Institute of Physiology, Academy of Sciences of the Czech Republic
Main methodology is provided by mathematical modeling based on the theory of stochastic processes and differential equations, including extensive numerical simulations. Advanced statistical analysis of simulated as well as real experimental data is performed in order to estimate biophysically relevant parameters of the studied models.
Methods of information theory and statistical estimation theory are applied to analyse the neuronal coding efficiency, based on both simulated and experimental data. Of particular interest is the notion of efficient coding hypothesis for insect olfactory sensory neurons, and biophysical modelling of ligand-receptor interaction in pheromone reception.
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