EE2.3.20.0274 MSM
Human resources for neurosciences in the Hradec Králové and Ústí Regions
Contractor: Institute of Experimental Medicine AS CR, v.v.i.
Principal investigator: prof. Eva Syková, MD, DSc, FCMA
Duration: 2012–2015
EE2.3.30.0018 MSM
Development of Research Teams of IEM AS CR for the BIOCEV
Contractor: Institute of Experimental Medicine AS CR, v.v.i.
Principal investigator: Prof. Eva Syková, MD, DSc, FCMA
Duration.: 2012–2015
FR-TI3/521 MPO
Technology of new magnetic nanoparticles for diagnostics and therapy in oncology
Contractor: SYNPO, a.s.
Project participant: Institute of Experimental Medicine AS CR, v.v.i., Institut of Physics AS CR,v.v.i., Institute of Chemical Technology in Prague
Investigator: Assoc. Prof. Pavla Jendelová, PhD
Duration: 2011–2015
GAP205/12/0720 GAO
Role of membrane potential in the lateral microdomain organization of the plasma membrane
Contractor: Charles University, Mathematics and Physics Faculty
Principal investigator: Assoc. Prof. Petr Heřman, PhD
Project participant: Institute of Experimental Medicine AS CR, v.v.i.
Investigator: Jan Malínský, PhD
Duration: 2012–2014
GAP301/11/1568 GAO
Cellular aspects of transplantation tolerance
Contractor: Institute of Clinical and Experimental Medicine
Principal investigator: Prof. Ondřej Viklický, MD, PhD
Project participant: Institute of Experimental Medicine AS CR, v.v.i.
Investigator: Prof. Vladimír Holáň, DSc, PhD
Project participant: Institute of Molecular Genetics AS CR, v.v.i.
Duration: 2011–2014
GAP301/11/2418 GAO
Using 13C and proton MR spectroscopy to study the role of fatty acid transport and accumulation in tissues in the pathogenesis of insulin resistance
Contractor: Institute of Experimental Medicine AS CR, v.v.i.
Principal investigator: Ivan Voříšek, PhD
Project participant: Institute of Clinical and Experimental Medicine
Investigator: Ludmila Kazdová, PhD
Duration: 2011–2015
GAP301/12/1734 GAO
Analysis of role of genetic factors in pancreatic cancer risk and prognosis
Contractor: State Health Institute Prague
Principal investigator: Pavel Souček, PhD
Project participant: Institute of Clinical and Experimental Medicine
Investigator: Assoc. Prof. Eva Honsová, MD, PhD
Project participant: University Hospital Brno
Investigator: Prof. Zdeněk Kala, MD, PhD
Project participant: Institute of Experimental Medicine AS CR, v.v.i.
Investigator: Procházka Pavel, PhD
Duration: 2012–2016
GAP302/11/0146 GAO
Role of MARVEL domain containing proteins in the geneticly encoded stress protection
Contractor: Institute of Experimental Medicine AS CR, v.v.i.
Principal investigator: Jan Malínský, PhD
Duration: 2011–2014
GAP303/11/0131 GAO
Ectopic release of glycine – physiological role and mechanism
Contractor: Institute of Experimental Medicine AS CR, v.v.i.
Principal investigator: Michaela Králíková – Havlíčková, PhD
Duration: 2011–2015
GAP303/11/2378 GAO
Changes in the extracellular space diffusion parameters during the development of brain edema and the role of aquaporin water-transporting proteins
Contractor: Institute of Experimental Medicine AS CR, v.v.i.
Principal investigator: Ivan Voříšek, PhD
Duration: 2011–2016
GAP303/12/0172 GAO
Structure-activity relationship (SAR) study of immunosuppressive effects of pyrimidine analogues
Contractor: Institute of Experimental Medicine AS CR, v.v.i.
Principal investigator: Zdeněk Zídek, DSc, PhD
Project participant: Institute of Organic Chemistry and Biochemistry AS CR, v.v.i.
Investigator: Zlatko Janeba, PhD
Duration: 2012–2016
GAP303/12/0535 GAO
Mechanisms of the anti-inflammatory effects of commensal and probiotic akteria and their role in metabolism and drug pharmacokinetics
Contractor: Institut of Microbiology AS CR, v.v.i.
