Academy of Sciences of the Czech Republic

Rumburska 89   ­  277 21 Libechov

Czech Republic

Office: +420 315 639 591 ­   Fax: +420 315 639 510

 EDUCATION & PROFESSIONAL CAREER:

• Present position – Young investigator, Institute of Animal Physiology and Genetics Academy of Sciences, Czech Republic
   
• Postdoctoral scholar – 2009 - 2012 - University of California San Francisco, USA, RNA binding proteins and regulation of meiotic cell cycle
   
• Ph.D. in Developmental biology – 2004 - 2008 - Charles University in Prague, Czech Republic,   Protein Synthesis and degradation in mammalian oocytes
   
• MSc in Animal Sciences – 1996 - 2001 - Slovak Agricultural University, Slovakia

RESEARCH INTERESTS:

• Germ cell transcriptome and translational program
• RNA processing in the germ cells and early stage embryos
• Protein degradation pathway in the meiosis and fertilization

PAPERS:

• Toralova T, Benesova V, Kepkova K, Vodicka P, Susor A, Kanka J. Bovine preimplantation embryos with silenced nucleophosmin mRNA are able to develop until the blastocyst stage. Reproduction. 2012.

• Mtango NR,  Sutovsky M, Susor A, Zhong Z, Latham KE, Sutovsky P. Essential role of maternal UCHL1 and UCHL3 in fertilization and preimplantation embryo development. J Cell Physiol . 2012, 227:1592-1603.

• Oh JS, Susor A, Conti M. Protein Tyrosine Kinase Wee1B is Essential for Metaphase II Exit in Mouse Oocytes. Science. 2011, 332:462-465.

• Karabinova P, Kubelka M, Susor A. Proteasomal degradation of ubiquitinated proteins in oocyte meiosis and fertilization in mammals. Cell Tissue Res. 2011, 346:1-9.

• Liskova L, Susor A, Pivonkova K, Saskova A, Karabinova P, Kubelka M. Detection of condensin I and II in maturing pig oocytes. Reprod Fertil Dev. 2010, 22:644-652.

• Susor A, Liskova L, Toralova T, Pavlok A, Pivonkova K, Karabinova P, Lopatarova M, Sutovsky P, Kubelka M. Role of ubiquitin C-terminal hydrolase-L1 in antipolyspermy defense of mammalian oocytes. Biol Reprod. 2010, 82:1151-1161.

• Toralova T, Susor A, Nemcova L, Kepkova K, Kanka J. Silencing CENPF in bovine preimplantation embryo induces arrest at 8-cell stage. Reproduction. 2009, 138:783-791.

• Kalous J, Kubelka M, Solc P, Susor A, Motlik J. AKT (protein kinase B) is implicated in meiotic maturation of porcine oocytes. Reproduction. 2009, 138:645-654.

• Susor A, Jelinkova L, Karabinova P, Torner H, Tomek W, Kovarova H, Kubelka M. Regulation of cap-dependent translation initiation in the early stage porcine parthenotes. Mol Reprod Dev. 2008, 75:1716-1725.

• Pelech S, Jelinkova L, Susor A, Zhang H, Shi X, Pavlok A, Kubelka M & Kovarova H. Antibody Microarray Analyses of Signal Transduction Protein Expression and Phosphorylation During Porcine Oocyte Maturation. J Prot Res. 2008, 7:2860-2871.

• Ellederova Z, Cais O, Susor A, Uhlirova K, Kovarova H, Jelinkova L, Tomek W, Kubelka M. ERK1/2 map kinase metabolic pathway is responsible for phosphorylation of translation initiation factor eIF4E during in vitro maturation of pig oocytes. Mol Reprod Dev. 2008, 75:309-317.

• Susor A, Ellederova Z, Jelinkova L, Halada P, Kavan D, Kubelka M, Kovarova H. Proteomic Analysis of porcine oocytes during in vitro maturation reveals essential role for the ubiquitin C- terminal hydrolase-L1. Reproduction. 2007, 134:559-568.

Accomplishment of meiosis I in the oocyte