Institute of Molecular Genetics of the ASCR, v. v. i.

GA ČR

GA14-34264S
Role of R2TP complex in DNA damage response and cell proliferation
Contractor: Institute of Molecular Genetics of the ASCR, v. v. i.
Principal investigator: Hořejší Zuzana
Research years: 2014-2016

GP14-20839P
The role of Pituitary homeobox gene in anterior specification and left-right asymmetry in the basal chordate amphioxus
Contractor: Institute of Molecular Genetics of the ASCR, v. v. i.
Principal investigator: Soukup Vladimír
Research years: 2014-2016

GA14-09807S
Signaling pathways involved in mast cell chemotaxis
Contractor: Institute of Molecular Genetics of the ASCR, v. v. i.
Principal investigator: Dráberová Eduarda
Research years: 2014-2016

GA14-30186S
Hidden relevant functional pathways in host response to Leishmania infection revealed in focused genomic constructions
Contractor: Institute of Molecular Genetics of the ASCR, v. v. i.
Principal investigator: Lipoldová Marie
Research years: 2014-2016

GP14-17194P
Synthetic oligofuranosides, their enzymatic preparation and the mode of cellular signalling
Contractor: Institute of Molecular Genetics of the ASCR, v. v. i.
Principal investigator: Chlubnová Ilona
Research years: 2014-2016

GA14-10100S
Utilization of novel mouse strains for investigation of the NK cell regulatory role in development and therapy of cancer
Contractor: Institute of Molecular Genetics of the ASCR, v. v. i.
Principal investigator: Indrová Marie
Research years: 2014-2016

GA MPO

FR-TI3/067
Geneticky modifikované polymerázy a jejich využití pro amplifikaci nepurifikované DNA
Contractor: Institute of Molecular Genetics of the ASCR, v. v. i.
Principal investigator: Dráber Petr
Research years: 2011-2014

FR-TI3/588
Vývoj kitu pro detekci mutací strukturních proteinů buňky
Contractor: Institute of Molecular Genetics of the ASCR, v. v. i.
Principal investigator: Hozák Pavel
Research years: 2011-2015

FR-TI4/660
Multimodální holografický mikroskop
Contractor: Institute of Molecular Genetics of the ASCR, v. v. i.
Principal investigator: Hozák Pavel
Research years: 2012-2014

FR-TI4/802
Vývoj nových chemických sloučenin využitelných v protinádorové terapii a regenerativní medicíně
Contractor: Institute of Molecular Genetics of the ASCR, v. v. i.
Principal investigator: Bartůněk Petr
Research years: 2012-2015

GA MŠk

EE.2.3.20.0102
Founding of an expert team for the Centre for Phenogenomics
Contractor: Institute of Molecular Genetics of the ASCR, v. v. i.
Principal investigator: Sedláček Radislav
Research years: 2011-2014

LH12202
Analysis and suppression of mechanisms leading to the resistance of cancer cells to TRAIL
Contractor: Institute of Molecular Genetics of the ASCR, v. v. i.
Principal investigator: Anděra Ladislav
Research years: 2012-2014

LK11213
Analysis of genes Pin1 and CRMP2A and their impact on axon growth, branching and regeneration in vitro and in vivo
Contractor: Institute of Molecular Genetics of the ASCR, v. v. i.
Principal investigator: Balaštík Martin
Research years: 2012-2016

ED1.1.00/02.0109
Biotechnology and Biomedicine Centre of the Academy of Sciences and Charles University
Contractor: Institute of Molecular Genetics of the ASCR, v. v. i.; Institute of Physiology of the ASCR, v. v. i.; Institute of Macromolecular Chemistry of the ASCR, v. v. i.
Principal investigator: Hořejší Václav; Paleček Jiří; Brynda Eduard
Research years: 2012-2015

LM2011022
CZ-OPENSCREEN: National Infrastructure for Chemical Biology
Contractor: Institute of Molecular Genetics of the ASCR, v. v. i.
Principal investigator: Bartůněk Petr
Research years: 2012-2015

LK11214
Genetic regulation of embryonic development of the brain and the eye
Contractor: Institute of Molecular Genetics of the ASCR, v. v. i.
Principal investigator: Machoň Ondřej
Research years: 2012-2016

