People

Name Grantz-Šašková Klára
Position Scientist
Grantz Šašková

Klára Grantz Šašková, Ph.D.

Scientist


Proteases of Human Pathogens
Institute of Organic Chemistry and Biochemistry ASCR, v.v.i.
Flemingovo nam. 2, CZ-166 10 Prague 6, Czech Republic

Phone: (+420) 220 183 518
Fax: (+420) 220 183 578

 

 
Education
since 2010 Postdoctoral fellow in Jan Konvalinka's laboratory and since 2013 also the member of Jan Konvalinka BIOCEV group, Institute of Organic Chemistry and Biochemistry AS CR, Prague.
2006-2010 Ph.D. in biochemistry, Faculty of Science, Charles University, Prague, Czech Republic.
Ph.D. thesis "HIV-1 Protease: Insights into Drug Resistance Development" under supervision of Dr. Jan Konvalinka at the Institute of Organic Chemistry and Biochemistry AS CR, Prague.
2001-2006 M.Sc. in biochemistry, Faculty of Science, Charles University, Prague, Czech Republic.
Diploma thesis "The Influence of Individual Mutations in HIV Protease on Reduced Susceptibility to the Protease Inhibitor Lopinavir" under supervision of Dr. J.Konvalinka at the Institute of Organic Chemistry and Biochemistry ASCR, Prague.
 
Courses
2006 Scholarship from FEBS for Biocrys 2006 "Fundamentals of Modern Methods in Biocrystallography".
2006 Scholarship for 3rd TID workshop of BIOXHIT TID Centre in Poznan.
2005 Scholarship for "6th Annual Symposium on Antiviral Drug Resistance: Targets and Mechanisms".
 
Research interest
  • HIV drug development focusing on HIV protease and viral assembl
  • shuttling proteins in ubiquitin-proteasom system
  • specific drug targeting