2007

Bařinka C., Starková J, Konvalinka J., Lubkowski J.:
A high-resolution structure of ligand-free human glutamate carboxypeptidase II.
Acta Crystallographica Section F: Structural Biology and Crystallization Communications 63: 150-153, 2007.

Hlouchová K., Bařinka C., Klusák V., Šácha P., Mlčochová P., Majer P., Rulíšek L., Konvalinka J.:
Biochemical characterization of human glutamate carboxypeptidase III.
Journal of Neurochemistry 101 (3): 682-696, 2007.

Nijhuis M., van Maarseveen NM., Lastere S., Schipper P., Coakley E., Glass B., Rovenská M., de Jong D., Chappey C., Goedegebuure IW., Heilek-Snyder G., Dulude D., Cammack N., Brakier-Gingras L., Konvalinka J., Parkin N., Kräusslich HG., Brun-Vezinet F., Boucher CA.:
A Novel Substrate-Based HIV-1 Protease Inhibitor Drug Resistance Mechanism.
PLoS Medicine 1 (4): e36, 2007.

Šácha P., Zámečník J., Bařinka C., Hlouchová K., Vícha A., Mlčochová P., Hilgert I., Eckschlager T., Konvalinka J.:
Expression of glutamate carboxypeptidase II in human brain.
Neuroscience 4 (144): 1361-1372, 2007.

Kožíšek M., Bray J., Řezáčová P., Šašková K., Brynda J., Pokorná J., Mammano F., Rulíšek L., Konvalinka J.:
Molecular analysis of the HIV-1 resistance development: enzymatic activities, crystal structures, and thermodynamics of nelfinavir-resistant HIV protease mutants.
Journal of Molecular Biology 374 (4): 1005-16, 2007.

Mlčochová P., Plechanovová A., Bařinka C., Mahadevan D., Saldanha J.W., Rulíšek L., Konvalinka J.:
Mapping of the active site of glutamate carboxypeptidase II by site-directed mutagenesis.
FEBS Journal 274 (18): 4731-41, 2007.

Bařinka C., Rovenská M., Mlčochová P., Hlouchová K., Plechanovová A., Majer P., Tsukamoto T., Slusher B.S., Konvalinka J., Lubkowski J.:
Structural insight into the pharmacophore pocket of human glutamate carboxypeptidase II.
Journal of Medicinal Chemistry 50 (14): 3267-73, 2007.