2004
Turek P., Kotora M., Tišlerová I., Hocek M., Votruba I., Císařová I.:
Cocyclotrimerization of 6-alkynylpurines with diynes as a novel approach to biologically active 6-arylpurines.
Journal of Organic Chemistry 26 (69): 9224-9233, 2004.
Fernandez-Botello A., Holý A., Moreno V., Sigel H.:
Intramolecular stacking interactions in ternary copper(II) complexes formed by a heteroaromatic amine and 9-[2-(2-phosphonoethoxy)ethyl]adenine, a relative of the antiviral nucleotide analogue 9-[2-(phosphonomethoxy)ethyl]adenine.
Journal of Inorganic Biochemistry 12 (98): 2114-2124, 2004.
Gomez-Coca R.B., Kapinos L.E., Holý A., Vilaplana R.A., Gonzalez-Vilchez F., Sigel H.:
Quantification of isomeric equilibria formed by metal ion complexes of 8-[2-(phosphonomethoxy)ethyl]-8-azaadenine (8,8aPMEA) and 9-[2-(phosphonomethoxy)ethyl]-8-azaadenine (9,8aPMEA). Derivatives of the antiviral nucleotide analogue 9-[2-(phosphonomethoxy) ethyl]adenine (PMEA).
Journal of Biological Inorganic Chemistry 8 (9): 961-972, 2004.
Zídek Z., Kmoničková E., Holý A.:
Involvement of adenosine A1 receptors in upregulation of nitric oxide by acyclic nucleotide analogues.
European Journal of Pharmacology 1-3 (501): 79-86, 2004.
Krečmerová M., Masojídková M., Holý A.:
Synthesis of N9- and N7-[2-hydroxy-3- (phosphonomethoxy)-propyl] derivatives of N6-substituted adenines, 2,6-diaminopurines and related compounds.
Collection of Czechoslovak Chemical Communications 10 (69): 1889-1913, 2004.
Bzowska A., Koellner G., Wielgus-Kutrowska B., Stroh A., Raszewski G., Holý A., Steiner T., Frank J.:
Crystal structure of calf spleen purine nucleoside phosphorylase with two full trimers in the asymmetric unit: Important implications for the mechanism of catalysis.
Journal of Molecular Biology 3 (342): 1015-1032, 2004.
Otmar M., Masojídková M., Votruba I., Holý A.:
Synthesis and antiproliferative activity of 2,6-diamino-9-benzyl-9- deazapurine and related compounds.
Bioorganic and Medicinal Chemistry 12 (12): 3187-3195, 2004.
Hocková D., Holý A., Masojídková M., Andrei G., Snoeck R., De Clercq E., Balzarini J.:
Synthesis and antiviral activity of 2,4-diamino-5-cyano-6-[2- (phosphonomethoxy)ethoxy]pyrimidine and related compounds.
Bioorganic and Medicinal Chemistry 12 (12): 3197-3202, 2004.
Hocková D., Holý A., Masojídková M., Votruba I.:
An efficient synthesis of cytostatic mono and bis-alkynylpyrimidine derivatives by the Sonogashira cross-coupling reactions of 2,4-diamino-6- iodopyrimidine and 2-amino-4,6-dichloropyrimidine.
Tetrahedron 23 (60): 4983-4987, 2004.
Hocek M., Štěpnička P., Ludvik J., Císařová I., Votruba I., Reha D., Hobza P.:
Ferrocene-Modified Purines as Potential Electrochemical Markers: Synthesis, Crystal Structures, Electrochemistry and Cytostatic Activity of (Ferrocenylethynyl)- and (Ferrocenylethyl)purines.
Chemistry - A European Journal 8 (10): 2058-2066, 2004.
Šála M., Hřebabecký H., Masojídková M., Holý A.:
Synthesis of racemic 2-hydroxy-4- and 2-hydroxy-5-(hydroxymethyl) cyclohexane pyrimidine C-Nucleoside analogues.
Collection of Czechoslovak Chemical Communications 4 (69): 918-932, 2004.
Hřebabecký H., Masojídková M., Holý A.:
Synthesis of purine nucleoside analogues derived from carbocyclic 5-C-(hydroxymethyl)hexopyranoses.
Collection of Czechoslovak Chemical Communications 2 (69): 435-452, 2004.
Balzarini J., Pannecouque C., Naesens L., Andrei G., Snoeck R., De Clercq E., Hocková D., Holý A.:
6-[2-Phosphonomethoxy)alkoxy]-2,4-diaminopyrimidines: A new class of acyclic pyrimidine nucleoside phosphonates with antiviral activity.
Nucleosides, Nucleotides and Nucleic Acids 8-9 (23): 1321-1327, 2004.
Birkus G., Rejman D., Otmar M., Votruba I., Rosenberg I., Holý A.:
The substrate activity of (S)-9-[3-hydroxy-(2-phosphonomethoxy)propyl]adenine diphosphate toward DNA polymerases α, β and ε.
Antiviral Chemistry and Chemotherapy 1 (15): 23-33, 2004.