Laboratory of Growth Substances
Laboratory of Growth Regulators has been created in 1995 as a joined facility of the Faculty of Science, Palacký University (www.upol.cz) and Institute of Experimental Botany, Academy of Sciences of the Czech Republic (www.ueb.cas.cz).
Research program of the laboratory is aimed primary at small molecules that regulate cell division cycle, proliferation and growth of both plant and animal cells. Namely cytokinins and cytokinin-derived purine inhibitors of cyclin-dependent kinases belongs to the most intensively studied compounds. The representative of the latter, roscovitine (CYC202, seliciclib), already undergoes phase II clinical trials in patients as a novel anticancer drug held by Cyclacel Ltd (for more information see actual Press Release).
Our multidisciplinary research team is composed of experienced plant physiologists, biochemists as well as organic and analytical chemists. Many students are involved in the research during their pregradual and postgraduate studies of botany, analytical and organic chemistry, biochemistry or medicinal biology, respectively.
Laboratory of Growth Regulators guarantees the teaching for biological study programs. Members of the laboratory give lectures from general botany, plant physiology, microbiology, chemistry, molecular biology, including practical courses and seminars.
Several reseach projects are in progress in colaboration with international partners (University of Berlin, Germany; Swedish University of Agricultural Sciences, Sweden; University of Natal Pietermaritzburg, South Africa; Vienna Medical University, Austria).
Workers
head of the laboratorysenior scientist
- Prof. ing. Miroslav Strnad CSc.
scientist
- Jiří Grúz
- Mgr. Ondřej Novák Ph.D.
- Mgr. Lucie Plíhalová Ph.D.
- Mgr. Danuše Tarkowská Ph.D.
- PharmDr. Lubor Urbánek Ph.D.
graduated technical assistant
- Mgr. Ota Blahoušek
- Ivan Petřík
assistant
- Jitka Hansgutová DiS.
technician
- Mgr. Marie Karlická
Research projects
Publications
2013
- JOURNAL OF EXPERIMENTAL BOTANY doi: 10.1093/jxb/ers372 2013 (External fulltext)
2012
- PLANT AND CELL PHYSIOLOGY 53 81-95 2012 (External fulltext)
- PLANT SCIENCE 2012 (External fulltext)
- JOURNAL OF PLANT PHYSIOLOGY 169 696-703 2012 Fulltext: PDF link on intranet only
- JOURNAL OF PLANT GROWTH REGULATION 31 392-405 2012 Fulltext: PDF link on intranet only
- JOURNAL OF EXPERIMENTAL BOTANY doi: 10.1093/jxb/ers197 2012 (External fulltext)
- JOURNAL OF EXPERIMENTAL BOTANY doi:10.1093/jxb/ers356 2012 (External fulltext)
- JOURNAL OF PLANT PHYSIOLOGY 169 567-576 2012 Fulltext: PDF link on intranet only
- PLANT GROWTH REGULATION DOI 10.1007/s10725-012-9707-1 2012 (External fulltext)
- JOURNAL OF PLANT PHYSIOLOGY 169 567-576 2012