Kryštof Vladimír

ASEP Publications

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Records found: 25

0396979 - UEB-Q 2014 RIV FR eng J - Journal Article
Dolečková, Iva - Česnek, Michal - Dračínský, Martin - Brynda, Jiří - Voller, J. - Janeba, Zlatko - Kryštof, Vladimír
Synthesis and biological evaluation of guanidino analogues of roscovitine.
European Journal of Medicinal Chemistry. Roč. 62, April 2013 (2013), s. 443-452. ISSN 0223-5234
R&D Projects: GA MŠk 1M0508; GA ČR GAP305/12/0783
Not R&D Projects: GA MŠk(CZ) ED0007/01/01
Institutional Support: CEZ:AV0Z50380511; CEZ:AV0Z40550506
Keywords: 6-Guanidinopurine * Olomoucine * Roscovitine
Subject RIV: CE - Biochemistry
Impact factor: 3.432, year: 2013
Permanent link: http://hdl.handle.net/11104/0224681

0381496 - UEB-Q 2013 RIV IT eng J - Journal Article
Dolečková, Iva - Rárová, L. - Grúz, Jiří - Vondrusová, Magdaléna - Strnad, Miroslav - Kryštof, Vladimír
Antiproliferative and antiangiogenic effects of flavone eupatorin, an active constituent of chloroform extract of Orthosiphon stamineus leaves.
Fitoterapia. Roč. 83, č. 6 (2012), s. 1000-1007. ISSN 0367-326X
Not R&D Projects: GA MŠk(CZ) ED0007/01/01
Institutional Support: CEZ:AV0Z50380511
Keywords: eupatorin * orthosiphon stamineus * flavonoids
Subject RIV: ED - Physiology
Impact factor: 2.231, year: 2012
Permanent link: http://hdl.handle.net/11104/0211953

0399222 - UEB-Q 2014 RIV US eng J - Journal Article
Gucký, T. - Jorda, Radek - Zatloukal, M. - Bazgier, V. - Berka, K. - Řezníčková, Eva - Béres, T. - Strnad, Miroslav - Kryštof, Vladimír
A Novel Series of Highly Potent 2,6,9-Trisubstituted Purine Cyclin-Dependent Kinase Inhibitors.
Journal of Medicinal Chemistry. Roč. 56, č. 15 (2013), s. 6234-6247. ISSN 0022-2623
R&D Projects: GA ČR GAP305/12/0783; GA ČR GD203/09/H046
Not R&D Projects: GA MŠk(CZ) ED0007/01/01; GA MŠk(CZ) ED2.1.00/03.0058; GA MŠk(CZ) EE2.3.20.0017
Institutional Support: CEZ:AV0Z50380511
Keywords: CHRONIC LYMPHOCYTIC-LEUKEMIA * DINACICLIB SCH 727965 * CELL-CYCLE
Subject RIV: ED - Physiology
Impact factor: 5.480, year: 2013
Permanent link: http://hdl.handle.net/11104/0226634

0357898 - UEB-Q 2011 RIV AT eng J - Journal Article
Gucký, Tomáš - Řezníčková, Eva - Džubák, P. - Hajdúch, M. - Kryštof, Vladimír
Synthesis and anticancer activity of some 1,5-diaryl-3-(3,4,5-trihydroxyphenyl)-1H-pyrazolo[4,3-e][1,2,4]triazines.
Monatshefte fur Chemie. Roč. 141, č. 6 (2010), s. 709-714. ISSN 0026-9247
R&D Projects: GA ČR GA204/08/0511; GA ČR GA301/08/1649
Institutional Support: CEZ:AV0Z50380511
Keywords: Pyrazolo[4,3-e][1,2,4]triazine * Anticancer * Cyclin-dependent kinase
Subject RIV: EB - Genetics & Molecular Biology
Impact factor: 1.356, year: 2010
Permanent link: http://hdl.handle.net/11104/0006387

0421049 - UEB-Q 2014 RIV US eng J - Journal Article
Haider, C. - Grubinger, M. - Řezníčková, Eva - Weiss, T.S. - Rotheneder, H. - Miklos, W. - Berger, W. - Jorda, Radek - Zatloukal, M. - Gucký, T. - Strnad, Miroslav - Kryštof, Vladimír - Mikulits, W.
Novel Inhibitors of Cyclin-Dependent Kinases Combat Hepatocellular Carcinoma without Inducing Chemoresistance.
Molecular Cancer Therapeutics. Roč. 12, č. 10 (2013), s. 1947-1957. ISSN 1535-7163
R&D Projects: GA ČR GAP305/12/0783; GA ČR GA301/08/1649
Institutional Support: CEZ:AV0Z50380511
Keywords: PRIMARY HUMAN HEPATOCYTES * SELICICLIB R-ROSCOVITINE * CELL-CYCLE
Subject RIV: CE - Biochemistry
Impact factor: 6.107, year: 2013
Permanent link: http://hdl.handle.net/11104/0227508

