2015

Buchta M., Rybáček J., Jančařík A., Kudale A. A., Buděšínský M., Vacek Chocholoušová J., Vacek J., Bednárová L., Císařová I., Bodwell G. J., Starý I., Stará I. G.:
Chimerical Pyrene-Based [7]Helicenes as Twisted Polycondensed Aromatics.
Chemistry - A European Journal. 21(24): 8910-8917, 2015.

Fabre B., Pícha J., Vaněk V., Buděšínský M., Jiráček J.:
A CuAAC-Hydrazone-CuAAC Trifunctional Scaffold for the Solid-Phase Synthesis of Trimodal Compounds: Possibilities and Limitations.
Molecules. 20(10): 19310-19329, 2015.

García Y. R., Zelenka J., Pabon Y. V., Iyer A., Buděšínský M., Kraus T., Smith C. I. E., Madder A.:
Cyclodextrin-peptide conjugates for sequence specific DNA binding.
Organic & Biomolecular Chemistry. 13(18): 5273-5278, 2015.

Harmatha J., Vokáč K., Buděšínský M., Zídek Z., Kmoníčková E.:
Immunobiological properties of sesquiterpene lactones obtained by chemically transformed structural modifications of trilobolide.
Fitoterapia. 107: 90-99, 2015.

Kudová E., Chodounská H., Slavíková B., Buděšínský M. , Nekardová M., Vyklický V., Krausová B., Švehla P., Vyklický L.:
A New Class of Potent N-Methyl-D-Aspartate Receptor Inhibitors: Sulfated Neuroactive Steroids with Lipophilic D-Ring Modifications.
Journal of Medicinal Chemistry. 58(15): 5950-5966, 2015.

Pachl P., Šimák O., Řezáčová P., Fábry M., Buděšínský M., Rosenberg I. Brynda J.:
Structure-based design of a bisphosphonate 5 '(3 ')-deoxyribonucleotidase inhibitor.
MedChemComm. 6(9): 1635-1638, 2015.

Petrová M., Páv O., Buděšínský M., Zborníková E., Novák P., Rosenbergová Š., Pačes O., Liboska R., Dvořáková I., Šimák O., Rosenberg I.:
Straightforward Synthesis of Purine 4 '-Alkoxy-2 '-deoxynucleosides: First Report of Mixed Purine-Pyrimidine 4 '-Alkoxyoligodeoxynucleotides as New RNA Mimics.
Organic Letters. 17(14): 3426-3429, 2015.

Tomanová P., Šturala J., Buděšínský M., Cibulka R.:
A Click Chemistry Approach towards Flavin-Cyclodextrin Conjugates-Bioinspired Sulfoxidation Catalysts.
Molecules. 20(11): 19837-19848, 2015.

Tomanová P., Rimpelová S., Jurášek M., Buděšínský M., Vejvodová L., Ruml T., Kmoníčková E., Drašar, P. B.:
Effects of Quantum Nuclear Delocalisation on NMR Parameters from Path Integral Molecular Dynamics.
Steroids. 97: 8-12, 2015.

Vaněk V., Pícha J., Fabre B., Buděšínský M., Lepšík M., Jiráček J.:
The Development of a Versatile Trifunctional Scaffold for Biological Applications.
European Journal of Organic Chemistry. 2015(17): 3689-3701, 2015.

Volkov S., Kumprecht L., Buděšínský M., Lepšík M., Dušek M., Kraus T.:
A gamma-cyclodextrin duplex connected with two disulfide bonds: synthesis, structure and inclusion complexes.
Organic & Biomolecular Chemistry. 13(10): 2980-2985, 2015.

Andrushchenko V., Benda L., Páv O., Dračínský M., Bouř P.:
Vibrational Properties of the Phosphate Group Investigated by Molecular Dynamics and Density Functional Theory.
Journal of Physical Chemistry B. 119(33): 10682-10692, 2015.

Česnek M., Jansa P., Šmídková M., Mertlíková-Kaiserová H., Dračínský M., Brust T. F., Pávek P., Trejtnar F., Watts V. J., Janeba Z.:
Bisamidate Prodrugs of 2-Substituted 9-[2-(Phosphonomethoxy)ethyl]adenine (PMEA, adefovir) as Selective Inhibitors of Adenylate Cyclase Toxin from Bordetella pertussis.
ChemMedChem. 10(8): 1351-1364, 2015.

