2008

Hoffman H.E., Jirásková J., Ingr M., Zvelebil M., Konvalinka J.:
Recombinant human serine racemase: Enzymologic characterization and comparison with its mouse ortholog.
Protein Expression and Purification (Epub ahead of print), 2008.

Kožíšek M., Cígler P., Lepšík M., Fanfrlík J., Řezáčová P., Brynda J., Pokorná J., Plesek J., Grüner B., Grantz Šašková K., Václavíková J., Král V., Konvalinka J.:
Inorganic polyhedral metallacarborane inhibitors of HIV protease: a new approach to overcoming antiviral resistance.
Journal of Medicinal Chemistry 51 (15): 4839-43, 2008.

Grantz Šašková K., Kožíšek M., Lepšík M., Brynda J., Řezáčová P., Václavíková J., Kagan R.M., Machala L., Konvalinka J.:
Enzymatic and structural analysis of the I47A mutation contributing to the reduced susceptibility to HIV protease inhibitor lopinavir.
Protein Science 17 (9): 1555-64, 2008.

Kožíšek M., Grantz Šašková K., Řezáčová P., Brynda J., van Maarseveen N.M., De Jong D., Boucher C.A., Kagan R.M., Nijhuis M., Konvalinka J.:
Ninety-nine is not enough: molecular characterization of inhibitor-resistant human immunodeficiency virus type 1 protease mutants with insertions in the flap region.
Journal of Virology 82 (12): 5869-78, 2008.

Bartoňová V., Král V., Sieglová I., Brynda J., Fábry M., Hořejší M., Kožíšek M., Grantz Šašková K., Konvalinka J., Sedláček J., Řezáčová P.:
Potent inhibition of drug-resistant HIV protease variants by monoclonal antibodies.
Antiviral Research 78 (3): 275-7, 2008.

Cígler P., Král V., Kožíšek M., Konvalinka J., Mirský V.M.:
Anomalous adsorptive properties of HIV protease: indication of two-dimensional crystallization?
Colloids and Surfaces. B, Biointerfaces 64 (1):145-9, 2008.

Bařinka C., Hlouchová K., Rovenská M., Majer P., Dauter M., Hin N., Ko Y.S., Tsukamoto T., Slusher BS., Konvalinka J., Lubkowski J.:
Structural basis of interactions between human glutamate carboxypeptidase II and its substrate analogs.
Journal of Molecular Biology 376 (5): 1438-50, 2008.

Rovenská M., Hlouchová K., Šácha P., Mlčochová P., Horák V., Zámečník J., Bařinka C., Konvalinka J.:
Tissue expression and enzymologic characterization of human prostate specific membrane antigen and its rat and pig orthologs.
The Prostate. 68 (2): 171-82, 2008.