0429983 - UEB-Q 2015 RIV US eng J - Journal Article
Holčáková, J. - Müller, P. - Tomasec, P. - Hrstka, R. - Nekulová, M. - Kryštof, Vladimír - Strnad, Miroslav - Wilkinson, G. W. G. - Vojtěšek, B.
Inhibition of Post-Transcriptional RNA Processing by CDK Inhibitors and Its Implication in Anti-Viral Therapy.
PLoS ONE. Roč. 9, č. 2 (2014). ISSN 1932-6203
R&D Projects: GA ČR GBP206/12/G151
Institutional Support: RVO:61389030
Keywords: IMMUNODEFICIENCY-VIRUS TYPE-1 * DEPENDENT KINASE INHIBITORS * LARGE T-ANTIGEN
Subject RIV: EB - Genetics & Molecular Biology
Impact factor: 3.534, year: 2013
Permanent link: http://hdl.handle.net/11104/0234927

0359317 - UEB-Q 2011 RIV GB eng J - Journal Article
Holčáková, J. - Tomašec, P. - Burget, J. J. - Wang, E. C. Y. - Wilkinson, G. W. G. - Hrstka, R. - Kryštof, Vladimír - Strnad, Miroslav - Vojtešek, B.
The inhibitor of cyclin-dependent kinases, olomoucine II, exhibits potent antiviral properties.
Antiviral Chemistry and Chemotherapy. Roč. 20, č. 3 (2010), s. 133-142. ISSN 0956-3202
R&D Projects: GA ČR GA301/08/1649
Institutional Support: CEZ:AV0Z50380511
Keywords: Cyclin-dependent Kinase * Olomoucine II * vaccinia
Subject RIV: EE - Microbiology, Virology
Permanent link: http://hdl.handle.net/11104/0197120

0423094 - UEB-Q 2014 RIV FR eng J - Journal Article
Imramovský, A. - Jorda, Radek - Pauk, K. - Řezníčková, Eva - Dušek, J. - Hanousek, J. - Kryštof, Vladimír
Substituted 2-hydroxy-N-(arylalkyl)benzamides induce apoptosis in cancer cell lines.
European Journal of Medicinal Chemistry. Roč. 68, č. 2013 (2013), s. 253-259. ISSN 0223-5234
R&D Projects: GA ČR GAP305/12/0783; GA ČR GA301/08/1649
Institutional Support: CEZ:AV0Z50380511
Keywords: Diamides * Apoptosis * Cytotoxicity
Subject RIV: CE - Biochemistry
Impact factor: 3.432, year: 2013
Permanent link: http://hdl.handle.net/11104/0229347

0368591 - UEB-Q 2012 RIV JP eng J - Journal Article
Jedinák, L. - Kryštof, Vladimír - Cankař, Petr
THE SYNTHESIS OF SOME DERIVATIVES BASED ON THE 4-BENZYL-1H-PYRAZOLE-3,5-DIAMINE CORE.
Heterocycles. Roč. 88, č. 2 (2011), s. 371-383. ISSN 0385-5414
R&D Projects: GA ČR GA301/08/1649
Institutional Support: CEZ:AV0Z50380511
Keywords: Knoevenagel Condensation * Olefin Reduction * CDK * Hydrazine Cycloaddition * Pyrazole-3,5-diamine
Subject RIV: CE - Biochemistry
Impact factor: 0.999, year: 2011
Permanent link: http://hdl.handle.net/11104/0202890

0382312 - UEB-Q 2013 RIV GB eng J - Journal Article
Jorda, Radek - Paruch, K. - Kryštof, Vladimír
Cyclin-dependent kinase Inhibitors Inspired by Roscovitine: Purine Bioisosteres.
Current Pharmaceutical Design. Roč. 18, č. 20 (2012), s. 2974-2980. ISSN 1381-6128
R&D Projects: GA ČR GAP305/12/0783
Institutional Support: CEZ:AV0Z50380511
Keywords: Cancer * cyclin-dependent kinase * inhibitor
Subject RIV: ED - Physiology
Impact factor: 3.311, year: 2012
http://www.benthamdirect.org/pages/article/1/3177382/cyclin-dependent-kinase-inhibitors-inspired-by-roscovitine-purine-bioisosteres.html
Permanent link: http://hdl.handle.net/11104/0212568