Dejmek M, Šála M., Hřebabecký H., Dračínský M., Procházková E., Chalupská D., Klíma M., Plačková P., Hájek M., Andrei G., Naesens L., Leyssen P., Neyts J., Balzarini J., Bouřa E., Nencka R.:
Norbornane-based nucleoside and nucleotide analogues locked in North conformation.
Bioorganic & Medicinal Chemistry. 23(1): 184-191, 2015.

Dračínský M.Pohl R.:
Determination of the Nucleic Acid Adducts Structure at the Nucleoside/Nucleotide Level by NMR Spectroscopy.
Chemical Research in Toxicology. 28(2): 155-165, 2015.

Dračínský M., Čechová L., Hodgkinson P., Procházková E., Janeba Z.:
Resonance-assisted stabilisation of hydrogen bonds probed by NMR spectroscopy and path integral molecular dynamics.
Chemical Communications. 51(73): 13986-13989, 2015.

Dračínský M., Hodgkinson P.:
Solid-state NMR studies of nucleic acid components.
RSC Advances. 5(16): 12300-12310, 2015.

Jansa P., Holý A., Dračínský M., Kolman V., Janeba Z., Kmoníčková E., Zídek Z.:
Synthesis and structure-activity relationship studies of polysubstituted pyrimidines as inhibitors of immune-activated nitric oxide production.
Medicinal Chemistry Research. 24(5): 2154-2166, 2015.

Kaiser M. M., Hocková D., Wang T. H., Dračínský M., Poštová Slavětínská L., Procházková E., Edstein M. D., Chavchich M., Keough D. T., Guddat L. W., Janeba Z.:
Synthesis and Evaluation of Novel Acyclic Nucleoside Phosphonates as Inhibitors of Plasmodium falciparum and Human 6-Oxopurine Phosphoribosyltransferases.
ChemMedChem. 10(10): 1707-1723, 2015.

Kessler J., Dračínský M., Bouř P.:
Determination of Absolute Configuration in Chiral Solvents with Nuclear Magnetic Resonance. A Combined Molecular Dynamics/Quantum Chemical Study.
Journal of Physical Chemistry A. 119(21): 5260-5268, 2015.

Paluch P., Pawlak T., Jeziorna A., Trébosc J., Hou G., Vega A. J., Amoureux J. P., Dračínský M., Polenova T., Potrzebowski M. J.:
Analysis of local molecular motions of aromatic sidechains in proteins by 2D and 3D fast MAS NMR spectroscopy and quantum mechanical calculations.
Physical Chemistry Chemical Physics. 17(43): 28789-28801, 2015.

Šála M., Dejmek M., Procházková E., Hřebabecký H., Rybáček J., Dračínský M., Novák P., Rosenbergová Š., Rosenberg I., Nencka R.:
A New Analogue of Locked Cyclohexane Nucleic Acids.
Synthesis. 47(17): 2654-2662, 2015.

Šála M., Dejmek M., Procházková E., Hřebabecký H., Rybáček J., Dračínský M., Novák P., Rosenbergová Š., Fukal J., Sychrovský V., Rosenberg I., Nencka R.:
Synthesis of locked cyclohexene and cyclohexane nucleic acids (LCeNA and LCNA) with modified adenosine units.
Organic & Biomolecular Chemistry. 13(9): 2703-2715, 2015.

Amatov T., Pohl R., Císařová I., Jahn U.:
Synthesis of Bridged Diketopiperazines by Using the Persistent Radical Effect and a Formal Synthesis of Bicyclomycin.
Angewandte Chemie - International Edition. 54(41): 12153-12157, 2015.

Balintová J., Špaček J., Pohl R., Brázdová M., Havran L., Fojta M., Hocek M.:
Azidophenyl as a click-transformable redox label of DNA suitable for electrochemical detection of DNA-protein interactions.
Chemical Science. 6(1): 575-587, 2015.

Daďová J., Vrábel M., Adámik M., Brázdová M., Pohl R., Fojta M., Hocek M.:
Azidopropylvinylsulfonamide as a New Bifunctional Click Reagent for Bioorthogonal Conjugations: Application for DNA-Protein Cross-Linking.
Chemistry - A European Journal. 21(45): 16091-16102, 2015.

Downey A. M., Richter C., Pohl R., Mahrwald R., Hocek M.:
Direct One-Pot Synthesis of Nucleosides from Unprotected or 5-O-Monoprotected D-Ribose.
Organic Letters. 17(18): 4604-4607, 2015.

