Mgr. Tomáš Kubelka, Ph.D.

e-mail: kubelka@uochb.cas.cz
phone: +420 220183108


Born 2. 7. 1983 in Prague (Czech Republic).

Scientific CV:
2003-2006 undergraduate study, Charles University in Prague - Faculty of Science, Bc. S. degree - specialization chemistry in natural sciences (supervisor RNDr. Jan Šarek, Ph.D.)
2004-2007 undergraduate study, Charles University in Prague - Faculty of Science, Bc. S. degree - specialization biology (supervisor Doc. RNDr. Jitka Forstová, CSc.)
2006-2008 undergraduate study, Charles University in Prague - Faculty of Science, M. S. degree - specialization organic chemistry (supervisor RNDr. Jan Šarek, Ph.D.)
2008-2013 PhD study, Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic (supervisor Dr. M. Hocek)
since October 2013 postdoctoral position, TU Munich with Prof. T. Bach

Professional membership:
Czech Chemical Society
IUPAC Affiliate Member

List of publications:

7.	Dhami, K.; Malyshev, D. A.; Ordoukhanian, P.; Kubelka, T.; Hocek, M.; Romesberg, F. E.: "Systematic exploration of a class of hydrophobic unnatural base pairs yields multiple new candidates for the expansion of the genetic alphabet" Nucleic Acids Res. 2014, 42, 10235 – 10244.
6.	Kubelka, T.; Slavětínská, L.; Eigner, V.; Hocek, M.: "Synthesis of 2,6-disubstituted pyridin-3-yl C-2’-deoxyribonucleosides through chemoselective transformations of bromo-chloropyridine C-nucleosides" Org. Biomol. Chem. 2013, 11, 4702-4718.
5.	Kubelka, T.; Slavětínská, L.; Hocek, M.: "Synthesis of Substituted Benzyl Homo-C-ribonucleosides and -nucleotides as Carba Analogues of Phosphoribosylanthranilate" Eur. J. Org. Chem. 2012, 4969–4981.
4.	Chapuis, H.; Kubelka, T.; Joubert, N.; Pohl, R.; Hocek, M.: "Synthesis of 6-Substituted 2(1H)-Pyridon-3-yl C-2'-Deoxyribonucleosides" Eur. J. Org. Chem. 2012, 1759-1767.
3.	Kubelka, T.; Slavětínská, L.; Hocek, M.: "A General Regioselective Approach to 2,4-Disubstituted Pyrimidin-5-yl C-2-Deoxyribonucleosides" Synthesis 2012, 44, 953-965.
2.	Kvasnica, M.; Sarek, J.; Vlk, M.; Budesinsky, M.; Stepanek, O.; Kubelka, T.; Plutnarova, I.: "Study of stereoselectivity of reduction of 18-oxo des-E triterpenoids by sodium borohydride in the presence of cerium chloride" Tetrahedron: Asymmetry 2011, 64, 1011–1020.
1.	Kubelka, T.; Slavětínská, L.; Klepetářová, B.; Hocek, M.: "Synthesis of 2,4-Disubstituted Pyrimidin-5-yl C-2'-Deoxyribonucleosides by Sequential Regioselective Reactions of 2,4-Dichloropyrimidine Nucleosides" Eur. J. Org. Chem. 2010, 2666-2669.

Patents:

1.

Šarek, J.; Hajduch, M.; Svoboda, M.; Nováková, K.; Spáčilová, P.; Kubelka, T.; Biedermann, D.: "Method of preparation of a soluble formulation of water-insoluble pentacyclic and tetracyclic terpenoids, a soluble formulation of a pentacyclic or tetracyclic terpenoid and a pharmaceutical composition containing this soluble formulation" Patent Application PCT/CZ2007/000088.