1976 - 1981

Veterinary University Kosice, DVM degree

1985 - 1989

PhD study: Institute of Animal Physiology and Genetics, Prague, Academy of Sciences of the Czech Republic

1989 - 1992

Reproductive Endocrinology, Research Institute of Animal Production, Prague, Czech Republic

1993-present

Senior Scientist - Institute of Animal Physiology and Genetics, Academy of Sciences of the Czech Republic, Libechov

 1997

Society for the Study of Reproduction

 2000

European Society of Human Reproduction and Embryology

1992

Norwegian College of Veterinary Medicine, Oslo, Norway (3 months)

1994

INSERM, Clamart, France (3 months) collaboration with J. Testart, Lefevre B...

1997

OECD Fellowship Award (26 weeks) -Cancer Research Center, Ottawa, Canada- collaboration with BC Vanderhyden, at present director of Society of Study of Reproduction in US

2002

OECD Fellowship Award (26 weeks) Department of Public Health and Cell Biology, Faculty of Medicine, University of Rome, Italy, collaboration with Salustri A, Camaioni A,

2002 - 2007

Program of Scientific and Technological Co-operation between the Government of the Italian  Republic and the government of the Czech Republic; Department of Public Health and Cell Biology, Faculty of Medicine, University of Rome, Italy - Visiting Research- Scientist (6 x 3 months)

OECD Fellowship Award (13 weeks) - ) Department of Public Health and Cell Biology, Faculty of Medicine, University of Rome, Italy, collaboration with Salustri A, Camaioni A,

1994-1996

GA AV–(A745 401)

2001-2003

GA AV–(A5045102/01)

2005-2007

GA CR–(305/05/0960)

GA CR - (524/98/0231)

GA CR- (504 5102/01)

Grant 2003 from Ministro Italiano dell’Istruzione, dell’Universita et della Ricerca Scientifica

Grant 52/ZV2 from Ministry of School, Youth and Education, Program of Scientific and Technological Co-operation between the Government of the Italian Republic and the government of the Czech Republic Program

National Research Initiative Competitive Grants N. 2007-35203-18274 and N. 2011-67015-20025 from the USDA National Institute of Food and Agriculture

Grant PRIN 2005 from the Italy Ministry of Education

GA CR (523/08/0111)

GA CR (P502/11/0593)

GA CR (524/01/0903)

Institutional Research Project AV0Z50450515

Grant-in-Aid (Bio Media Program) from Ministry of Agriculture, Forestry

Priority Research Collaboration between Slovak Academy of Sciences and Academy of Sciences of the Czech Republic (2012-2014): (N. 18. Coordination between oocyte and granulosa cells: paracrine and autocrine regulation of ovarian intrafollicular processes.)

Cancer research activity:

Project supported by GlaxoSmithKline, s.r.o. Czech Republic (2011) and by grant P502/11/0593 from Grant Agency of the Czech Republic. 

 2013

Lapatinib inhibits meiotic maturation of oocyte-cumulus complexes cultured in vitro in gonadotropins-supplemented medium. Nagyova E, Nemcova L, Mlynarcikova A, Scsukova S, Kalous J.Fertil Steril. 2013 Jan 29. doi:pii: S0015-0282(13)00002-2. 10.1016/j.fertnstert.2012.12.040. [Epub ahead of print]

 2012

Regulation of cumulus expansion and hyaluronan synthesis in porcine oocyte-cumulus complexes during in vitro maturation. Nagyova Eva. ENDOCRINE REGULATIONS, 46; 225-235,2012.

Inhibition of proteasomal proteolysis affects expression of extracellular matrix components and steroidogenesis in porcine oocyte-cumulus complexes Nagyova E.; Scsukova S.; Nemcova L.; et al. DOMESTIC ANIMAL ENDOCRINOLOGY 42;: 1; 50-62 ,.2012

 2011

Activation of Cumulus Cell SMAD2/3 and Epidermal Growth Factor Receptor Pathways Are Involved in Porcine Oocyte-Cumulus Cell Expansion and Steroidogenesis Nagyova Eva; Camaioni Antonella; Scsukova Sona; et al. MOLECULAR REPRODUCTION AND DEVELOPMENT ; 78: 6;: 391-402, 2011

Effect of epidermal growth factor-like peptides on pig cumulus cell expansion, oocyte maturation, and acquisition of developmental competence in vitro: comparison with gonadotropins.Prochazka Radek; Petlach Michal; Nagyova Eva; et al. REPRODUCTION 141 : 4: 425-435, 2011

 2009

Development of Functional LH Receptors on Pig Cumulus-Oocyte Complexes Cultured In Vitro by a Novel Two-Step Culture System. Prochazka Radek; Nemcova Lucie; Nagyova Eva; et al. MOLECULAR REPRODUCTION AND DEVELOPMENT ; 76: 8 : 751-761, 2009

Expression of Tumor Necrosis Factor Alpha-Induced Protein 6 Messenger RNA in Porcine Preovulatory Ovarian Follicles Nagyova Eva; Nemcova Lucie; Prochazka Radek JOURNAL OF REPRODUCTION AND DEVELOPMENT 55 ; 3: 231-235 , 2009

