2009
Hocková D., Holý A., Masojídková M., Keough D.T., Jersey J.d., Guddat L.W.:
Synthesis of branched 9-[2-(2-phosphonoethoxy)ethyl]purines as a new class of acyclic nucleoside phosphonates which inhibit Plasmodium
falciparum hypoxanthine-guanine-xanthine phosphoribosyltransferase.
Bioorganic and Medicinal Chemistry 17: 6218-6232, 2009.
Dračinský M., Holý A., Jansa P., Kovačková S., Budešínský M.:
Isotopic exchange of hydrogen at C-5 in pyrimidine derivatives: tautomers with an sp3-hybridised C-5 carbon atom.
European Journal of Organic Chemistry 24: 4117-4122, 2009.
Doláková P., Dračínský M., Fanfrlík, J., Holý, A.:
Synthesis of analogues of acyclic nucleoside diphosphates containing a (phosphonomethyl)phosphanyl moiety and studies of their phosphorylation.
European Journal of Organic Chemistry 7: 1082-1092, 2009.
Doláková P., Dračínský M., Masojídková M., Šolínová V., Kašička V., Holý, A.:
Acyclic nucleoside bisphosphonates: Synthesis and properties of chiral 2-amino-4,6-bis[(phosphonomethoxy)alkoxy]pyrimidines.
European Journal of Medicinal Chemistry 44: 2408-2424, 2009.
Fernández-Botello A., Holý A., Moreno V., Operschall B.P., Sigel H.:
Intramolecular π-π stacking interactions in aqueous solution in mixed-ligand copper(II) complexes formed by heteroaromatic amines and the nucleotide analogue 9-[2-(phosphonomethoxy)ethyl]-2-aminopurine (PME2AP), an isomer of the antivirally active 9-[2-(phosphonomethoxy)ethyl]adenine (PMEA).
Inorganica Chimica Acta 362: 799-810, 2009.
Šolínová V., Kašička V., Sázelová P., Holý A.:
Chiral analysis of anti-acquired immunodeficiency syndrome drug, 9-(R)-[2-(phosphonomethoxy)propyl]adenine (tenofovir), and related antiviral acyclic nucleoside phosphonates by CE using b-CD as chiral selector.
Electrophoresis 30: 2245-2254 , 2009.
Keough D.T., Hocková D., Holý A., Naesens L.M.J., Skinner-Adams T.S., De Jersey J., Guddat L.W.:
Inhibition of hypoxanthine-guanine phosphoribosyltransferase by acyclic nucleoside phosphonates: A new class of antimalarial therapeutic.
Journal of Medicinal Chemistry 14: 4391-4399, 2009.
Konvalinka J., Illnerová H., Hobza P., Hoøejší V., Holý A., Jungwirth P., Paèes V.:
Czech bibliometric system fosters mediocre research.
Nature 460: 1079, 2009.
Šála M., Hřebabecký H., Dračínský M., Masojídková M., De Palma A.M., Neyts J., Holý A.:
Norbornane as the novel pseudoglycone moiety in nucleosides.
Tetrahedron 65: 9291-9299, 2009.
Krečmerová, M., Holý, A.:
Syntheses of antivirals from the family of acyclic nucleoside phosphonates and their prodrugs.
PharmaChem: 6-9, 2009.
Pomeisl K., Holý A., Pohl R., Horská K.:
Use of Pd-catalyzed Suzuki-Miyaura coupling reaction in the rapid synthesis of 5-aryl-6-(phosphonomethoxy)uracils and evaluation of their inhibitory effect towards human thymidine phosphorylase.
Tetrahedron 65: 8486-8492, 2009.
Otová B., Hrdý J., Votruba I., Holý A.:
Modulation of angiogenic genes expression by acyclic nucleoside phosphonates PMEDAP and PMEG.
Anticancer Res. 29: 1295-1302, 2009.
Hřebabecký H., Dračínský M., De Palma A.M., Neyts J., Holý A.:
Synthesis of novel carbocyclic nucleoside analogues derived from 7-oxabicyclo[2.2.1]heptane-2-methanol.
Collect. Czech. Chem. Commun. 74: 487-502, 2009.
Hřebabecký H., Dračínský M., De Palma A.M., Neyts J., Holý A.:
Synthesis of novel racemic carbocyclic nucleoside analogues derived from 4,8-dioxatricyclo[4.2.1.03,7]nonane-9-methanol and 4-oxatricyclo[4.3.1.03,7]decane-10-methanol, compounds with activity against Coxsackie viruses.
Collect. Czech. Chem. Commun. 74: 469-485, 2009.