LM2011032
Infrafrontier-CZ/Czech Centre for Phenogenomics as a national centre of „The European infrastructure for phenotyping and archiving of model mammalian genomes“: Integration of the Czech national centre into international network
Contractor: Institute of Molecular Genetics of the ASCR, v. v. i.
Principal investigator: Sedláček Radislav
Research years: 2012-2015

LD12073
Membrane signalosomes of mast cells and basophils - targets for innovative therapies
Contractor: Institute of Molecular Genetics of the ASCR, v. v. i.
Principal investigator: Dráber Petr
Research years: 2012-2014

LH12049
New Genomic Strategy for Rapid Identification of Genes Controlling Development of Infections and Cancer
Contractor: Institute of Molecular Genetics of the ASCR, v. v. i.
Principal investigator: Lipoldová Marie
Research years: 2012-2015

LD12063
New nuclear functions of intermediate filaments
Contractor: Institute of Molecular Genetics of the ASCR, v. v. i.
Principal investigator: Hozák Pavel
Research years: 2012-2014

LE12004
Support of the Czech participation in the pan-European research infrastructure Euro-BioImaging
Contractor: Institute of Molecular Genetics of the ASCR, v. v. i.
Principal investigator: Hozák Pavel
Research years: 2012-2015

LH12143
Cooperative contribution of actin- and myosin-families to the chromatin dynamics and tranion in the cell nucleus
Contractor: Institute of Molecular Genetics of the ASCR, v. v. i.
Principal investigator: Hozák Pavel
Research years: 2012-2014

LK11215
Regulation of active endogenous retroviruses in the mammalian genome
Contractor: Institute of Molecular Genetics of the ASCR, v. v. i.
Principal investigator: Elleder Daniel
Research years: 2012-2016

LH12050
Regulation of microtubule formation in brain cancer cells
Contractor: Institute of Molecular Genetics of the ASCR, v. v. i.
Principal investigator: Dráber Pavel
Research years: 2012-2015

LH12047
The role of alternative splicing in evolution of vertebrate body plan
Contractor: Institute of Molecular Genetics of the ASCR, v. v. i.
Principal investigator: Kozmik Zbyněk
Research years: 2012-2015

EE2.3.30.0027
Founding the Centre of Transgenic Technologies
Contractor: Institute of Molecular Genetics of the ASCR, v. v. i.
Principal investigator: Sedláček Radislav
Research years: 2012-2014

LG12017
Ensuring Participation in Governing Bodies of the European and World Microscopy Societies (EMS, IFSM
Contractor: Institute of Molecular Genetics of the ASCR, v. v. i.
Principal investigator: Hozák Pavel
Research years: 2012-2014

LK21307
C/EBPg in normal hematopoiesis and acute myeloid leukemia: identification of the molecular mechanisms involved in cellular transformation
Contractor: Institute of Molecular Genetics of the ASCR, v. v. i.
Principal investigator: Meritxell Alberich-Jordà
Research years: 2013-2015

LD13015
Microtubules in activated mast cells - targets for innovative therapies
Contractor: Institute of Molecular Genetics of the ASCR, v. v. i.
Principal investigator: Dráber Pavel
Research years: 2013-2014

LG13035
Support of participation in the European Society for Histochemistry
Contractor: Institute of Molecular Genetics of the ASCR, v. v. i.
Principal investigator: Hozák Pavel
Research years: 2013-2015

LH13084
Post-transcriptional control of oocyte-to-zygote transition
Contractor: Institute of Molecular Genetics of the ASCR, v. v. i.
Principal investigator: Svoboda Petr
Research years: 2013-2015

7AMB13AT012
Structural and functional analysis of interaction between calmodulin and plectin isoform 1a
Contractor: Institute of Molecular Genetics of the ASCR, v. v. i.
Principal investigator: Gregor Martin
Research years: 2013-2014

LH14033
Spliceosomal snRNP assembly and surveillance in Drosophila melanogaster
Contractor: Institute of Molecular Genetics of the ASCR, v. v. i.
Principal investigator: Staněk David
Research years: 2014-2016

LH14276
Novel Causative Genes Identification and Functional Study for selected Mendelian Disorders
Contractor: Institute of Molecular Genetics of the ASCR, v. v. i.
Principal investigator: Sedláček Radislav
Research years: 2014-2016

LH14037
Identification of protein complexes associated with genotoxic RNA:DNA hybrids and their role in maintenance of genomic stability
Contractor: Institute of Molecular Genetics of the ASCR, v. v. i.
Principal investigator: Dobrovolná Jana
Research years: 2014-2016

