Here you can find available positions for Ph.D. as well as undergraduate students at the Institute of Physiology.
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Ph.D. topics
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Master's thesis
Biomaterials and Tissue Engineering
Research topics: Bone, vascular and skin tissue engineering
Candidate’s profile (requirements): Master degree at the Faculty of Science or Medical Faculties of the Charles University
PhD Project1: Use of stem cells in bone tissue engineering
PhD Project2: Engineering of bilayered skin…
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Biomathematics
Candidate’s profile (requirements): MS or Engineer degree from University in EU, Ukraine, Russia, USA, Canada, South Africa, Australia and New Zeeland.
PhD Project 1: Application of modern techniques of fluorescence microscopy (CLSM and FRAP) for determination of mobility of G protein…
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Neurophysiology of Memory
Research topics: The hippocampus, anterior cingulate cortex (ACC) and retrosplenial cortex (RSC) are important for cognitive functions. The present project will aim at elucidating the role of these cortical structures in behavioral flexibility and navigation in a dynamic world. The project…
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Mitochondrial Physiology
We are looking for motivated PGS student for the project studying molecular mechanisms of insulin secretion. We study redox regulated signaling pathways, which participates in insulin secretion from beta cells of pancreatic Langerhans islets and once disrupted, diabetes type II can be developed.…
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Protein Structures
Research topics: Structure and function of the 14-3-3 proteins and their complexes. The 14-3-3 proteins are a family of scaffolding proteins that play an important role in the regulation of signal transduction, apoptosis, cell cycle control, and nutrient-sensing pathways. The 14-3-3 proteins bind…
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Neurohumoral Regulations
Research topics: Molecular mechanisms of interaction between maternal and fetal circadian clocks.
Candidate’s profile (requirements): MSc. degree (or equivalent) in biomedicine-related field, high motivation, deep knowledge of physiology and molecular biology, experience with basic…
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Neurochemistry
Research topics: Physiology and molecular pharmacology of cholinergic muscarinic neurotransmission. Impairment of brain muscarinic neurotransmission in mouse model of Alzheimer´s disease during aging.
Candidate’s profile (requirements): MD or MSc in physiology, cellular biology, biochemistry,…
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Membrane Transport
Research topics: Yeasts are eukaryotic microoroganisms used in industry for the production of a wide range of products, but, due to the similarity of their cellular structure and processes to those of higher eukaryotes, they serve as an important model organism in modern cell biology research. Some…
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Functional Morphology
Research Summary: The main research interest of our department is to study mechanisms of pain and to explore new possibilities of pain treatment, especially in chronic states. Our experimental work is concentrated on the modulation of nociceptive information at the spinal cord…
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Experimental Hypertension
Research topic1: The role of renin-angiotensin (RAS) and endothelin (ET) systems in experimentally induced renal failure
Project background: Chronic kidney disease (CKD) is a world-wide health problem. Both RAS and ET systems play important roles in its development and maintenance. CKD could be…
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Epithelial Physiology
Research topics: Effect of stress on hypothalamus-pituitary-adrenal (HPA) axis, gut inflammation and local biogenesis and metabolism of glucocorticoids
Candidate’s profile (requirements): The candidate must hold a MSc degree in biochemistry/animal physiology or related biomedical fields, medicine…
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Developmental Cardiology
Research topics1: The role of leptin and RNA-demethylase FTO in cardiac tolerance to ischemia-reperfusion injury
Candidate’s profile (requirements): MD or MSc in physiology, cellular biology, biochemistry, molecular biology, or similar. Prior experience in cardiovascular physiology,…
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Cellular Neurophysiology
Research Summary: N-methyl-D-aspartate (NMDA) receptors are a type of ionotropic glutamate receptors mediating fast synaptic transmission and essential for learning and memory. Abnormal function of NMDA receptors underlies many neurological and psychiatric diseases, including schizophrenia…
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Cellular and Molecular Neuroendocrinology
Research topics: neuroendocrinology
Candidate’s profile (requirements): University education in the field of biomedicine, biology, biochemistry or biophysics
PhD Project: Characterization of binding sites for allosteric modulators of purinergic P2X4 receptors, and their role in…
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Bioenergetics
Research topic: Main focus of our department lies on mitochondria, an organelle which accommodates number of key metabolic pathways and governs the life and death of the cell. A lot of our Research goes into the complexes of oxidative phosphorylation apparatus (OXPHOS), regulation of their…
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Adipose Tissue Biology
Research topics1: Obesity, insulin resistance and associated metabolic disorders (Metabolic syndrome). Molecular mechanisms underlying the effects of various lipid forms of omega-3 fatty acids on energy balance, insulin sensitivity and metabolism in obesity.
Candidate’s profile (requirements): MSc…
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Functional Morphology
It is possible to develop a bachelor's, master's and doctoral theses on various topics related to the creation of mechanisms and pain syndromes at our department.
Periferní a centrální mechanizmy bolestivých stavů
Modulace nocicepce na míšní úrovni
Úloha synaptické modulace při nociceptivním…
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Bioenergetics
At the department of Bioenergetics, Institute of Physiology AS CR we offer the following theses’ topics. They can be submitted at the departments of Physiology or Cell biology, Faculty of Science, Charles University.
BSc. projects:
Biogenesis of the…
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