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Ion Channels
Research in the Weiss lab is directed toward understanding the molecular and cellular mechanisms underlying human diseases caused by dysfunction of ion channels,
and more particularly calcium channels. Calcium is Mother Nature’s "ion-of-choice" for orchestrating fundamental cellular functions, as it contribute to neuronal
excitability, muscle contraction, gene transcription, and a plethora of other key processes contributing to the normal physiology of the body. Calcium channels,
which act as gated pathways for the movement of Ca2+ across the cell membranes, play a central part in the initiation of the Ca2+ signals,
and defects in Ca2+ channel function have dramatic consequences resulting in sever human diseases, so-called channelopathies.
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