| Education |
| 1999-2004 |
Ph.D. in Molecular Biology and Virology (thesis "HIV-1 Protease Inhibition and Drug Resistance Studied by Structure Analysis and Computational Methods"),
Faculty of Science, Charles University, Prague. |
| 1994-1999 |
M.Sc. in biology, molecular biology, virology, genetics and immunology, Faculty of Science, Charles University, Prague. |
| |
| Courses |
| 1999-2004 |
Ph.D. in Molecular Biology and Virology (thesis "HIV-1 Protease Inhibition and Drug Resistance Studied by Structure Analysis and Computational Methods"),
Faculty of Science, Charles University, Prague. |
|
2001 (2 months) |
Crystallographic refinement, J.R. Mesters, Prof. R. Hilgenfeld, Institut für Molekulare Biotechnologie, Jena, Germany. |
| 2001 (1 month) |
Summer school of quantum chemistry, Dr. P. Nachtigall, Prof. P.Hobza, J. Heyrovský Institute of Physical Chemistry, Prague. |
| 2000 (1 month) |
Course on Combinatorial Chemistry, S. Miertus, International Centre for Genetic Engineering and Biotechnology, Trieste, Italy. |
| 2000 (1 month) |
Course on biomolecular simulations, R. Wade, M. Nilges, European Molecular Biology Laboratories (EMBL), Heidelberg. |
| 1999 (1 month) |
Computational “WHAT IF“ user course, G. Vriend, EMBL, Heidelberg. |
| |
| Experience |
| since 2010 |
Scientist at the group of Prof. Pavel Hobza, Institute of Organic Chemistry and Biochemistry AS CR, Prague. |
| 2007-2009 |
Post-doc with Dr. Lubomír Rulíšek and Dr. Jan Konvalinka, IOCB, Prague. |
| 2006 (11 months) |
Post-doc with Dr. Martin J. Field, Institut de Biologie Structurale, Grenoble. |
| 2004-2005 |
Post-doc with Prof. Pavel Hobza, IOCB, Prague. |
| |
| Research interest |
- drug design
- biomolecular simulations
- borane chemistry
- noncovalent interactions
- reaction mechanisms
- X-ray crystallography
|
