2007

Bambuch V., Otmar M., Pohl R., Masojídková M., Holý A.:
C-Functionalization of 9-deazapurines by cross-coupling reactions.
Tetrahedron 7 (63): 1589-1601, 2007.

Wielgus-Kutrowska B., Antosiewicz J.M., Dlugosz M., Holý A., Bzowska A.:
Towards the mechanism of trimeric purine nucleoside phosphorylases: Stopped-flow studies of binding of multisubstrate analogue inhibitor-2-amino-9-[2-(phosphonomethoxy)ethyl]-6-sulfanylpurine.
Biophysical Chemistry 2-3 (125): 260-268, 2007.

Balzarini J., Schols D., Van Laethem K., De Clercq E., Hocková D., Masojídková M., Holý A.:
Pronounced in vitro and in vivo antiretroviral activity of 5-substituted 2,4-diamino-6-[2-(phosphonomethoxy)ethoxy] pyrimidines.
Journal of Antimicrobial Chemotherapy 1 (59): 80-86, 2007.

Duraffour S., Snoeck R., Krečmerová M., van Den Oord K., De Vos R., Holý A., Crance J.-M., Garin D., De Clercq. E., Andrei G.:
Activities of several classes of acyclic nucleoside phosphonates against camelpox virus replication in different cell culture models.
Antimicrobial Agents and Chemotherapy 51, 4410-4419, 2007.

Krečmerová M., Holý A. Pohl R., Masojídková M., Andrei G., Naesens L., Neyts J., Balzarini J., De Clercq E., Snoeck R.:
Ester prodrugs of cyclic 1-(S)-[3-hydroxy-2-(phosphonomethoxy)propyl]-5-azacytosine: Synthesis and antiviral activity.
Journal of Medicinal Chemistry 50, 5765-5772, 2007.

Krečmerová M., Holý A., Pískala A., Masojídková M., Andrei G., Naesens L., Neyts J., Balzarini J., De Clercq E., Snoeck R.:
Antiviral activity of triazine analogues of 1-(S)-[3-hydroxy-2-(phosphonomethoxy)propyl]cytosine (cidofovir) and related compounds.
Journal of Medicinal Chemistry 50, 1069-1077, 2007.

Renders M., Emmerechts G., Rozenski J., Krečmerová M., Holý A., Herdewijn P.:
Enzymatic synthesis of phosphonomethyl oligonucleotides by therminator polymerase.
Angewandte Chemie International Edition 46, 2501-2504, 2007.

Lebeau I., Andrei G., Krečmerová M., De Clercq E., Holý A., Snoeck R.:
Inhibitory activity of three classes of acyclic nucleoside phosphonates against murine polyomavirus and primate SV 40 strains.
Antimicrobial Agents and Chemotherapy 51, 2268-2273, 2007.

Krečmerová M., Holý A., Masojídková M.:
Pyrimidine acyclic nucleotide analogues with aromatic substituents in C-5 position.
Collection of Czechoslovak Chemical Communications 72, 927-951, 2007.

Doláková P., Masojídková M., Holý A.:
Efficient Synthesis of Pyrimidinecarbonitriles and Their Derivatives.
Heterocycles 71, 1107-1115, 2007.

Vrbková S., Dračínský M., Holý A.:
Bifunctional acyclic nucleoside phosphonates: synthesis of chiral 9-{3-hydroxy[1,4-bis(phosphonomethoxy)]butan-2-yl} derivatives of purines.
Tetrahedron: Asymmetry 18, 2233-2247, 2007.

Kmoníčková E., Melkusová P., Farghali H., Holý A., Zídek Z.:
Nitric oxide production in mouse and rat macrophages: A rapid and efficient assay for screening of drugs immunostimulatory effects in human cells.
Nitric Oxide: Biology and Chemistry 17, 160-169, 2007.

Zídek Z., Kmoníčková E., Holý A.:
Secretion of antiretroviral chemokines by human cells cultured with acyclic nucleoside phosphonates.
European Journal of Pharmacology 574, 77-84, 2007.

Pomeisl K., Holý A., Pohl R.:
Pd-catalyzed Suzuki-Miyaura coupling reactions in the synthesis of 5-aryl-1-[2-(phosphonomethoxy)ethyl]uracils as potencial multisubstrate inhibitors of thymidine phosphorylase.
Tetrahedron Letters 48, 3065-3067, 2007.

Nencka R., Votruba I., Hřebabecký H., Jansa P., Tloušt'ová E., Horská K., Masojídková M, Holý A.:
Discovery of 5-Substituted-6-chlorouracils as Efficient Inhibitors of Human Thymidine Phosphorylase.
Journal of Medicinal Chemistry 50, 6016-6023, 2007.

Hřebabecký H., Dračínský M., Holý A.:
Synthesis of Novel Carbocyclic Nucleosides and Pro-Tides Derived from 4-Oxatricyclo[4.2.1.03,7]nonane-9-methanol.
Collection of Czechoslovak Chemical Communications 72, 1331-1349, 2007.

Zápotocký M., Hanzalová J., Starková J., Votruba I., Holý A., Otová B.:
Experimental Therapy with 9-[2-(Phosphonomethoxy)ethyl]-2,6-diaminopurine (PMEDAP): Origin of Resistence.
Folia Biologica 53, 79-84, 2007.