master studies at Faculty of Sciences, Masaryk University, Brno
2001 - dosud
researcher, Laboratory of Cell Regeneration and Plasticity, IAPG AS CR, Libechov
2001 - 2007
PhD studies of developmental biology at Faculty of Science, Charles University, Prague
PhD thesis: The minipig as animal model in biomedical stem cell research
Specialization:
The use of porcine tissue specific stem cells (neural and mesenchymal stem cells) for cell therapies of CNS disorders. Preparation of porcine iPS cells and creation of porcine transgenic model of Huntington’s disease.
Dedifferentiation of the pig fetal and adult stem cells with lentiviral vectors for specific transcription factors. Support of the international cooperation project, AS CR M200450971
Societies:
2008
EHDN (European Huntington´s Disease Network)
Internship abroad:
Feb-Mar 2003
Takashi Nagai’s lab, Embryonic Technology Laboratory, National Institute of Agrobiological Sciences, Tsukuba, Japan, pig oocyte and embryo micromanipulation, SCNT
Sept-Oct 2004
Ouredniks lab, Iowa State University, Ames, USA, histology of porcine CNS
Aug 2007
Marian DiFiglia’s lab, Massachusetts General Hospital, Boston, USA, CNS histology, immunodetection of huntingtin in brain tissue
Sep-Dec 2009
Tom Burdon’s lab, Roslin Institute, Scotland, UK, preparation of porcine iPS cells
Publications:
2011
Devine, Michael J.; Ryten, Mina; Vodicka, Petr; Thomson, Alison J.; Burdon, Tom; Houlden, Henry; Cavaleri, Fatima; Nagano, Masumi; Drummond, Nicola J.; Taanman, Jan-Willem; Schapira, Anthony H.; Gwinn, Katrina; Hardy, John; Lewis, Patrick A., and Kunath, Tilo. (2011) Parkinson's disease induced pluripotent stem cells with triplication of the +α-synuclein locus. Nature Communications [10.1038/ncomms1453] ; (2) 440.
Kepkova KV, Vodicka P, Toralova T, Lopatarova M, Cech S, Dolezel R, Havlicek V, Besenfelder U, Kuzmany A, Sirard MA, Laurincik J, Kanka J. (2011) Transcriptomic analysis of in vivo and in vitro produced bovine embryos revealed a developmental change in cullin 1 expression during maternal-to-embryonic transition. Theriogenology; Jun;75(9):1582-95.
2010
Usvald D, Vodicka P, Hlucilova J, Prochazka R, Motlik J, Strnadel J, Kucharova K, Johe K, Marsala S, Scadeng M, Kakinohana O, Navarro R, Santa M, Hefferan MP, Yaksh TL, Marsala M. (2010) Analysis of dosing regimen and reproducibility of intraspinal grafting of human spinal stem cells in immunosuppressed minipigs. Cell Transplant.; 19(9):1103-22
Studenovská H, Vodička P, Proks V, Hlučilová J, Motlík J, Rypáček F. (2010) Synthetic poly(amino acid) hydrogels with incorporated cell-adhesion peptides for tissue engineering. J Tissue Eng Regen Med.; Aug;4(6):454-63
2008
Skalnikova H, Vodicka P, Pelech S, Motlik J, Gadher SJ, Kovarova H. (2008) Protein signaling pathways in differentiation of neural stem cells. Proteomics. Nov; 8(21):4547-59.
Skalnikova H, Vodicka P, Gadher SJ, Kovarova H. (2008) Proteomics of neural stem cells. Expert Rev Proteomics. Apr;5(2):175-86.
Vodicka P, Hlucilova J, Klima J, Prochazka R, Ourednik J, Ourednik V, Motlik J. (2008) The minipig as animal model in biomedical stem cell research. 241-248. Source Book of Models for Biomedical Research, Ed.: P. Michael Conn, Humana Press.
2007
Skalnikova H, Halada P, Vodicka P, Motlik J, Rehulka P, Hørning O, Chmelik J, Jensen ON, and Kovarova H. (2007) A proteomic approach to studying the differentiation of neural stem cells. Proteomics. Jun;7(11):1825-38.
2006
Vodicka P, Skalnikova H, Kovarova H. (2006) The characterization of stem cell proteomes. Curr Opin Mol Ther. Jun;8(3):232-9.
2005
Vodicka P, Smetana K Jr, Dvorankova B, Emerick T, Xu YZ, Ourednik J, Ourednik V, Motlik J. (2005) The miniature pig as an animal model in biomedical research. Ann N Y Acad Sci. May;1049:161-71.
2004
Prochazka R, Vodicka P, Zudova D, Rybar R, Motlik J. (2004) Development of in vivo derived diploid and tetraploid pig embryos in a modified medium NCSU 37. Theriogenology. Jul;62(1-2):155-64.
2000
Pavlok A, Kanka J, Motlik J, Vodicka P. (2000) Culture of bovine oocytes from small antral follicles in meiosis-inhibiting medium with butyrolactone I: RNA synthesis, nucleolar morphology and meiotic kompetence. Anim Reprod Sci. Dec 1;64(1-2):1-11.
Vodicka P, Sevcíková S, Smardová J, Soucek K, Smarda J. (2000) The effects of RAR alpha and RXR alpha proteins on growth, viability, and differentiation of v-MYB-transformed monoblasts. Blood Cells Mol Dis. Aug;26(4):395-406.
1999
Smarda J, Zemanova K, Bryja J, Smardova J, Kozubik A, Hofmanova J, Nemajerova A, Sevcikova S, Kohoutek J, Vodicka P. (1999) Retinoid X receptor suppresses transformation by the v-myb oncogene. J Leukoc Biol. Dec;66(6):1039-48.