Organic Chemistry

Tutor	Mgr. Radim Nencka, Ph.D.
Team	Radim Nencka
Topic	Novel heterocyclic derivatives as lipid and protein kinase inhibitors
Faculty	FPBT VŠCHT / PřF UK
Abstract	Lipid and protein kinases represent important molecular targets for advanced therapeutics with a wide range of indications. The project is based on our recent discovery of novel inhibitors with significant activity against several lipid kinases that may serve as potential therapeutics against various types of solid tumors, but also may find application in the treatment of various viral or neurodegenerative diseases.