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Projects
Records found: 53
GAP302/10/1022
Chromatin dynamics during DNA repair
Contractor: Institute of Biophysics of the ASCR, v. v. i.
Principal investigator: Kozubek Stanislav
Research years: 2010-2014
GAP301/10/0598
Metallodrugs based on osmium, platinum and ruthenium complexes. From mechanistic studies to novel, more efficient chemotherapy of cancer
Contractor: Institute of Biophysics of the ASCR, v. v. i.
Principal investigator: Brabec Viktor
Research years: 2010-2014
GAP205/10/2378
Induced organization of biomolecules at interfaces by interacting with electrically charged surfaces as a tool for medical diagnostics
Contractor: Institute of Biophysics of the ASCR, v. v. i.
Principal investigator: Hasoň Stanislav
Research years: 2010-2014
GAP305/10/0930
Sex chromosomes and dynamics of transposable elements
Contractor: Institute of Biophysics of the ASCR, v. v. i.
Principal investigator: Kejnovský Eduard
Research years: 2010-2014
GAP501/10/0102
Comparative Analysis of Plant Sex Chromosomes
Contractor: Institute of Biophysics of the ASCR, v. v. i.
Principal investigator: Vyskot Boris
Research years: 2010-2014
GAP206/11/1638
Novel electrochemical sensors and sensing techniques for the analysis of nucleic acids structure and interactions
Contractor: Institute of Biophysics of the ASCR, v. v. i.; J. Heyrovsky Institute of Physical Chemistry of the ASCR, v. v. i.
Principal investigator: Fojta Miroslav; Yosypchuk Bogdan
Research years: 2011-2015
GAP301/11/2055
New methods of analysis of proteins and their glycosylation in cancer - combination of electrochemistry, microfludic biosensors and mass spectrometry
Contractor: Institute of Biophysics of the ASCR, v. v. i.; Institute of Analytical Chemistry of the ASCR, v. v. i.
Principal investigator: Foret František; Paleček Emil
Research years: 2011-2014
GAP208/11/1822
Structure and dynamics of DNA. Advanced computational studies
Contractor: Institute of Biophysics of the ASCR, v. v. i.
Principal investigator: Šponer Jiří
Research years: 2011-2015
GAP205/11/0856
Thermodynamics of DNA damaged by physical and chemical agents
Contractor: Institute of Biophysics of the ASCR, v. v. i.
Principal investigator: Malina Jaroslav
Research years: 2011-2015
GAP303/11/0128
Role of adenosine A3 receptor signaling in regulation of hematopoiesis: knowledge obtained from adenosine A3 receptor knock-out mice
Contractor: Institute of Biophysics of the ASCR, v. v. i.
Principal investigator: Hofer Michal
Research years: 2011-2014
GBP305/12/G034
Centre for RNA Biology
Contractor: Institute of Microbiology of the ASCR, v. v. i.; Institute of Biophysics of the ASCR, v. v. i.; Institute of Molecular Genetics of the ASCR, v. v. i.
Principal investigator: Valášek Leoš; Šponer Jiří; Staněk David
Research years: 2012-2018
GBP206/12/G151
Center of novel approaches to bioanalysis and molecular diagnostics
Contractor: Institute of Biophysics of the ASCR, v. v. i.; Institute of Organic Chemistry and Biochemistry of the ASCR, v. v. i.
Principal investigator: Fojta Miroslav; Hocek Michal
Research years: 2012-2018
GBP302/12/G157
Dynamics and Organization of Chromosomes in the Cell Cycle and during Differentiation under Normal and Pathological Conditions
Contractor: Institute of Biophysics of the ASCR, v. v. i.
Principal investigator: Kozubek Stanislav
Research years: 2012-2018
GBP501/12/G090
Evolution and Function of Complex Plant Genomes
Contractor: Institute of Biophysics of the ASCR, v. v. i.; Biology Centre of the ASCR, v. v. i.; Institute of Experimental Botany of the ASCR, v. v. i.
Principal investigator: Vyskot Boris; Macas Jiří; Doležel Jaroslav
Research years: 2012-2018
GAP501/12/2220
Sex chromosome evolution - chromosome-specific genomics in genus Silene
Contractor: Institute of Biophysics of the ASCR, v. v. i.; Institute of Experimental Botany of the ASCR, v. v. i.
