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12 Jan 13 - 19 Apr 19
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2013

Frey C.R., Andrei G., Votruba I., Cannizzaro C., Han B., Fung W., Hung M., Liu X., Geleziunas R., Fiten P., Opdenakker G., Snoeck R., Cihlar T.:
Mutations in adenosine deaminase-like (ADAL) protein confer resistance to the antiproliferative agents N6-cyclopropyl-PMEDAP and GS-9219.
Anticancer Research 33: 1899-1912, 2013.

Perlíková P., Eberlin L., Ménová P., Raindlová V., Slavětínská L., Tloušťová E., Bahador G., Lee Y.J., Hocek M.:
Synthesis and cytostatic and antiviral activities of 2'-deoxy-2',2'-difluororibo- and 2'-deoxy-2'-fluororibonucleosides derived from 7-(Het)aryl-7-deazaadenines.
ChemMedChem 8: 832-846, 2013.

Tichý M., Pohl R., Tloušťová E., Weber J., Bahador G., Lee Y.J., Hocek M.:
Synthesis and biological activity of benzo-fused 7-deazaadenosine analogues. 5- and 6-substituted 4-amino- or 4-alkylpyrimido[4,5-b]indole ribonucleosides.
Bioorganic & Medicinal Chemistry 21: 5362-5372, 2013.

Perlíková P., Konečný P., Nauš P., Snášel J., Votruba I., Džubák P., Pichová I., Hajdúch M., Hocek M.:
6-Alkyl-, 6-aryl- or 6-hetaryl-7-deazapurine ribonucleosides as inhibitors of human or MTB adenosine kinase and potential antimycobacterial agents.
MedChemComm 4: 1497-1500, 2013.

Plačková P., Rozumová N., Hřebabecký H., Šála M., Nencka R., Elbert T., Dvořáková A., Votruba I., Mertlíková-Kaiserová H.:
9-Norbornyl-6-chloropurine is a novel antileukemic compound interacting with cellular GSH.
Anticancer Research 33: 3163-3168, 2013.