0368592 - UEB-Q 2012 RIV US eng J - Journal Article
Jorda, Radek - Havlíček, Libor - McNae, I. W. - Walkinshaw, M. D. - Voller, Jiří - Šturc, Antonín - Navrátilová, Jana - Kuzma, Marek - Mistrik, M. - Bártek, J. - Strnad, Miroslav - Kryštof, Vladimír
Pyrazolo[4,3-d]pyrimidine Bioisostere of Roscovitine: Evaluation of a Novel Selective Inhibitor of Cyclin-Dependent Kinases with Antiproliferative Activity.
Journal of Medicinal Chemistry. Roč. 54, č. 8 (2011), s. 2980-2993. ISSN 0022-2623
R&D Projects: GA ČR GA301/02/0475; GA ČR GA301/08/1649; GA MŠk ED0007/01/01
Institutional Support: CEZ:AV0Z50380511; CEZ:AV0Z50200510
Keywords: STRUCTURE-GUIDED DESIGN * DNA-END RESECTION * DOWN-REGULATION * R-ROSCOVITINE * CELL-CYCLE
Subject RIV: ED - Physiology
Impact factor: 5.248, year: 2011
Permanent link: http://hdl.handle.net/11104/0202891

0368593 - UEB-Q 2012 RIV GB eng J - Journal Article
Jorda, Radek - Sacerdoti-Sierra, N. - Voller, Jiří - Havlíček, Libor - Kráčalíková, Kateřina - Nowicki, M. W. - Nasereddin, A. - Kryštof, Vladimír - Strnad, Miroslav - Walkinshaw, M. D. - Jaffe, Ch. L.
Anti-leishmanial activity of disubstituted purines and related pyrazolo[4,3-d]pyrimidines.
Bioorganic and Medicinal Chemistry Letters. Roč. 21, č. 14 (2011), s. 4233-4237. ISSN 0960-894X
R&D Projects: GA ČR GA204/08/0511; GA ČR GA301/08/1649
Institutional Support: CEZ:AV0Z50380511
Keywords: Leishmania * Cyclin-dependent kinase * Inhibitor * Therapy
Subject RIV: EE - Microbiology, Virology
Impact factor: 2.554, year: 2011
Permanent link: http://hdl.handle.net/11104/0202892

0359295 - UEB-Q 2011 RIV US eng J - Journal Article
Koledová, Z. - Rašková-Kafková, L. - Calábková, L. - Kryštof, Vladimír - Doležel, P. - Divoký, V.
Cdk2 Inhibition Prolongs G1 Phase Progression in Mouse Embryonic Stem Cells.
Stem Cells and Development. Roč. 19, č. 2 (2010), s. 181-193. ISSN 1547-3287
R&D Projects: GA ČR GA301/08/1649
Institutional Support: CEZ:AV0Z50380511
Keywords: embryonic stem cells * cell cycle * G1 phase
Subject RIV: EB - Genetics & Molecular Biology
Impact factor: 4.791, year: 2010
Permanent link: http://hdl.handle.net/11104/0198840

0382222 - UEB-Q 2013 RIV GB eng J - Journal Article
Kryštof, Vladimír - Baumli, S. - Fürst, R.
Perspective of Cyclin-dependent kinase 9 (CDK9) as a Drug Target.
Current Pharmaceutical Design. Roč. 18, č. 20 (2012), s. 2883-2890. ISSN 1381-6128
R&D Projects: GA ČR GAP305/12/0783
Institutional Support: CEZ:AV0Z50380511
Keywords: Cancer * inflammation * kinase
Subject RIV: ED - Physiology
Impact factor: 3.311, year: 2012
http://www.benthamdirect.org/pages/article/1/3177374/perspective-of-cyclin-dependent-kinase-9-cdk9-as-a-drug-target.html
Permanent link: http://hdl.handle.net/11104/0212510

0359286 - UEB-Q 2011 RIV NL eng J - Journal Article
Kryštof, Vladimír - Uldrijan, S.
Cyclin-dependent kinase inhibitors as anticancer drugs.
Current Drug Targets. Roč. 11, č. 3 (2010), s. 291-302. ISSN 1389-4501
R&D Projects: GA ČR GA204/08/0511; GA ČR GA301/08/1649; GA MŠk(CZ) LC06077
Institutional Support: CEZ:AV0Z50380511
Keywords: CDK * protein kinase * inhibitor
Subject RIV: CE - Biochemistry
Impact factor: 3.061, year: 2010
Permanent link: http://hdl.handle.net/11104/0197097

