HomeInstrumentationMS, GC-MS and LC-MSLC-MS Systems

LC-MS Systems


LCQ Fleet

Location:   Department of Mass Spectrometry
Responsible person:   Dr. Josef Cvačka (phone 220 183 303)

LCQ Fleet


LCQ Fleet (Thermo Fisher Scientific) is a 3D ion trap mass spectrometer capable of multiple stage (MSn) analyses. The instrument has an atmospheric pressure ionization source that supports ESI and APCI probes. The optimal mass range of the spectra is 50 - 2000 Da. LCQ Fleet can be coupled to HPLC system for LC/MS applications. Applications include clinical and forensic toxicology, natural product analysis, impurity analysis, metabolite profiling and general analytical chemistry. This instrument was installed in February 2008.


Waters UPLC-MS Acquity

Location:   Research team of Dr. Jiří Šrogl
Responsible person:   Dr. Svatava Voltrová (phone 220 183 392)

Waters UPLC-MS Acquity


The Waters UPLC-MS Acquity combines good resolution, sensitivity, and speed of UltraPerformance technology with single quadrupole MS detection. Rapid polarity switching and multi-mode ionization with simultaneous APCI and ESI for comprehensive compound analyses in a single injection, with ESCiTechnology. Control and data acquisition with MassLynx Software.


HPLC System Waters with Micromass ZQ MS detector

Location:   Research team of Dr. Ivo Starý
Responsible person:   Dr. Jiří Rybáček (phone 220 183 226)

HPLC System Waters with Micromass ZQ MS detector


This state-of-art HPLC-MS System Waters comprises Waters 515 HPLC pump, Knauer HPLC pump, Waters Micromass ZQ MS detector, Waters 2487 Dual λ absorbance system, Waters 2525 binary gradient module, Waters 2420 ELS detector, Waters 2267 sample manager and Water column fluidics organiser.


LC-MS System Waters

Location:   Research team of Dr. Ivan Rosenberg
Responsible person:   Dr. Eva Zborníková (phone 220 183 457)

LC-MS System Waters


Standard LC-MS system for analytical/semipreparative work comprises Waters 515 HPLC pump, Waters Micromass ZQ MS detector, Waters 600 controller, Waters 2998 photodiode array (PDA) detector and Waters sample manager.


LC-MS System Waters Alliance

Location:   Biochemical Pharmacology of Antimetabolites (Dr. Helena Mertlíková-Kaiserová)
Responsible person:   Dr. Helena Mertlíková-Kaiserová (phone 220 183 114)

LC-MS System Waters


LC-MS system for analytical/semipreparative work comprises Waters 2795 separations module, Waters Micromass ZQ MS detector, Waters 2475 mullti fluorescence detector and Waters 2996 photodiode array (PDA) detector.


3× LCQ / LCQ Advantage

Location:   Department of Mass Spectrometry
Responsible person:   Dr. Josef Cvačka (phone 220 183 303)

LCQ Advantage


LCQ (ThermoFisher Scientific) ion-trap mass spectrometers for ion-reactivity studies. In one instrument, a modified inlet system allows the introduction of various samples in the ionization as well as the reaction regions.

Parameters
instrument type: tandem mass spectrometer on ion-trap basis
ionization methods: electrospray ionization, atmospheric pressure chemical ionization
mass range: from m/z 50 up to m/z 2000 (extended up to m/z 4000)
resolution: m/dm = ca. 1500 in standard operation