Dziuba D., ,b>Pohl R., Hocek M.:
Polymerase synthesis of DNA labelled with benzylidene cyanoacetamide-based fluorescent molecular rotors: fluorescent light-up probes for DNA-binding proteins.
Chemical Communications. 51(23): 4880-4882, 2015.

Hocková D., Rosenbergová Š., Ménová P., Páv O., Pohl R., Novák P., Rosenberg I.:
N-Branched acyclic nucleoside phosphonates as monomers for the synthesis of modified oligonucleotides.
Organic & Biomolecular Chemistry. 13(15): 4449-4458, 2015.

Holan M., Pohl R., Císařová I., Klepetářová B., Jones P. G., Jahn U.:
Highly Functionalized Cyclopentane Derivatives by Tandem Michael Addition/Radical Cyclization/Oxygenation Reactions.
Chemistry - A European Journal. 21(27): 9877-9888, 2015.

Jahn E., Smrček J., Pohl R., Císařová I., Jones P. G., Jahn U.:
Facile and Highly Diastereoselective Synthesis of syn- and cis-1,2-Diol Derivatives from Protected alpha-Hydroxy Ketones.
European Journal of Organic Chemistry. 2015(35): 7785-7798, 20145

Kyjaková P., Dolejšová K., Krasulová J., Bednárová L., Hadravová R., Pohl R., Hanus R.:
The evolution of symmetrical snapping in termite soldiers need not lead to reduced chemical defence.
Biological Journal of the Linnean Society. 115(4): 818-825, 2015.

Oroszová B., Choutka J., Pohl R., Parkan K.:
Modular Stereoselective Synthesis of (1 -> 2)-C-Glycosides based on the sp(2)-sp(3) Suzuki-Miyaura Reaction.
Chemistry - A European Journal. 21(19): 7043-7047, 2015.

Panova N., Zborníková E., Šimák O., Pohl R., Kolář M., Bogdanová K., Večeřová R., Seydlová G., Fišer R., Hadravová R., Šanderová H., Vítovská D., Šiková M., Látal T., Lovecká P., Barvík I., Krásný L., Rejman D.:
Insights into the Mechanism of Action of Bactericidal Lipophosphonoxins.
PLoS ONE. 10(12): e0145918/1-e0145918/28, 2015.

Pohl R., Poštová Slavětínská L., Eng W. S., Keough D. T., Guddat L. W., Rejman D.:
Synthesis, conformational studies, and biological properties of phosphonomethoxyethyl derivatives of nucleobases with a locked conformation via a pyrrolidine ring.
Organic & Biomolecular Chemistry. 13(16): 4693-4705, 2015.

Reyes Gutierrez P. E., Jirásek M., Severa L., Novotná P., Koval D., Sázelová P., Vávra J., Meyer A., Císařová I., Šaman D., Pohl R., Štěpánek P., Slavíček P., Coe B. J., Hájek M., Kašička V., Urbanová M., Teplý F.:
Functional helquats: helical cationic dyes with marked, switchable chiroptical properties in the visible region.
Chemical Communications. 51(9): 1583-1586, 2015.

Synytsya A., Choi D. J., Pohl R., Na Y. S., Capek P., Lattová E., Taubner T., Choi J. W., Lee C. W., Park J. K., Kim W. J., Kim S. M., Lee J., Park Y. I.:
Structural Features and Anti-coagulant Activity of the Sulphated Polysaccharide SPS-CF from a Green Alga Capsosiphon fulvescens.
Marine Biotechnology. 17(6): 718-735, 2015.

Klečka M., Poštová Slavětínská L., Hocek M.:
Modification of Pyrrolo[2,3-d]pyrimidines by C-H Borylation Followed by Cross-Coupling or Other Transformations: Synthesis of 6,8-Disubstituted 7-Deazapurine Bases.
European Journal of Organic Chemistry. 2015(36): 7943-7961, 2015.

Klečka M., Poštová Slavětínská L., Tloušťová E., Džubák P., Hajdúch M., Hocek M.:
Synthesis and cytostatic activity of 7-arylsulfanyl-7-deazapurine bases and ribonucleosides.
MedChemComm. 6(4): 576-580, 2015.

Mačková M., Boháčová S., Perlíková P., Poštová Slavětínská L., Hocek M.:
Polymerase Synthesis and Restriction Enzyme Cleavage of DNA Containing 7-Substituted 7-Deazaguanine Nucleobases.
Chembiochem. 16(15): 2225-2236, 2015.