Principal investigator: Tomáš Hudcovic, PhD
Project participant: Institute of Experimental Medicine AS CR, v.v.i.
Investigator: Assoc. Prof. Eva Kmoníčková, PhD
Project participant: Palacký University Olomouc / Faculty of Medicine
Investigator: Assoc. Prof. Eva Anzenbacherová, PhD
Duration: 2012–2016
GAP303/12/0855 GAO
Polydendrocyte function in regeneration after ischemic brain injury – the role of Wnt signaling pathway
Contractor: Institute of Experimental Medicine AS CR, v.v.i.
Principal investigator: Anděrová Miroslava, PhD
Duration: 2012–2015
GAP303/12/1347 GAO
Mechanisms underlying complex sound processing in the neuronal assemblies in the auditory system
Contractor: Institute of Experimental Medicine AS CR, v.v.i.
Principal investigator: Prof. Josef Syka, MD, DSc, FCMA
Duration: 2012–2016
GAP304/10/0326 GAO
Autologous mesenchymal stem cells in rotator cuff repair enhancement – preclinical and prospective randomized clinical study
Contractor: Charles University, 2nd Faculty of Medicine
Principal investigator: Assoc. Prof. Tomáš Trč, PhD, MBA
Project participant: Institute of Experimental Medicine AS CR, v.v.i.
Investigator: Prof. Eva Syková, MD, DSc, FCMA
Duration: 2010–2015
GAP304/11/0184 GAO
The potential of mesenchymal stem cells in the treatment of Alzheimer’s
Contractor: Charles University, 2nd Faculty of Medicine
Principal investigator: Prof. Eva Syková, MD, DSc, FCMA
Project participant: Institute of Experimental Medicine AS CR, v.v.i.
Investigator: Assoc. Prof. Pavla Jendelová, PhD
Duration: 2011–2016
GAP304/11/0189 GAO
The use of stem cells in the treatment of amyotrophic lateral sclerosis
Contractor: Institute of Experimental Medicine AS CR, v.v.i.
Principal investigator: Assoc. Prof. Pavla Jendelová, PhD
Project participant: Charles University, 2nd Faculty of Medicine
Investigator: Aleš Homola, MD, PhD
Duration: 2011–2014
GAP304/11/0653 GAO
Targeted differentiation and transdifferentiation of limbal and mesenchymal stem cells and their therapeutic applications in preclinical models
Contractor: Institute of Experimental Medicine AS CR, v.v.i.
Principal investigator: Prof. Vladimír Holáň, DSc, PhD
Project participant: Institute of Molecular Genetics AS CR, v.v.i.
Duration: 2011–2014
GAP304/11/1418 GAO
Differentiation of human embryonic stem cells into odontogenic lineages
Contractor: Masaryk University / Faculty of Medicine
Principal investigator: Assoc. Prof. Aleš Hampl, MVD, PhD
Project participation: Institute of Animal Physiology and Genetics AS CR, v.v.i.
Investigator: Prof. Eva Matalová, PhD
Project participation: Institute of Experimental Medicine AS CR, v.v.i.
Duration: 2011–2014
GAP304/12/1342 GAO
Pathological changes in the central auditory system accompanying aging
Contractor: Institute of Experimental Medicine AS CR, v.v.i.
Principal investigator: Jiří Popelář, PhD
Duration: 2012–2016
GAP304/12/1370 GAO
Superparamagnetic iron-oxide nanoparticles for cellular imaging and their effect on genotoxicity, cytotocixity and stem cell differentiation
Contractor: Institute of Experimental Medicine AS CR, v.v.i.
Principal investigator: Assoc. Prof. Pavla Jendelová, PhD
Duration: 2012–2015
GAP304/12/1585 GAO
Molecular DNA repair characteristics in CRC tumor tissue
Contractor: Charles University, 1st Faculty of Medicine
Principal investigator: Pavel Vodička, MD, PhD
Project participant: Thomayer Hospital
Investigator: Ludmila Lipská, MD, PhD
Project participant: Institute of Experimental Medicine AS CR, v.v.i.
