Organic chemistry

The goal of the project is to develop novel non-coded bond formations feasible in living systems. By combining elements of organometallic chemistry, catalysis, and dye chemistry we will create initial benchmarks for an interdisciplinary program targeted towards bio-applications including chemical biology, diagnostics, and therapeutics.

Leading references:

Adriaenssens L., Severa L., Vávra J., Šálová T., Hývl J., Čížková M., Pohl R., Šaman D., Teplý F.:
Bio- and air-tolerant carbon–carbon bond formations via organometallic ruthenium catalysis
Collection of Czechoslovak Chemical Communications 2009, 74, 1023.

Streu C., Meggers E.:
Ruthenium-Induced Allylcarbamate Cleavage in Living Cells
Angew. Chem. Int. Ed. 2006, 45, 5645.