2015

Petr Jansa, Antonín Holý, Martin Dračínský, Viktor Kolman, Zlatko Janeba, Eva Kmoníčková, Zdeněk Zídek
Synthesis and structure–activity relationship studies of polysubstituted pyrimidines as inhibitors of immune-activated nitric oxide production
Medicinal Chemistry Research
DOI: 10.1007/s00044-014-1285-5 (published online)

Wai Soon Eng, Dana Hocková, Petr Špaček, Zlatko Janeba, Nicholas P. West, Kyra Woods, Lieve Naesens, Dianne Therese Keough, and Luke W. Guddat
The first crystal structures of Mycobacterium tuberculosis 6-oxopurine phosphoribosyltransferase: Complexes with GMP and pyrophosphate and with acyclic nucleoside phosphonates whose prodrugs have antituberculosis activity.
Journal of Medicinal Chemistry, 2015
DOI: 10.1021/acs.jmedchem.5b00611 (accepted)

Dianne T. Keough, Dana Hocková, Zlatko Janeba, Tzu-Hsuan Wang, Lieve Naesens, Michael D. Edstein, Marina Chavchich, and Luke W. Guddat
Aza-acyclic Nucleoside Phosphonates Containing a Second Phosphonate Group As Inhibitors of the Human, Plasmodium falciparum and vivax 6-Oxopurine Phosphoribosyltransferases and Their Prodrugs As Antimalarial Agents
Journal of Medicinal Chemistry 58: 827-846, 2015
DOI: 10.1021/jm501416t

Dana Hocková, Šářka Rosenbergová, Petra Ménová, Ondra Páv, Radek Pohl, Pavel Novák, Ivan Rosenberg
N-Branched acyclic nucleoside phosphonates as monomers for the synthesis of modified oligonucleotides
Organic & Biomolecular Chemistry 13: 4449-4458, 2015
DOI: 10.1039/C4OB02265C