Investigator: Ludmila Vodičková, MD, PhD
Project participant: State Health Institute Prague
Investigator: Simona Šůsová, MSc
Project participant: Institute of Biotechnology AS CR, v.v.i.
Investigator: Vlasta Korenková, PhD
Research years: 2012–2015
GAP305/12/1766 GAO
Rudiments in the mouse model of tooth development
Contractor: Institute of Experimental Medicine AS CR, v.v.i.
Principal investigator: Hovořáková Mária, PhD
Research years: 2012–2016
GAP503/11/0142 GAO
Genotoxic and non-genotoxic mechanisms involved in carcinogenicity of complex
mixtures of air pollutants: toxicogenomic approach
Contractor: Institute of Experimental Medicine AS CR, v.v.i.
Principal investigator: Jan Topinka, DSc, PhD
Project participant: Veterinary Research Institute
Investigator: Miroslav Machala, PhD
Duration: 2011–2015
GA13-00939S GAO
The treatment of chronic spinal cord injury using stem cells and enzymes in combination with polymer scaffolds
Contractor: Institute of Experimental Medicine AS CR, v.v.i.
Principal investigator: Assoc. Prof. Pavla Jendelová, PhD
Project participant: Institute of Macromolecular Chemistry AS CR, v.v.i.
Investigator: Martin Přádný, PhD
Project participant: Charles University, 2nd Faculty of Medicine
Investigator: Assoc. Prof. Lýdia Vargová, MD, PhD
Duration: 2013–2016
GA13-01438S GAO
Mechanisms of toxicity of biofuel particulate emissions
Contractor: Institute of Experimental Medicine AS CR, v.v.i.
Principal investigator: Jan Topinka, DSc, PhD
Project participant: Institute of Analytical Chemistry AS CR, v.v.i.
Investigator: Pavel Mikluška, PhD
Project participant: Czech Technical University in Prague
Investigator: Michal Vojtíšek, PhD
Duration: 2013–2015
GA13-02154S GAO
Gene expression profiling and functional characterization of glial cell subpopulations following ischemic brain injury
Contractor: Institute of Biotechnology AS CR, v. v. i.
Principal investigator: Prof. Mikael Kubista, PhD
Project participant: Institute of Experimental Medicine AS CR, v.v.i.
Investigator: Miroslava Anděrová, PhD
Duration: 2013–2016
GA13-07996S GAO
Molecular mechanisms responsible for generating cellular diversity in the inner ear
Contractor: Institute of Biotechnology AS CR, v. v. i.
Principal investigator: Gabriela Pavlínková, PhD
Project participant: Institute of Experimental Medicine AS CR, v.v.i.
Investigator: Prof. Josef Syka, MD, DSc, FCMA
Duration: 2013–2016
GA13-11867S GAO
The role of brain link proteins for formation and maintenance of perineuronal nets
Contractor: Charles University, 2nd Faculty of Medicine
Principal investigator: Assoc. Prof. Lýdia Vargová, MD, PhD
Project participant: Institute of Experimental Medicine AS CR, v.v.i.
Investigator: Jiří Popelář, PhD
Duration: 2013–2015
GA13-13458S GAO
Impact of air pollution to genome of newborns
Contractor: Institute of Experimental Medicine AS CR, v.v.i.
Principal investigator: Šrám Radim, MD, DSc
Project participant: University of South Bohemia in České Budějovice, Health and Social Studies
Investigator: Miloš Velemínský, MD, PhD
Project participant: University of Chemical Industry in Prague
Investigator: Assoc. Prof. Jana Pulkrabová, PhD
Duration: 2013–2016
GA14-03540S GAO
Autologous cell based therapy for ischemic diabetic wounds: preclinical and clinical trial
Contractor: Institute of Clinical and Experimental Medicine
Principale investigator: Robert Bem, MD, PhD
Project participant: Institute of Experimental Medicine AS CR, v.v.i.
Investigator: Prof. Eva Syková, MD, DSc, FCMA
Duration: 2014–2016
GA14-12580S GAO
Treatment of severe ocular surface injuries using limbal and mesenchymal stem cells
Contractor: Institute of Experimental Medicine AS CR, v.v.i.