LG14017
Representation of the Czech scientific community in FEBS, IUBMB, EMBC, EMBO, ESBRA and other relevant organizations
Contractor: Institute of Molecular Genetics of the ASCR, v. v. i.
Principal investigator: Pačes Václav
Research years: 2014-2016

GA MZd

NT13271
Fenotypizace T- a B-lymfocytů u imunodeficientních pacientů
Contractor: Institute of Molecular Genetics of the ASCR, v. v. i.
Principal investigator: Brdička Tomáš
Research years: 2012-2015

NT13488
Genomická analýza nádorově asociovaných fibroblastů u nádorů hlavy a krku: podklad pro novou generaci biologické protinádorové terapie
Contractor: Institute of Molecular Genetics of the ASCR, v. v. i.
Principal investigator: Strnad Hynek
Research years: 2012-2015

NT13462
Optimalizace imunoterapie a monitorace minimální reziduální nemoci pomocí průtokové cytometrie u rezistentní akutní lymfoblastické leukémie
Contractor: Institute of Molecular Genetics of the ASCR, v. v. i.
Principal investigator: Otáhal Pavel
Research years: 2012-2015

NT13201
Role angiogeneze v přežití, růstu, šíření a terapeutické odpovědi lymfomu z plášťových buněk (Mantle Cell Lymphoma, MCL)
Contractor: Institute of Molecular Genetics of the ASCR, v. v. i.
Principal investigator: Anděra Ladislav
Research years: 2012-2015

NT13112
Studium protinádorových účinků statinů
Contractor: Institute of Molecular Genetics of the ASCR, v. v. i.
Principal investigator: Strnad Hynek
Research years: 2012-2015

NT14461
Senescence cells elimination in minimal residual tumour disease therapy
Contractor: Institute of Molecular Genetics of the ASCR, v. v. i.
Principal investigator: Reiniš Milan
Research years: 2013-2015

NT14451
New technology for correction of mutations in monogenetic diseases by targeted reparation of mutations using specific nucleases
Contractor: Institute of Molecular Genetics of the ASCR, v. v. i.
Principal investigator: Sedláček Radislav
Research years: 2013-2015

NT14467
Microtubule regulatory proteins as new biomarkers of gliomas
Contractor: Institute of Molecular Genetics of the ASCR, v. v. i.
Principal investigator: Dráber Pavel
Research years: 2013-2015

NT14601
Syncytins as markers of germ line tumors
Contractor: Institute of Molecular Genetics of the ASCR, v. v. i.
Principal investigator: Hejnar Jiří
Research years: 2013-2015

NT14174
Vliv 5-azacytidinu na imunogenetiku a genotoxický stres v léčbě myelodysplastického syndromu
Contractor: Institute of Molecular Genetics of the ASCR, v. v. i.
Principal investigator: Bieblová Jana
Research years: 2013-2015

GA MZe

QJ1210041
Nový typ vakcíny pro tlumení virových onemocnění u drůbeže
Contractor: Institute of Molecular Genetics of the ASCR, v. v. i.; Institute of Microbiology of the ASCR, v. v. i.
Principal investigator: Staněk Ondřej; Hejnar Jiří
Research years: 2012-2016

GA TA ČR

TE01020118
Elektronová mikroskopie
Contractor: Biology Centre of the ASCR, v. v. i.; Institute of Macromolecular Chemistry of the ASCR, v. v. i.; Institute of Scientific Instruments of the ASCR, v. v. i.; Institute of Molecular Genetics of the ASCR, v. v. i.
Principal investigator: Nebesářová Jana; Šlouf Miroslav; Müllerová Ilona; Frank Luděk; Hozák Pavel
Research years: 2012-2019

TA02010212
ReceptorX: Integrated platform for drug discovery and development
Contractor: Institute of Molecular Genetics of the ASCR, v. v. i.
Principal investigator: Bartůněk Petr
Research years: 2012-2015

TA02010797
Labelling of recombinant antibody fragments with use of microfluidic systems
Contractor: Nuclear Physics Institute of the ASCR, v. v. i.; Institute of Molecular Genetics of the ASCR, v. v. i.
Principal investigator: Havránek Vladimír; Sedláček Juraj
Research years: 2012-2014