Morning session - chair: Pavlína Řezáčová |
| 9:00–9:15 |
Alexander Wlodawer (Head of the IOCB International Advisory Board
Opening remarks
|
| 9:15–9:55 |
Manfred Weiss (Helmholtz-Centrum Berlin, Germany)
Crystallographic fragment screening at the HZB-MX beamlines |
| 9:55–10:20 |
Evžen Bouřa (Institute of Organic Chemistry and Biochemistry, Prague)
Phosphatidylinositol 4-kinases - the (structural) biology
|
| 10:20-10:45 |
Coffee break |
| 10:45-11:25 |
Tobias Madl (Technische Universität München, Germany)
Integration of NMR and complementary techniques for structural studies of large protein complexes
|
| 11:25-11:50 |
Aleš Hnízda (Institute of Organic Chemistry and Biochemistry, Prague)
Relapsed ALL-specific mutations revealed allosteric network in cytosolic purine 5´-nucleotidase
|
| 11:50-12:30 |
Richard Štefl (Central European Institute of Technology, Brno)
Mechanisms of recruitment and displacement of processing factors by RNA Polymerase II
|
| 12:30-13:30 |
Lunch break |
Afternoon session - chair: Alexander Wlodawer |
| 13:30-14:10 |
Alistair Henry (UCB Pharma, United Kingdom)
What can antibodies teach us about PPI opportunities?
|
| 14:10-14:50 |
Václav Veverka (Institute of Organic Chemistry and Biochemistry, Prague)
Extending the LEDGF/p75 interactome
|
| 14:50-15:15 |
Coffee break |
| 15:15-15:40 |
Kvido Stříšovský (Institute of Organic Chemistry and Biochemistry, Prague)
Integrated structural enzymology of intramembrane proteolysis
|
| 15:40-16:20 |
Richard Bayliss (University of Leicester, United Kingdom)
The Ys and the wherefores of kinase autoinhibition
|
| 16:20-16:35 |
Zdeněk Hostomský (Director of IOCB)
Final remarks
|
| 16:35-18:00 |
Facility tours |