Principal investigator: Hobza Pavel; Šafář Jan
Research years: 2012-2016
GAP208/12/1878
Catalytic strategies of RNA and RNP enzymes studied by multi-scale computational approach
Contractor: Institute of Biophysics of the ASCR, v. v. i.
Principal investigator: Šponer Jiří
Research years: 2012-2016
GAP205/12/0466
DNA quadruplexes in the human genome associated with diseases and aging
Contractor: Institute of Biophysics of the ASCR, v. v. i.
Principal investigator: Vorlíčková Michaela
Research years: 2012-2017
GAP305/12/2475
HMGB proteins: involvement in biology of telomeres and human embryonic stem cells
Contractor: Institute of Biophysics of the ASCR, v. v. i.
Principal investigator: Štros Michal
Research years: 2012-2015
GPP301/12/P407
The role of MDM2 in epithelial-to-mesenchymal transition: implication for cancer progression
Contractor: Institute of Biophysics of the ASCR, v. v. i.
Principal investigator: Slabáková Eva
Research years: 2012-2015
GAP206/12/2378
Influence of conformation and chemical modification on the behavior of oligonucleotides at electrodes: towards the development of DNA sensors
Contractor: Institute of Biophysics of the ASCR, v. v. i.
Principal investigator: Havran Luděk
Research years: 2012-2014
GCP305/12/J038
Importance of the interaction of myeloperoxidase with the endothelial glycocalyx for leukocyte recruitment and vascular fuction
Contractor: Institute of Biophysics of the ASCR, v. v. i.
Principal investigator: Kubala Lukáš
Research years: 2012-2014
GP13-10948P
Alternative telomeres with uknown sequence in plants
Contractor: Institute of Biophysics of the ASCR, v. v. i.
Principal investigator: Peška Vratislav
Research years: 2013-2015
GP13-11563P
Analysis of replication and DNA damage response in plants deficient in accurate chromatin assembly
Contractor: Institute of Biophysics of the ASCR, v. v. i.
Principal investigator: Dvořáčková Martina
Research years: 2013-2015
GA13-08273S
Biophysical analysis of DNA condensation. Effect of new organometallic compounds of biological significance
Contractor: Institute of Biophysics of the ASCR, v. v. i.
Principal investigator: Nováková Olga
Research years: 2013-2016
GA13-06264S
Sex determination and sexual dimorphism in plants
Contractor: Institute of Biophysics of the ASCR, v. v. i.
Principal investigator: Janoušek Bohuslav
Research years: 2013-2016
GA13-28310S
Evolučně konzervované strukturní vlastnosti centromerické a telomerické DNA
Contractor: Institute of Biophysics of the ASCR, v. v. i.
Principal investigator: Vorlíčková Michaela
Research years: 2013-2016
GA13-36108S
Interactions of p53 family proteins with biologically significant DNA quadruplexes
Contractor: Institute of Biophysics of the ASCR, v. v. i.
Principal investigator: Brázdová Marie
Research years: 2013-2015
GA13-09766S
Lipid nutritional factors as modulators of xenobiotic metabolism and toxicity in colon epithelial cells
Contractor: Institute of Biophysics of the ASCR, v. v. i.
Principal investigator: Kozubík Alois
Research years: 2013-2017
GA13-29358S
Materiály pro integraci živočišných buněk a organické elektroniky pro budoucí bioelektronické zařízení
Contractor: Institute of Biophysics of the ASCR, v. v. i.
Principal investigator: Víteček Jan
Research years: 2013-2016
GP13-40824P
New Role for Nitrated Fatty Acid in Modulation of Phagocyte-derived Inflammatory Responses
Contractor: Institute of Biophysics of the ASCR, v. v. i.
Principal investigator: Ambrožová Gabriela
Research years: 2013-2015
GP13-34962P
Silene dioica as a model species for heavy metal tolerance
Contractor: Institute of Biophysics of the ASCR, v. v. i.
Principal investigator: Čegan Radim
Research years: 2013-2015
GA13-10057S
Structure, expression and evolution of ribosomal RNA genes in plant genomes: new approaches to old questions
Contractor: Institute of Biophysics of the ASCR, v. v. i.
Principal investigator: Kovařík Aleš
Research years: 2013-2016
GA13-06943S
Structural and functional components of plant telomeres
Contractor: Institute of Biophysics of the ASCR, v. v. i.; Institute of Experimental Botany of the ASCR, v. v. i.
