Curriculum vitae:
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1976 - 1981
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Veterinary University Kosice, DVM degree
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1985 - 1989
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PhD study: Institute of Animal Physiology and Genetics, Prague, Academy of Sciences of the Czech Republic
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1989 - 1992
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Reproductive Endocrinology, Research Institute of Animal Production, Prague, Czech Republic
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1993-present
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Senior Scientist - Institute of Animal Physiology and Genetics, Academy of Sciences of the Czech Republic, Libechov
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Specialization:
Interplay between granulosa cells and oocyte: Meiotic maturation of mammalian oocytes, organization
of cumulus oophorus extracellular matrix, steroidogenesis and proteasomal proteolysis .
Societies:
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1997
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Society for the Study of Reproduction
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2000
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European Society of Human Reproduction and Embryology
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Internship abroad:
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1992
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Norwegian College of Veterinary Medicine, Oslo, Norway (3 months)
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1994
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INSERM, Clamart, France (3 months) collaboration with J. Testart, Lefevre B...
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1997
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OECD Fellowship Award (26 weeks) -Cancer Research Center, Ottawa, Canada- collaboration with BC Vanderhyden, at present director of Society of Study of Reproduction in US
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2002
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OECD Fellowship Award (26 weeks) Department of Public Health and Cell Biology, Faculty of Medicine, University of Rome, Italy, collaboration with Salustri A, Camaioni A,
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2002 - 2007
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Program of Scientific and Technological Co-operation between the Government of the Italian Republic and the government of the Czech Republic; Department of Public Health and Cell Biology, Faculty of Medicine, University of Rome, Italy - Visiting Research- Scientist (6 x 3 months)
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| 2013 |
OECD Fellowship Award (13 weeks) - ) Department of Public Health and Cell Biology, Faculty of Medicine, University of Rome, Italy, collaboration with Salustri A, Camaioni A,
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Projects (principal scientist):
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1994-1996
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GA AV–(A745 401)
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2001-2003
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GA AV–(A5045102/01)
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2005-2007
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GA CR–(305/05/0960)
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Projects collaboration:
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GA CR - (524/98/0231)
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GA CR- (504 5102/01)
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Grant 2003 from Ministro Italiano dell’Istruzione, dell’Universita et della Ricerca Scientifica
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Grant 52/ZV2 from Ministry of School, Youth and Education, Program of Scientific and Technological Co-operation between the Government of the Italian Republic and the government of the Czech Republic Program
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National Research Initiative Competitive Grants N. 2007-35203-18274 and N. 2011-67015-20025 from the USDA National Institute of Food and Agriculture
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Grant PRIN 2005 from the Italy Ministry of Education
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GA CR (523/08/0111)
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GA CR (P502/11/0593)
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GA CR (524/01/0903)
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Institutional Research Project AV0Z50450515
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Grant-in-Aid (Bio Media Program) from Ministry of Agriculture, Forestry
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Priority Research Collaboration between Slovak Academy of Sciences and Academy of Sciences of the Czech Republic (2012-2014): (N. 18. Coordination between oocyte and granulosa cells: paracrine and autocrine regulation of ovarian intrafollicular processes.)
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Cancer research activity:
Project supported by GlaxoSmithKline, s.r.o. Czech Republic (2011) and by grant P502/11/0593 from Grant Agency of the Czech Republic.
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Publications:
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Lapatinib inhibits meiotic maturation of oocyte-cumulus complexes cultured in vitro in gonadotropins-supplemented medium. Nagyova E, Nemcova L, Mlynarcikova A, Scsukova S, Kalous J.Fertil Steril. 2013 Jan 29. doi:pii: S0015-0282(13)00002-2. 10.1016/j.fertnstert.2012.12.040. [Epub ahead of print]
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2011
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Nagyova Eva, Camaioni Antonella, Scsukova Sona, Mlymarcikova Alzbeta, Prochazka Radek, Nemcova Lucie, Salustri Antonietta.Activation of cumulus cell SMAD2/3 and epidermal growth factor receptor pathways are involved in porcine oocyte-cumulus cell expansion and steroidogenesis Molecular Reproduction and Development (2011) 78: 391-402
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Nagyova Eva, Scsukova Sona, Nemcova Lucie, Mlynarcikova Alzbeta, Yi Joung Joo, Sutovsky Miriam, Sutovsky Peter Inhibition of proteasomal proteolysis affects expression of extracellular matrix components and steroidogenesis in porcine oocyte-cumulus complexesDomestic Animal Endocrinology (2011) 10.1016/j.domaniend.2011.09.003
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2009
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Nagyová, Eva - Němcová, Lucie - Procházka, Radek
Expression of tumor necrosis factor alpha-induced protein 6 messenger RNA in porcine preovulatory ovarian follicles.
Journal of Reproduction and Development (2009) 55: 231-235
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Mlynarčíková, A. - Nagyová, Eva - Ficková, M. - Scsuková, S.
Effects of selected endocrine disruptors on meiotic maturation, cumulus expansion, synthesis of hyaluronan and progesterone by porcine oocyte-cumulus complexes.
Toxicology in Vitro (2009) 23: 371-377
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2008
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Nagyová, Eva - Camaioni, A. - Procházka, Radek - Day, A. J. - Salustri, A.
Synthesis of tumor necrosis factor alpha induced protein 6 in porcine preovulatory follicles; A study with A38 antibody.
Biology of Reproduction (2008) 78: 903-909
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2008
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Yi, Young Joo - Nagyová, Eva - Manandhar, G. - Procházka, Radek - Šutovsky, M. - Park, C. S. - Šutovský, P.
Proteolytic activity of the 26S proteasome is required for the meiotic resumption, germinal vesicle breakdown and cumulus expansion of porcine cumulus-oocyte complexes matured in vitro.
Biology of Reproduction (2008) 78:115-126
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2004
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Nagyová, Eva - Camaioni, A. - Procházka, Radek - Salustri, A.
Covalent transfer of heavy chains of inter-alpha-trypsin inhibitor family proteins to hyaluronan in in vivo and in vitro expanded porcine oocyte-cumulus complexes.
Biology of Reproduction (2004) 71:1838-1843
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2003
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Vanderhyden, B. C. - Macdonald, E. A. - Nagyová, Eva - Dhawan, A.
Evaluation of members of the TGF beta superfamily as candidates for the oocyte factors that control mouse cumulus expansion and steroidogenesis.
Reproduction (2003) 61: 55-70
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2003
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Vršanská Sylvia, Nagyova Eva, Mlynarcikova Alzbeta, Fickova Maria, Kolena Jaroslav
Components of cigarette smoke inhibit expansion of oocyte-cumulus comlexes from porcine follicles.
Physiological Research (2003) 52: 383-387
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2000
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Nagyová Eva, Vanderhyden B.C. and Procházka R Secretion of paracrine factors enabling expansion of cumulus cells is developmentally regulated in pig oocytes. Biology of Reproduction (2000) 63:1149-1156
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1999
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Nagyova Eva, Prochazka R, Vanderhyden BC (1999)Ooocytectomy does not influence synthesis of hyaluronic acid by pig cumulus cells: Retention of hyaluronic acid after insulin-like growth factor-I treatment in serum-free medium. Biology of Reproduction (1999) 61: 569-574
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