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Bioorganic and Medicinal Chemistry
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Michal Hocek
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Projects
Projects
Development of novel methodologies for the synthesis of modified nucleobases and nucleosides
Medicinal chemistry of analogues of nucleobases and nucleosides
Desing and synthesis of novel C-nucleosides for chemical biology
Synthesis of modified nucleoside triphosphates and polymerase construction of functionalized nucleic acids
Novel redox or fluorescent DNA labeling for bioanalytical applications
Chemical biology of base-modified nucleic acids