Principal investigator: Sýkorová Eva; Honys David
Research years: 2013-2017
GA13-07822S
The role of epigenetic processes in DNA repair
Contractor: Institute of Biophysics of the ASCR, v. v. i.
Principal investigator: Bártová Eva
Research years: 2013-2016
GP13-40882P
Role of L-arginine, methylarginines and their metabolism in regulation of endothelial homeostasis
Contractor: Institute of Biophysics of the ASCR, v. v. i.
Principal investigator: Pekarová Michaela
Research years: 2013-2014
GA13-00956S
Úloha proteinů rodiny Anterior gradient při vzniku a vývoji nádorových onemocnění
Contractor: Institute of Biophysics of the ASCR, v. v. i.
Principal investigator: Ostatná Veronika
Research years: 2013-2017
GA13-07711S
The role of Hippo signaling pathway and organic toxicants in alterations of liver cell function and xenobiotic metabolism
Contractor: Institute of Biophysics of the ASCR, v. v. i.
Principal investigator: Vondráček Jan
Research years: 2013-2016
GP13-31488P
Influence of Dishevelled posttranslational modifications on Wnt signaling pathways
Contractor: Institute of Biophysics of the ASCR, v. v. i.
Principal investigator: Bernatík Ondřej
Research years: 2013-2015
GA14-21053S
Mechanistic studies on dual targeting of DNA and histone deacetylase with bifunctional inhibitors
Contractor: Institute of Biophysics of the ASCR, v. v. i.
Principal investigator: Brabec Viktor
Research years: 2014-2016
GP14-33947P
Regulation of the embryonic stem cell pluripotency factor Oct4 via guanine quadruplex in its promoter
Contractor: Institute of Biophysics of the ASCR, v. v. i.
Principal investigator: Renčiuk Daniel
Research years: 2014-2016
GA14-34632S
Genome wide range mapping of rDNA structure and epigenetic modfications in plant hybrids using third generation single molecule real-time sequencing
Contractor: Institute of Biophysics of the ASCR, v. v. i.
Principal investigator: Matyášek Roman
Research years: 2014-2016
GA14-12010S
Theoretical and experimental studies on the origin of life
Contractor: Institute of Biophysics of the ASCR, v. v. i.; J. Heyrovsky Institute of Physical Chemistry of the ASCR, v. v. i.
Principal investigator: Šponer Judit E.; Ferus Martin
Research years: 2014-2016
EE2.3.30.0030
Development of human resources in the field of cell biology
Contractor: Institute of Biophysics of the ASCR, v. v. i.
Principal investigator: Kozubek Stanislav
Research years: 2012-2015
EE2.3.30.0019
Development of modern trends in experimental biology: importance of biomolecular interactions for functions of cellular structures
Contractor: Institute of Biophysics of the ASCR, v. v. i.
Principal investigator: Kozubek Stanislav
Research years: 2012-2015
LD12039
The influence of higher-order chromatin structure on the mechanism of DNA double-strand break (DSB) repair and formation of chromosomal translocations in cells irradiated with gamma rays and medically relevant ion beams
Contractor: Institute of Biophysics of the ASCR, v. v. i.
Principal investigator: Falk Martin
Research years: 2012-2014
LH13096
Targeting DNA interactions with platinum anticancer drugs with damaged-DNA binding-proteins
Contractor: Institute of Biophysics of the ASCR, v. v. i.
Principal investigator: Brabec Viktor
Research years: 2013-2015
LH14002
Functional Genomics of Dioecious Plants
Contractor: Institute of Biophysics of the ASCR, v. v. i.
Principal investigator: Vyskot Boris
Research years: 2014-2016
LH14317
Mechanisms of antitumor effects of non-traditional platinum
Contractor: Institute of Biophysics of the ASCR, v. v. i.
Principal investigator: Brabec Viktor
Research years: 2014-2016
LD14019
Molecular and cellular pharmacology of new conjugated organometalic compound. Relations to development of anticancer drugs
Contractor: Institute of Biophysics of the ASCR, v. v. i.
Principal investigator: Kašpárková Jana
Research years: 2014-2016
LD14030
Molecular mechanisms of serotoninergic system interactions with cells of immune system
Contractor: Institute of Biophysics of the ASCR, v. v. i.
Principal investigator: Číž Milan
Research years: 2014-2016