Principal investigator: Prof. Vladimír Holáň, DSc, PhD
Project participant: Lexum, a.s.
Investigator: Prof. Martin Filipec, MD, PhD
Project participant: Charles University, the Faculty of Science
Investigator: Magdaléna Krulová, PhD
Duration: 2014–2016
GA14-14961S GAO
Spinal cord injury reconstruction using surface-modified biodegradable hydrogels with oriented pores seeded with mesenchymal stem cells
Contractor: Institute of Experimental Medicine AS CR, v.v.i.
Principal Investigator: Aleš Hejčl, MD, PhD
Project participant: Institute of Macromolecular Chemistry AS CR, v. v.i.
Investigator: Hana Macková, PhD
Duration: 2014–2016
GA14-28334S GAO
Molecular mechanism of GABA B receptor regulation by KCTD proteins
Contractor: Institute of Experimental Medicine AS CR, v.v.i.
Principal investigator: Michaela Králíková – Havlíčková, PhD
Duration: 2014–2016
GA14-34077S GAO
Calcium homeostasis in central and peripheral oxytocin and vasopressin neurons: repercussions in osmoregulation, pregnancy, lactation and nociception
Contractor: Institute of Experimental Medicine AS CR, v.v.i.
Principal investigator: Prof. Govindan Dayanithi, PhD
Duration: 2014–2016
GBP304/12/G069 GAO
Project of excellence in the field of neuroscience
Contractor: Institute of Physiology AS CR, v. v. i.
Principal investigator: Ladislav Vyklický Jr., MD, DSc
Project participant: The National Institute of Mental Health
Investigator: Daniela Řípová, PhD
Project participant: Institute of Experimental Medicine AS CR, v.v.i.
Investigator: Prof. Josef Syka, MD, DSc, FCMA
Project participant: Charles University, 2nd Faculty of Medicine
Investigator: Miroslava Anděrová, PhD
Duration: 2012–2018
GBP503/12/G147 GAO
Centre of Studies toxic properties of nanoparticles
Contractor: Veterinary Research Institute, v.v.i.
Principal investigator: Miroslav Machala, PhD
Project participant: Institute of Chemical Process Fundamentals AS CR, v. v. i.
Investigator: Pavel Moravec, PhD
Project participant: Institute of Animal Physiology and Genetics AS CR, v. v. i.
Investigator: Assoc. Prof. Omar Šerý, PhD
Project participant: Institute of Analytical Chemistry AS CR, v. v. i.
Investigator: Zbyněk Večeřa, PhD
Project participant: Institute of Experimental Medicine AS CR, v.v.i.
Investigator: Jan Topinka, DSc, PhD
Project participant: Charles University in Prague, the Faculty of Science
Investigator: Jan Hovorka, PhD
Duration: 2012–2018
GB14-37368G GAO
Centre of orofacial development and regeneration
Contractor: Institute of Experimental Medicine AS CR, v.v.i.
Principal investigator: Renata Peterková, MD, PhD
Project participant: Institute of Animal Physiology an Genetics AS CR, v. v. i.
Investigator: Prof. Eva Matalová, PhD
Project participant: Charles University in Prague, 1st Faculty of Medicine
Investigator: Prof. Zdeněk Broukal, MD, PhD
Project participant: Masaryk University, Faculty of Medicine
Investigator: Prof. Jiří Vaněk, MD, PhD
Duration: 2014–2018
GCP303/11/J005 GAO
Neural remodeling after early sound exposures
Contractor: Institute of Experimental Medicine AS CR, v.v.i.
Principal investigator: Prof. Josef Syka, MD, DSc, FCMA
Duration: 2011–2014
GP13-15031P GAO
The influence of anti-inflamatory agents in combination with mesenchymal stem cells on the development of traumatic spinal cord lesions in the rat
Contractor: Institute of Experimental Medicine AS CR, v.v.i.
Principal investigator: Machová-Urdzíková Lucia, MD, PhD
Duration: 2013–2015
LD14002 MSM
Toxic effects of nanomaterials as a function of their structure and physicochemical properties
Contractor: Institute of Experimental Medicine AS CR, v.v.i.
