Mgr. Michal Tichý, Ph.D.
phone: +420 220183343
Born 10. 10. 1984 in Brandýs nad Labem (Czech Republic).
Scientific CV:
2004-2007 undergraduate study, Charles University in Prague - Faculty of Science, Bc. S. degree - specialization clinical and toxicological analysis (supervisor RNDr. Jan Šarek, Ph.D.)
2007-2009 undergraduate study, Charles University in Prague - Faculty of Science, M. S. degree - specialization organic chemistry (supervisor RNDr. Jan Šarek, Ph.D.)
2009-2015 PhD study, Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic (supervisor Dr. M. Hocek)
since 2015 Postdoctoral stay ETH Zürich
Awards:
2009 Zentiva award for the best diploma thesis (2nd position)
List of publications:
| 4. | Bosáková, A.; Perlíková, P.; Tichý, M.; Pohl, R.; Hocek, M.: "6-Aryl-4-amino-pyrimido[4,5-b]indole 2'-deoxyribonucleoside triphosphates (benzo-fused 7-deaza-dATP analogues): Synthesis, fluorescent properties, enzymatic incorporation into DNA and DNA-protein binding study" Bioorg. Med. Chem. 2016, 24, 4528 - 4535. |
| 3. | Tichý, M.; Pohl, R.; Tloušťová, E.; Weber, J.; Bahador, G.; Lee, Y.-J.; Hocek, M.: "Synthesis and biological activity of benzo-fused 7-deazaadenosine analogues. 5- and 6-substituted 4-amino- or 4-alkylpyrimido [4,5-b]indole ribonucleosides" Bioorg. Med. Chem. 2013, 21, 5362–5372. |
| 2. | Tichý, M.; Pohl, R.; Xu, H. Y.; Chen, Y.-L.; Yokokawa, F.; Shi, P.-Y.; Hocek, M.: "Synthesis and antiviral activity of 4,6-disubstituted pyrimido[4,5-b]indole ribonucleosides" Bioorg. Med. Chem. 2012, 20, 6123–6133. |
| 1. | Krasulová, J.; Hanus, R.; Kutalová, K.; Šobotník, J.; Sillam-Dusse`s, D.; Tichý, M.; Valterová, I.: "Chemistry and Anatomy of the Frontal Gland in Soldiers of the Sand Termite Psammotermes hybostoma" J. Chem. Ecol. 2012, 38, 557–565. |
