Scientific Program

One-day symposium dedicated to 80^th anniversary of Prof. Antonin Holy

Opening 8:50 - 9:00

Invitation:  Zdeněk Hostomský, IOCB AS CR director
Opening:  Zdeněk Havlas IOCB AS CR

Session 1 (09:00 - 10:50)

Chairman : Michal Hocek

1.1 09:00 - 09:30 Tomáš Cihlář (Vice President, Virology at Gilead Sciences)
A. Holy - tribute
1.2 09:30 - 10:30 Dennis C. Liotta (Emory, USA)
Drug Development in Academia
1.3 10:30 - 10:50 A.Michael Downey (IOCB AS CR)
Protection-free glycosylations for synthesis of nucleosides

10:50 - 11:10 Coffee Break

Session 2 (11:10 - 12:50)

Chairman : Michal Hocek

2.1 11:10 - 11:50 Chung K. Chu (University of Georgia)
FMCA as a Novel Anti-HBV Agent
2.2 11:50 - 12:10 Jan Frydrych (IOCB AS CR)
Novel acyclic nucleoside phosphonates as potential inhibitors of bacterial adenylate cyclases
2.3 12:10 - 12:50 Victor E. Marquez (Chemical Biology Laboratory, National Cancer Institute, NIH)
Following the Steps of a Leader (Tony Holy,  1936 - 2012): The Story of N-Methanocarbathymidine from Basic Concepts to an IND

12:50 - 14:20 Lunch

Session 3 (14:20 - 16:00)

Chairman : Zdeněk Havlas

3.1 14:20 - 15:00 Frank Seela (Center for Nanotechnology, University of Munster, DE)
Modified DNA as Target for Click Reactions and Silver-Mediated Base Pairs
3.2 15:00 - 15:20 Milan Dejmek (IOCB AS CR)
Novel methodology for construction of purine nucleobases and application in the synthesis of locked nucleosides analogues
3.3 15:20 - 16:00 Piet Herdewijn (Rega institute, KU Leuven)
In vivo transliteration of artificial nucleic acids

16:00 - 16:10 Zdeněk Havlas - Concluding remarks