0359307 - UEB-Q 2012 RIV US eng J - Journal Article
Kryštof, Vladimír - Chamrád, Ivo - Jorda, Radek - Kohoutek, J.
Pharmacological targeting of CDK9 in cardiac hypertrophy.
Medicinal Research Reviews. Roč. 30, č. 4 (2010), s. 646-666. ISSN 0198-6325
R&D Projects: GA ČR GA204/08/0511; GA ČR GA301/09/1832; GA ČR GA301/08/1649
Institutional Support: CEZ:AV0Z50380511
Keywords: P-TEFb * cardiac myocyte * cardiac hypertrophy
Subject RIV: CE - Biochemistry
Impact factor: 10.228, year: 2010
Permanent link: http://hdl.handle.net/11104/0197111

0368596 - UEB-Q 2012 RIV FR eng J - Journal Article
Kryštof, Vladimír - Rárová, Lucie - Liebl, J. - Zahler, S. - Jorda, Radek - Voller, Jiří - Cankař, Petr
The selective P-TEFb inhibitor CAN508 targets angiogenesise.
European Journal of Medicinal Chemistry. Roč. 46, č. 9 (2011), s. 4289-4294. ISSN 0223-5234
R&D Projects: GA ČR GA204/08/0511; GA ČR GA301/08/1649
Institutional Support: CEZ:AV0Z50380511
Keywords: Angiogenesis * Cancer * Transcription * Inhibitor * Cyclin-dependent kinase 9
Subject RIV: CE - Biochemistry
Impact factor: 3.346, year: 2011
Permanent link: http://hdl.handle.net/11104/0202895

0368597 - UEB-Q 2012 RIV NL eng J - Journal Article
Liebl, J. - Kryštof, Vladimír - Vereb, G. - Takacs, L. - Strnad, Miroslav - Pechan, P. - Havlíček, Libor - Zatloukal, Marek - Fuerst, R. - Vollmar, A. M. - Zahler, S.
Anti-angiogenic effects of purine inhibitors of cyclin dependent kinases.
Angiogenesis. Roč. 14, č. 3 (2011), s. 281-291. ISSN 0969-6970
R&D Projects: GA ČR GA204/08/0511; GA ČR GA301/08/1649
Institutional Support: CEZ:AV0Z50380511
Keywords: Angiogenesis * Cdk * Small molecule Cdk inhibitors * Roscovitine
Subject RIV: CE - Biochemistry
Impact factor: 6.063, year: 2011
Permanent link: http://hdl.handle.net/11104/0202896

0388867 - UEB-Q 2013 RIV US eng J - Journal Article
Rárová, L. - Zahler, S. - Liebl, J. - Kryštof, Vladimír - Sedlák, David - Bartůněk, Petr - Kohout, Ladislav - Strnad, Miroslav
Brassinosteroids inhibit in vitro angiogenesis in human endothelial cells.
Steroids. Roč. 77, č. 13 (2012), s. 1502-1509. ISSN 0039-128X
R&D Projects: GA MŠk(CZ) LC06077
Not R&D Projects: GA MŠk(CZ) ED0007/01/01
Institutional Support: CEZ:AV0Z50380511; CEZ:AV0Z50520514; CEZ:AV0Z40550506
Keywords: Angiogenesis * Human umbilical vein endothelial cells * Migration
Subject RIV: EB - Genetics & Molecular Biology
Impact factor: 2.803, year: 2012
Permanent link: http://hdl.handle.net/11104/0217769

0382518 - UEB-Q 2013 RIV GB eng J - Journal Article
Schütznerová, E. - Popa, Igor - Kryštof, Vladimír - Koshino, H. - Trávníček, Zdeněk - Hradil, P. - Cankař, P.
Utilization of DmbNHNH(2) in the synthesis of amino-substituted 4-((3,5-diamino-1H-pyrazol-4-yl)diazenyl)phenols.
Tetrahedron. Roč. 68, č. 21 (2012), s. 3996-4002. ISSN 0040-4020
Not R&D Projects: GA MŠk(CZ) ME09057; GA MŠk(CZ) ED2.1.00/03.0058; GA MŠk(CZ) EE2.3.20.0017
Institutional Support: CEZ:AV0Z50380511
Keywords: 2,4-Dimethoxybenzyl)hydrazine * Dmb-protecting group * Nitrogen heterocycles
Subject RIV: CE - Biochemistry
Impact factor: 2.803, year: 2012
Permanent link: http://hdl.handle.net/11104/0212718

