People

Name Maletínská Lenka
Position Head of the Senior Research Group
Dr. Lenka Maletínská

Lenka Maletínská, Ph.D.

Head of the Senior Research Group


Antiobesity peptides
Institute of Organic Chemistry and Biochemistry ASCR, v.v.i.
Flemingovo nám. 2, CZ-166 10 Prague 6, Czech Republic

☎: (+420) 220 183 567
℻: (+420) 220 183 571

 
Education
1989-1993 Ph.D. in Biochemistry, at Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic, Prague.
1983-1988 M.Sc. in Biochemistry, at Charles University, Faculty of Natural Sciences, Prague.
 
Experience
1998-1999 Postdoctoral research associate, Lawrence Berkeley National Laboratory, Berkeley, California, U.S.A., Dr. T. Forte.
1994-1996 Postdoctoral research associate, Dept. Pharmacology, University of Sherbrooke, Canada, Prof. E. Escher.
1991 (4 months) Fellowship, Centre CNRS-INSERM de Pharmacologie et Endocrinologie, Montpellier, France, Prof. J. Martinez.
1990 (1 month) Fellowship, Institute of Organic Synthesis, Riga, Latvia, Prof.V.Kluša
 
Appointments
since 2016 Head of the senior research group Antiobesity peptides, Institute of Organic Chemistry and Biochemistry v.v.i., Academy of Sciences of the Czech Republic, Prague.
2013-2015 Head of the targeted research team Antiobesity peptides, Institute of Organic Chemistry and Biochemistry v.v.i., Academy of Sciences of the Czech Republic, Prague.
2007-2012 Scientist, Jiracek's group, Institute of Organic Chemistry and Biochemistry v.v.i., Academy of Sciences of the Czech Republic, Prague.
2003-2006 Scientist, Biological Chemistry Department, Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic, Prague.
2001-2003 Maternity Leave.
since 1993 Researcher, Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic, Prague.
 
Other Experience and Professional Memberships
since 1996 Member of European Peptide Society.
since 2007 Member of American Peptide Society.
 
Research interest
  • Structure-activity studies of peptides (cholecystokinin analogues, CART peptides) with special emphasis on their anorectic activity after central and peripheral administration; binding affinities, in vitro and in vivo functional assays.
  • Study of food intake regulation in mouse models of obesity.
  • Ligand binding and signal transduction in cultured cells (study of LDL receptor, putative CART receptor in neuronal cell cultures).