Laboratoř růstových regulátorů
Laboratory of Growth Regulators has been created in 1995 as a joined facility of the Faculty of Science, Palacký University (www.upol.cz) and Institute of Experimental Botany, Academy of Sciences of the Czech Republic (www.ueb.cas.cz).
Research program of the laboratory is aimed primary at small molecules that regulate cell division cycle, proliferation and growth of both plant and animal cells. Namely cytokinins and cytokinin-derived purine inhibitors of cyclin-dependent kinases belongs to the most intensively studied compounds. The representative of the latter, roscovitine (CYC202, seliciclib), already undergoes phase II clinical trials in patients as a novel anticancer drug held by Cyclacel Ltd (for more information see actual Press Release).
Our multidisciplinary research team is composed of experienced plant physiologists, biochemists as well as organic and analytical chemists. Many students are involved in the research during their pregradual and postgraduate studies of botany, analytical and organic chemistry, biochemistry or medicinal biology, respectively.
Laboratory of Growth Regulators guarantees the teaching for biological study programs. Members of the laboratory give lectures from general botany, plant physiology, microbiology, chemistry, molecular biology, including practical courses and seminars.
Several reseach projects are in progress in colaboration with international partners (University of Berlin, Germany; Swedish University of Agricultural Sciences, Sweden; University of Natal Pietermaritzburg, South Africa; Vienna Medical University, Austria).
Pracovníci
vedoucí skupinyvedoucí vědecký pracovník
- Prof. ing. Miroslav Strnad CSc.
vědecký pracovník
- Jiří Grúz
- Mgr. Ondřej Novák Ph.D.
- Mgr. Lucie Plíhalová Ph.D.
- Mgr. Danuše Tarkowská Ph.D.
- PharmDr. Lubor Urbánek Ph.D.
vědecký asistent
- Mgr. Lukáš Spíchal Ph.D.
odborný pracovník
- Mgr. Ota Blahoušek
- Ivan Petřík
sekretářka-asistentka
- Jitka Hansgutová DiS.
laborant
- Mgr. Marie Karlická
Výzkumné projekty
Publikace
2015
- MOLECULAR CELL 57 984-994 2015
- PNAS 112 291-296 2015
- PLANT CELL 27 1955-1967 2015
2014
- PLANTA 240 55-76 2014 (External fulltext)
- PHYTOCHEMISTRY http://dx.doi.org/10.1016/j.phytochem.2014.05.015 2014 (External fulltext)
- JOURNAL OF EXPERIMENTAL BOTANY doi:10.1093/jxb/eru289 2014 (External fulltext)
- PLANT JOURNAL DOI: 10.1111/tpj.12615 2014 (External fulltext)
- PNAS 2014 E3571-E3580 2014
- NATURE COMMUNICATIONS DOI: 10.1038 ncomms 4274 2014
2013
- JOURNAL OF EXPERIMENTAL BOTANY 64 2805-2815 2013 Fulltext: PDF link pouze na intranetu