague
Surface plasmon resonance study on hybridization of phosphonate oligonucleotides and their interactions with enzymes of nucleic acid metabolism.

Prof. Pierre-Yves Turpin
Laboratoire de Biophysique Moléculaire, Cellulaire et Tissulaire UPMC/CNRS, Paris, Evry
Raman spectroscopy of modified nucleotides and oligonucleotides.

Prof. Ivan Havlík
University of Wittwatersrand, SAR
Antimalaric agents based on modified nucleosides and nucleoside phosphonic acids.

Dr. S. M. Gryaznov
Geron Corporation, CA
Biologically active nucleoside phosphonic acids and phosphonate oligonucleotides.

Dr. Dianne Keough and Dr. Luke Guddat
The University of Queensland, Brisbane, Australia
Novel phosphonate aza-nucleotides: Search for selective inhibitors of hypoxanthine-xanthine-guanine-phosphoribosyl transferase from Plasmodium falciparum as potential antimalaric agents.

Dr. Menico Rizzi
DiSCAFF, University of Piemonte Orientale "A. Avogadro", Novara, Italy
Structural analysis of adducts of proteins with oligonucleotides