Principal investigator: Topinka Jan, DSc, PhD
Duration: 2014–2016
LD14050 MSM
Genetic and functional determinants of colorectal cancer and prospects to individualised therapy
Contractor: Institute of Experimental Medicine AS CR, v.v.i.
Principal investigator: Vodička Pavel, MD, PhD
Duration: 2014 –2017
LH12024 MSM
Determining the molecular aspects of spinal cord injury, regeneration, stem cell therapy and treatment with anti-inflammatory compounds
Contractor: Institute of Experimental Medicine AS CR, v.v.i.
Principal investigator: Assoc. Prof. Pavla Jendelová, PhD
Duration: 2012–2015
LH13061 MSM
The role of Ganoderma Lucidum in the regulation of NFkappaB-dependent DNA repairproteasome interactions in colorectal carcinogenesis
Contractor: Institute of Experimental Medicine AS CR, v.v.i.
Principal investigator: Vodička Pavel, MD, PhD
Duration: 2013–2015
LO1309 MSM
Cell Therapy and Tissue Repair
Contractor: Institute of Experimental Medicine AS CR, v.v.i.
Principal investigator: Kubinová Šárka, PhaermD, PhD
Duration: 2014–2019
NT12025 MZ
Molecular-biological and histopathological characteristics of tumor infiltrating lymphocytes as instrument of prediction of risk of early colorectal cancer recurrence
Contractor: Charles University in Prague, Faculty of Medicine in Pilsen
Principal investigator: Petr Novák, MD
Project participant: Institute of Experimental Medicine AS CR, v.v.i.
Investigators: Pavel Vodička, MD, PhD
Project participant: University Hospital in Pilsen
Investigator: Václav Liška, MD, PhD
Project participant: State Health Institute Prague
Investigators: Pavel Souček, PhD
NT12459 MZ
Possibilities of hearing preservation in patients with vestibular schwannoma
Contractor: Institute of Experimental Medicine AS CR, v.v.i.
Principal investigator: Prof. Josef Syka, MD, DSc, FCMA
Project participant: University Hospital Motol
Investigators: Prof. Jan Betka, MD
Duration: 2011–2015
NT13424 MZ
MiR137 and its influence on the production of mucin as a potential tool in early diagnosis of colorectal cancer or colorectal cancer relapse
Contractor: Thomayer Hospital
Principal investigators: Miroslav Levý, MD, PhD
Project participant: Institute of Experimental Medicine AS CR, v.v.i.
Investigator: Vodička Pavel, MD, PhD
Duration: 2012–2015
NT13477 MZ
The use of the synthetic biomaterials in the treatment of the extensive skeletal defects in revision total hip arthroplasty
Contractor: Charles University in Prague, Faculty of Medicine in Hradec Kralové
Principale investigators: Pavel Šponer, MD, PhD
Project participant: University Hospital in Hradec Králové
Investigators: Assoc. Prof. Karel Urban, MD, PhD
Project participant: Institute of Experimental Medicine AS CR, v.v.i.
Investigators: Prof. Eva Syková, MD, DSc, FCMA
Duration: 2012–2015
NT13770 MZ
Examination of DNA instability in gametes, embryos and somatic cells following oncological therapy for improvement of reproductive success in treated patients
Contractor: University Hospital Motol
Investigators: Prof. Milan Macek Jr., MD, DSc
Project participant: Institute of Experimental Medicine AS CR, v.v.i.
Investigator: Božena Novotná, PhD
Duration: 2012–2015
NT14056 MZ
Molecular and genetic biomarkers of ovarian cancer pathogenesis and resistence
Contractor: State Health Institute Prague
Principale contractor: Radka Václavíková, PhD
Project participant: University Hospital Motol
Investigator: Prof. Lukáš Rob, MD, PhD
Project participant: Institute of Experimental Medicine AS CR, v.v.i.
Investigator: Vodička Pavel, MD, PhD
Duration: 2013–2015
NT14102 MZ
A role of B lymphocytes in immune reactions after kidney transplantation
Contractor: Institute of Clinical and Experimental Medicine
Principal investigator: Prof. Ondřej Viklický, MD, PhD
Project participant: Institute of Experimental Medicine AS CR, v.v.i.