0359316 - UEB-Q 2011 RIV US eng J - Journal Article
Trávníček, Zdeněk - Popa, Igor - Čajan, Michal - Zbořil, R. - Kryštof, Vladimír - Mikulík, J.
The first iron(III) complexes with cyclin-dependent kinase inhibitors: Magnetic, spectroscopic (IR, ES+ MS, NMR, Fe-57 Mossbauer), theoretical, and biological activity studies.
Journal of Inorganic Biochemistry. Roč. 104, č. 4 (2010), s. 405-417. ISSN 0162-0134
R&D Projects: GA MŠk 1M0512; GA ČR GA301/08/1649
Institutional Support: CEZ:AV0Z50380511
Keywords: Iron(III) complexes * 57Fe Mössbauer spectroscopy * CDK inhibition
Subject RIV: CA - Inorganic Chemistry
Impact factor: 3.317, year: 2010
Permanent link: http://hdl.handle.net/11104/0198841

0349823 - UEB-Q 2011 RIV GB eng J - Journal Article
Voller, Jiří - Zatloukal, Marek - Lenobel, René - Doležal, Karel - Béres, Tibor - Kryštof, Vladimír - Spíchal, Lukáš - Niemann, P. - Džubák, P. - Hajdúch, M. - Strnad, Miroslav
Anticancer activity of natural cytokinins: A structure-activity relationship study.
Phytochemistry. Roč. 41, 11-12 (2010), s. 1350-1359. ISSN 0031-9422
R&D Projects: GA ČR GA301/08/1649; GA ČR GA206/09/1284
Institutional Support: CEZ:AV0Z50380511
Keywords: SAR * Cytokinins * Cancer
Subject RIV: FD - Oncology & Hematology
Impact factor: 3.150, year: 2010
Permanent link: http://hdl.handle.net/11104/0189963

0382529 - UEB-Q 2013 RIV US eng J - Journal Article
Wang, K. - Hampson, P. - Hazeldine, J. - Kryštof, Vladimír - Strnad, Miroslav - Pechan, P. - Lord, J. M.
Cyclin-Dependent Kinase 9 Activity Regulates Neutrophil Spontaneous Apoptosis.
PLoS ONE. Roč. 7, č. 1 (2012), "e30128". ISSN 1932-6203
R&D Projects: GA ČR GA301/08/1649
Not R&D Projects: GA ČR(CZ) GA204/08/0511
Institutional Support: CEZ:AV0Z50380511
Keywords: COLONY-STIMULATING FACTOR * PROGRAMMED CELL-DEATH * DOWN-REGULATION
Subject RIV: EB - Genetics & Molecular Biology
Impact factor: 3.730, year: 2012
Permanent link: http://hdl.handle.net/11104/0212729

0395043 - UEB-Q 2014 RIV US eng J - Journal Article
Weitensteiner, S. - Liebl, J. - Kryštof, Vladimír - Havlíček, Libor - Gucký, Tomáš - Strnad, Miroslav - Fuerst, R. - Vollmar, A. - Zahler, S.
Trisubstituted Pyrazolopyrimidines as Novel Angiogenesis Inhibitors.
PLoS ONE. Roč. 8, č. 1 (2013). ISSN 1932-6203
R&D Projects: GA ČR GAP305/12/0783
Not R&D Projects: GA MŠk(CZ) ED0007/01/01
Institutional Support: CEZ:AV0Z50380511
Keywords: CYCLIN-DEPENDENT KINASE-5 * ENDOTHELIAL-CELL MIGRATION * IN-VITRO
Subject RIV: EB - Genetics & Molecular Biology
Impact factor: 3.534, year: 2013
Permanent link: http://hdl.handle.net/11104/0223205

0395483 - UEB-Q 2014 RIV FR eng J - Journal Article
Zatloukal, M. - Jorda, Radek - Gucký, T. - Řezníčková, Eva - Voller, Jiří - Pospíšil, T. - Malínková, V. - Adamcová, H. - Kryštof, Vladimír - Strnad, Miroslav
Synthesis and in vitro biological evaluation of 2,6,9-trisubstituted purines targeting multiple cyclin-dependent kinases.
European Journal of Medicinal Chemistry. Roč. 61, SI (2013), s. 61-72. ISSN 0223-5234
R&D Projects: GA ČR GAP305/12/0783; GA ČR GA301/08/1649
Not R&D Projects: GA MŠk(CZ) ED0007/01/01
Institutional Support: CEZ:AV0Z50380511
Keywords: Cyclin-dependent kinase * Inhibitor * Roscovitine
Subject RIV: EB - Genetics & Molecular Biology
Impact factor: 3.432, year: 2013
Permanent link: http://hdl.handle.net/11104/0223515