News

Den otevřených dveří 4. 11. 2016

International Conference on Cell Biology and Radiobiology

The International Conference on Cell Biology and Radiobiology is being organized by the Institute of Biophysics, v.v.i., in Brno in 8th – 10th September 2016.

New publications

Azidophenyl as a click-transformable redox label of DNA suitable for electrochemical detection of DNA-protein interactions

Balintova, J., Spacek, J., Pohl, R., Brazdova, M., Havran, L., Fojta, M., Hocek, M.

How to interpret Methylation Sensitive Amplified Polymorphism (MSAP) profiles?

Fulnecek, J., Kovarik, A.

Differential effects of indirubin and 2,3,7,8-tetrachlorodibenzo-p-dioxin on the aryl hydrocarbon receptor (AhR) signalling in liver progenitor cells

Prochazkova, J., Kozubik, A., Machala, M., Vondracek, J.

Unique DNA Binding Mode of Antitumor Trinuclear Tridentate Platinum(II) Compound

Olivova, R., Kasparkova, J., Vrana, O., Vojtiskova, M., Suchankova, T., Novakova, O., He, WJ., Guo, ZJ., Brabec, V.

Reactive Conformation of the Active Site in the Hairpin Ribozyme Achieved by Molecular Dynamics Simulations with epsilon/zeta Force Field Reparametrizations

Mlynsky, V., Kuhrova, P., Zgarbova, M., Jurecka, P., Walter, NG., Otyepka, M., Sponer, J., Banas, P.
Further publications

Selected results

Unfolding/denaturation and aggregation of proteins viewed by electrochemical methods

Pioneering work of the group headed by prof. E. Paleček in the field of electrochemical analysis of proteins based on their electrocatalytic activity giving rise to “peak H”.

Plant Genetics in Brno

Sequencing of telomeres in onion

Twenty years old challenge - unknown telomeric sequence in onion and garlic from genus Allium, plants with large genomes and relatively low chromosomal numbers was solved. New ″onion″ motif, (CTCGGTTATGGG)n, is the longest and the most divergent known plant telomere variant so far.

Strukturní vlastnosti DNA - nositelky genetické informace

Jedním z renomovaných světových pracovišť, systematicky a dlouhodobě se zabývajících studiem strukturních vlastností nukleových kyselin je laboratoř Prof. RNDr. Michaely Vorlíčkové, DrSc. 

Detecting DNA damage and monitoring of enzymatic DNA processing by electrochemical methods

Electrochemical approaches have been applied to detect specific nucleobase lesions and to design fast techniques for the monitoring of DNA-processing enzymes activity.

Further results