Investigator: Prof. Vladimír Holáň, DSc, PhD
Research duration: 2013–2015
NT14329 MZ
Evaluation of changes of molecular-biologic factors and their importance in prognosis of relapsing colorectal cancer after radical surgical treatment
Contractor: Charles University in Prague, Faculty of Medicine in Pilsen
Principal investigator: Václav Liška, MD, PhD
Project participant: University Hospital in Pilsen
Investigators: Petr Novák, MD
Project participant: Institute of Experimental Medicine AS CR, v.v.i.
Investigators: Pavel Vodička, MD, PhD
Project participant: State Health Institute Prague
Investigator: Pavel Souček, PhD
Duration: 2013–2015
TA04010449 TAO
Low temperature plasma in medicine
Contractor: FOTON, Ltd
Principal investigators: Jaroslav Moravec, MSc; Jiří Horáček; Tomáš Petráček, MSc
Project participant: SINDAT, Ltd
Investigator: Daniel Bezděk, MSc
Project participant: L.E.T. Optomechanika Praha, Ltd
Investigator: Tomáš Fejt, MSc
Project participant: Institute of Experimental Medicine AS CR, v.v.i.
Investigator: PharmD, Šárka Kubinová, PhD
Project participant: Institute of Physics AS CR, v.v.i.
Investigator. Alexandr Dejneka, PhD
TE01020028 TAO
Centre for Development of Original Drugs
Contractor: Institute of Organic Chemistry and Biochemistry AS CR, v. v. i.
Principal investigator: Havlas Zdeněk, DSc
Project participant: QUINTA-ANALYTICA, Ltd
Investigator: Assoc. Prof. Martin Valchář, PhD
Project participant: MediTox, Ltd
Investigator: Jan Zábský, MBA
Project participant: IOCB TTO, Ltd
Investigator: Assoc. Prof. Martin Fusek, PhD
Project participant: APIGENEX, Ltd
Investigator: Miroslav Havránek, PhD
Project participant: Institute of Physiology AS CR, v. v. i
Investigator: Ladislav Vyklický, MD, DSc
Project participant: Institute of Experimental Medicine AS CR, v.v.i.
Investigator: Zdeněk Zídek, DSc, PhD
Project participant: Palacký University Olomouc, Faculty of Medicine
Investigator: Assoc. Prof. Marián Hajdúch, MD, PhD
Project participant: Institute of Chemical Technology in Prague, Faculty of Chemical Engineering
Investigator: Prof. Vladimír Král, DSc
Duration: 2012–2019
TG 01010135 TAO
Commercialization of R & D programs in applied research, experimental development and innovation GAMA
Contractor: Institute of Experimental Medicine AS CR, v.v.i.
Principal investigator: Prof. Eva Syková, MD, DSc, FCMA
Duration: 2014–2019
7F14057 MSM
Biomaterials and stem cells in the treatment of stroke and spinal cord injury
Contractor: Institute of Experimental Medicine AS CR, v.v.i.
Investigator: Assoc. Prof. Pavla Jendelová, PhD
Project participant: Norges teknisk-naturvitenskapelige universitet
Investigator: Ioanna Sandvig, PhD
Duration: 2014–2017
Prague City Hall, Operational Programme Prague for competition (OPPK)
CZ 2.16/3.1.00/21527
Advanced imaging of living tissues
Contractor: Institute of Experimental Medicine AS CR, v.v.i.
Principal investigator: Jan Malinský, PhD
Project summary: The objective of the project was to purchase new microscope technology to enhacement competition of the biomedical research carried out at the Institute.
Duration: 01–09/2014
Prague City Hall, Operational Programme Prague for competition (OPPK)
CZ.2.16/3.1.00/21528
Research centre for genomics and proteomics
Contractor: Institute of Experimental Medicine AS CR, v.v.i.
Principal investigator: Radim Šrám, MD, DSc
Project summary: The objective of the project was to purchase new technical research equipment for the research of genomics and proteomics
Duration: 01–09/2014
