The research group mainly focuses on 3D image acquisition and image processing of microscopic and macroscopic biological features, for example, cell ultrastructures, cells, tissues, organs or entire organisms. In addition, new evaluation and computer methods are designed upon specific requirements.

The main areas of the research are:

• 3D image analysis, stereology, spatial statistics, 3D reconstruction
• First- and second-order stereological methods: study of variance of the methods, new methods and software development, consulting and tutorials
• 3D microscopy of biological specimens:

1. confocal and two-photon excitation microscopy: data processing and analysis, application of modern fluorescence approaches and recent two-photon excitation trends, calibration services, deconvolution, service and maintenance of Leica confocal microscopes including pulse near-infrared laser, consulting and tutorials
2. optical projection tomography, fluorescence and transmitted light microscopy of specimens at the submacroscopic level, optical clearing of specimens

The instruments are adopted for a wide range of projects, for example, bird brain anatomy, conduction system of the heart, capillary system of the human placenta, rat muscles and brain, extracellular matrix proteins – collagen and elastin, architecture of the spruce needle and its cells, for instance, structure of the nucleus and of the endoplasmic reticulum.

Laboratory of Biochemistry of Membrane Receptors