2008
Gratz-Šašková K., Kožíšek M., Lepšík M., Brynda J., Řezáčová P., Václavíková J., Kagan R.M., Machala, L., Konvalinka, J.:
Molecular Mechanism of Reduced Susceptibility of HIV Protease to the Protease Inhibitor Lopinavir Conferred by the I47A Mutation.
Protein Science 17: 1555-1564, 2008.
Krejčiříková V., Fábry M., Marková V., Malý P., Řezáčová P., Brynda J.:
Crystallization and preliminary X-ray diffraction analysis of mouse galectin-4 N-terminal carbohydrate recognition domain in complex with lactose.
Acta Crystallographica F 64: 665-667, 2008.
Kožíšek M., Cígler P., Lepšík M., Fanfrlík J., Řezáčová P., Brynda J., Pokorná J., Plešek J., Grüner B., Grantz-Šašková K., Václavíková J., Kraeusslich H.-G., Král V., Konvalinka J.:
Inorganic polyhedral metallacarborane scaffolds - a new approach to overcoming resistance to HIV protease inhibitors.
Journal of Medicinal Chemistry 51: 4839-4843, 2008.
Řezáčová P., Kožíšek M., Moy S.F., Sieglová I., Joachimiak A., Machius M., Otwinowski Z.:
Crystal structures of the effector-binding domain of repressor CggR from Bacillus subtilis reveal ligand-induced structural changes upon binding of several glycolytic intermediates.
Molecular Microbiology 69: 895-910, 2008.
Kožíšek M., Šašková K., Řezáčová P., Brynda J., van Maarseveen N.M., De Jong D., Boucher Ch., Kagan R., Nijhuis M., Konvalinka J.:
Ninety Nine is Not Enough: Molecular Characterisation of Drug-Resistant HIV-Protease Mutants with Insertions in the Flap Region Yielding Resistance to Protease Inhibitors.
Journal of Virology 82: 5869-5878, 2008.
Bartoňová V., Král V., Sieglová I., Brynda J., Fábry M., Hořejší M., Kožíšek M., Grantz Šašková K., Konvalinka J., Sedláček J., Řezáčová P.:
Potent inhibition of drug-resistant HIV protease variants by monoclonal antibodies.
Antiviral Research 78: 275-277, 2008.
Král V., Mader P., Collard R., Fábry M., Hořejší M., Řezáčová P., Kožíšek M., Závada J., Sedláček J., Rulíšek L., Brynda J.:
Stabilization of antibody structure upon association to a human carbonic anhydrase IX epitope studied by X-ray crystallography, microcalorimetry, and molecular dynamics simulations.
Proteins: Structure, Function, and Bioinformatics 71: 1275-1287, 2008.
Řezáčová P., Borek D., Moy S., Joachimiak A., Otwinowski Z.:
Structure and function of small Toprim domain protein from Bacillus stearothermophyllus.
Proteins: Structure, Function, and Bioinformatics 70: 311-319, 2008.
Štefko M., Pohl R., Klepetářová B., Hocek M.:
A Modular Methodology for the Synthesis of 4- and 3-Substituted Benzene and Aniline C-Ribonucleosides.
European Journal of Organic Chemistry 1689-1704, 2008.
Bárta J., Pohl R., Klepetářová B., Ernsting N. P., Hocek M.:
Modular Synthesis of 5-Substituted Thiophen-2-yl C-2'-Deoxyribonucleosides.
Journal of Organic Chemistry 73: 3798-3806, 2008.
Turek P., Hocek M., Pohl R., Klepetářová B., Kotora M.:
Cobalt-Induced Synthesis of 6-(Pyridin-2-yl)purines by Microwave-Enhanced [2+2+2] Cyclotrimerization.
European Journal of Organic Chemistry 3335-3343, 2008.
Kuchař M., Pohl R., Klepetářová B., Votruba I., Hocek M.:
Synthesis of substituted 6-cyclopropylpurine bases and nucleosides by cross-coupling reactions or cyclopropanations.
Organic & Biomolecular Chemistry 6: 2377-2387, 2008.
Kuchař M., Pohl R., Klepetářová B., Hocek M.:
Synthesis of diverse 6-(1,2-disubstituted ethyl)purine bases and nucleosides via 6-(oxiran-2-yl)purines.
Tetrahedron 64: 10355-10364, 2008.
Čerňa I., Pohl R., Klepetářová B., Hocek M.::
Synthesis of 6,8,9-Tri- and 2,6,8,9-Tetrasubstituted Purines by a Combination of the Suzuki Cross-coupling, N-Arylation, and Direct C-H Arylation Reactions.
Journal of Organic Chemistry 73: 9048-9054, 2008.