Malnuit V., Poštová Slavětínská L., Nauš P., Džubák P., Hajdúch M., Stolaříková J., Snášel J., Pichová I., Hocek M.:
2-Substituted 6-(Het)aryl-7-deazapurine Ribonucleosides: Synthesis, Inhibition of Adenosine Kinases, and Antimycobacterial Activity.
ChemMedChem. 10(6): 1079-1093, 2015.

Nauš P., Caletková O., Perlíková P., Poštová Slavětínská L., Tloušťová E., Hodek J., Weber J., Džubák P., Hajdúch M., Hocek M.:
Synthesis and biological profiling of 6-or 7-(het)aryl-7-deazapurine 4 '-C-methylribonucleosides.
Bioorganic & Medicinal Chemistry. 23(23): 7422-7438, 2015.

Sabat N., Poštová Slavětínská L., Hocek M.:
Ir-catalyzed C-H silylations of phenyldeazapurines.
Tetrahedron Letters. 56(49): 6860-6862, 2015.

Tokarenko A., Poštová Slavětínská L., Klepetářová B., Hocek M.:
Synthesis of Benzene and Pyridine 2-C-Methyl-C-ribonucleosides and -nucleotides.
European Journal of Organic Chemistry. 2015(36): 7962-7983, 2015.

Hřebabecký H., Procházková E., Šála M., Plačková P., Tloušťová E., Barauskas O., Lee Y. J., Tian Y., Mackman R., Nencka R.:
Synthesis and biological evaluation of conformationally restricted adenine bicycloribonucleosides.
Organic & Biomolecular Chemistry. 13(35): 9300-9313, 2015.

Mejdrová I., Chalupská D., Kögler M., Šála M., Plačková P., Bäumlová A., Hřebabecký H., Procházková E., Dejmek M., Guillon R., Strunin D., Weber J., Lee G., Birkuš G., Mertlíková-Kaiserová H., Bouřa E., Nencka R.:
Highly Selective Phosphatidylinositol 4-Kinase III beta Inhibitors and Structural Insight into Their Mode of Action.
Journal of Medicinal Chemistry. 58(9): 3767-3793, 2015.

Bildziukevich U., Vida N., Rárová L., Kolář M., Šaman D., Havlíček L., Drašar P., Wimmer Z.:
Polyamine derivatives of betulinic acid and beta-sitosterol: A comparative investigation.
Steroids. 100: 27-35, 2015.

Nonappa N., Šaman D., Kolehmainen E.:
Studies on supramolecular gel formation using DOSY NMR.
Magnetic Resonance in Chemistry. 53(4): 2560-260, 2015.

Sonawane M. R., Vávra J., Šaman D., Císařová I., Teplý F.:
Synthesis of Helquats Based on Phenanthridinium Units: Four-Step Procedure to Novel Extended Helical Dications.
Synthesis. 47(22): 3479-3488, 2015.

Šámal M., Chercheja S., Rybáček J., Vacek Chocholoušová J., Vacek J., Bednárová L., Šaman D., Stará I. G., Starý I.:
An Ultimate Stereocontrol in Asymmetric Synthesis of Optically Pure Fully Aromatic Helicenes.
Journal of the American Chemical Society. 137(26): 8469-8474, 2015.

Lachmanová Š., Dupeyre G., Tarábek J., Ochsenbein P., Perruchot Ch., Ciofini I., Hromadová M., Pospíšil L., Lainé P. P.:
Kinetics of Multielectron Transfers and Redox-Induced Structural Changes in N‑Aryl-Expanded Pyridiniums: Establishing Their Unusual, Versatile Electrophoric Activity.
Journal of the American Chemical Society. 137(35): 11349-11364, 2015.

Machová I., Snášel J., Dostál J., Brynda J., Fanfrlík J., Singh M., Tarábek J., Vaněk O., Bednárová L., Pichová I.:
Structural and Functional Studies of Phosphoenolpyruvate Carboxykinase from Mycobacterium tuberculosis.
PLoS ONE. 10(3): e0120682/1-e0120682/21, 2015.

Tarábek J., Kolivoška V., Gál M., Pospíšil L., Valášek M., Kaminský J., Hromadová M.:
Impact of the Extended 1,1'-Bipyridinium Structure on the Electron Transfer and pi-Dimer Formation. Spectroelectrochemical and Computational Study.
Journal of Physical Chemistry C. 119(32): 18056-18065, 2015.