Effects of selected endocrine disruptors on meiotic maturation, cumulus expansion, synthesis of hyaluronan and progesterone by porcine oocyte-cumulus complexes. Mlynarcikova Alzbeta; Nagyova Eva; Fickova Maria; et al. TOXICOLOGY IN VITRO : 23 : 3 ; 371-377, 2009

 2008

Synthesis of tumor necrosis factor alpha-induced protein 6 in porcine preovulatory follicles: A study with A38 antibody Nagyova Eva; Camaioni Antonella; Prochazka Radek; et al. BIOLOGY OF REPRODUCTION 78: 5 ; 903-909, 2008

Proteolytic activity of the 26s proteasome is required for the meiotic resumption, germinal vesicle breakdown, and cumulus expansion of porcine cumulus-oocyte complexes matured in vitro. Yi Young-Joo; Nagyova Eva; Manandhar Gaurishankar; et al. BIOLOGY OF REPRODUCTION : 78: 1 : 115-126, 2008

 2007

Molecular mechanisms of insulin-like growth factor 1 promoted synthesis and retention of hyaluronic acid in porcine oocyte-cumulus complexes. Nemcova Lucie; Nagyova Eva; Petlach Michal; et al. BIOLOGY OF REPRODUCTION 76 : 6: 1016-1024, 2007

 2004

Covalent transfer of heavy chains of inter-alpha-trypsin inhibitor family proteins to hyaluronan in in vivo and in vitro expanded porcine oocyte-cumulus complexes. Nagyová E, Camaioni A, Procházka R, Salustri A. (2004). Biology of Reproduction 71: 1838-1843

Expression of growth differentiation factor 9 messenger RNA in porcine growing and preovulatory ovarian follicles. Procházka R, Němcová L, Nagyová E, Kaňka J. (2004) Biology of Reproduction 71: 1290-1295

Inhibitory effect of cadmium and tobacco alkaloids on expansion of porcine oocyte-cumulus complexes. Mlynarcikova A, Scsukova S, Vrsanska S, Nagyova E, Fickova M, Kolena J (2004) Cent Eur J Public Health. Suppl: S 62-4.

 2003

Evaluation of members of the TGFβ superfamily as candidates for the oocyte factors that control mouse cumulus expansion and steroidogenesis. Vanderhyden BC, Macdonald EA, Nagyova E and Dhawan A (2003) Reproduction Supplement 61: 55-70

Components of cigarette smoke inhibit expansion of oocyte –cumulus complexes from porcine follicles. Vrsanska S, Nagyova E, Mlynarcikova A (2003) Phys Research 52; 383-387

Epidermal growth factor-receptor tyrosine kinase activity regulates expansion of porcine oocyte-cumulus cell-complexes in vitro. Procházka R, Kaláb P, Nagyová E (2003) Biology of Reproduction 68:797-803.

 2001

Gossypol inhibits follicle-stimulating hormone and epidermal growth factor –stimulated expansion of oocyte-cumulus complexes from porcine preovulatory follicles. Kolena J, Vrsanka S, Nagyova E (2001) Phys Research 50:627-630

Effect of intraovarian factors on porcine follicular cells: cumulus expansion, granulosa and cumulus cells progesterone production. Ježová M., Scsuková S., Nagyová E., Vranová J., Procházka R., Kolena J (2001). Animal Reproduction Science 65:115-126

 2000

Secretion of paracrine factors enabling expansion of cumulus cells is developmentally regulated in pig oocytes. Nagyová E, Vanderhyden B.C. and Procházka R (2000) Biology of Reproduction 63:1149-1156

Developmental regulation of effect of epidermal growth factor on porcine oocyte-cumulus cell complexes: Nuclear maturation, expansion, and F-actin remodeling. Prochazka R, Srsen V, Nagyova E (2000) Mol Reprod Dev 56:63-73

 1999

Ooocytectomy does not influence synthesis of hyaluronic acid by pig cumulus cells: Retention of hyaluronic acid after insulin-like growth factor-I treatment in serum-free medium. Nagyova E, Prochazka R, Vanderhyden BC (1999) Biol Reprod 61: 569-574

 1998

Effects of follicle-stimulating hormone, bovine somatotropin and okadaic acid on cumulus expansion and nuclear maturation of Blue fox (Alopex lagopus) oocytes in vitro. Srsen V, Kalous J, Nagyova E, Sutovsky P, King WA, Motlik J (1998) Zygote: 6: 299-309

Paracrine and autocrine regulation of cumulus expansion in porcine follicles. Motlik J, Prochazka R, Nagyova E (1998) Reprod in Dom Anim 33: 181-185

Secretion of cumulus expansion –enabling factor (CEEF) in porcine follicles. . Prochazka R, Nagyova E, Brem G, Schellander K, Motlik J (1998) Mol Reprod Dev 49: 141-149

 1993

Is cAMP decrease essential for resumption of meiosis in mouse oocytes? Nagyova E, Kalous J, Sutovsky P, Motlik J. (1993) Reprod Nutr Dev 33: 419-28.

Lack of effect of oocytectomy on expansion of the porcine cumulus. Prochazka R, Nagyova E, Rimkevicova Z, Nagai T, Kikuchi K, Motlik J. (1991) J Reprod Fertil 93:569-76.