2006
Nekvindová J., Mašek V., Veinlichová A., Anzenbacherova E., Anzenbacher P., Zídek Z., Holý A.:
Inhibition of human liver microsomal cytochrome P450 activities by adefovir and tenofovir.
Xenobiotica 12 (36): 1165-1177, 2006.
Hořejší K., Andrei G., Clercq E.D., Snoeck R., Pohl R., Holý A.:
Tricyclic etheno analogs of PMEG and PMEDAP: Synthesis and biological activity.
Bioorganic and Medicinal Chemistry 23 (14): 8057-8065, 2006.
Holý A.:
Antiviral acyclic nucleoside phosphonates structure activity studies.
Antiviral Research 2-3 SPEC. ISS. (71): 248-253, 2006.
Česnek M., Masojídková M., Holý A., Solinova V., Koval D., Kašička V.:
Synthesis and properties of 2-guanidinopurines.
Collection of Czechoslovak Chemical Communications 9 (71): 1303-1319, 2006.
Pechar M., Braunová A., Subr V., Ulbrich K., Holý A.:
Polymeric conjugates of 9-[2-(phosphonomethoxy)ethyl]purine with potential antiviral and cytostatic activity.
Collection of Czechoslovak Chemical Communications 8 (71): 1211-1220, 2006.
Potměšil P., Krečmerová M., Kmoničková E., Holý A., Zídek Z.:
Nucleotide analogues with immunobiological properties: 9-[2-Hydroxy-3-(phosphonomethoxy)propyl]-adenine (HPMPA), -2,6-diaminopurine (HPMPDAP), and their N6-substituted derivatives.
European Journal of Pharmacology 1-3 (540): 191-199, 2006.
Hřebabecký H., Masojídková M., Dračínský M., Holý A.:
Synthesis of novel conformationally locked carbocyclic nucleosides derived from 3-(hydroxymethyl)bicyclo[2.2.1]heptane-2,5-diol.
Collection of Czechoslovak Chemical Communications 6 (71): 871-888, 2006.
Šála M., Hřebabecký H., Masojídková M., Holý A.:
Synthesis of novel racemic conformationally locked carbocyclic nucleosides derived from 7-substituted bicyclo[2.2.1]hept-5-ene-2,2-dimethanols.
Collection of Czechoslovak Chemical Communications 5 (71): 635-649, 2006.
Zídek Z., Anzenbacher P., Anzenbacherova E., Buchar E., Kmoničková E., Potměšil P., Holý A.:
In vivo effects of antiviral acyclic nucleoside phosphonate 9-[2-(phosphonomethoxy)ethyl]adenine (adefovir) on cytochrome P450 system of rat liver microsomes.
Journal of Biomedical Science 3 (13): 295-301, 2006.
Schinkmanová M., Votruba I., Holý A.:
N6-Methyl-AMP aminohydrolase activates N6-substituted purine acyclic nucleoside phosphonates.
Biochemical Pharmacology 9 (71): 1370-1376, 2006.
Pomeisl K., Votruba I., Holý A., Pohl R.:
Syntheses of base and side-chain modified pyrimidine 1-[2- (phosphonomethoxy)propyl] derivatives as potent inhibitors of thymidine phosphorylase (PD-ECGF) from SD-lymphoma.
Collection of Czechoslovak Chemical Communications 4 (71): 595-624, 2006.
Vrbovská S., Holý A., Pohl R., Masojídková M.:
Bifunctional acyclic nucleoside phosphonates. 1. Symmetrical 1,3-bis[(phosphonomethoxy)propan-2-yl] derivatives of purines and pyrimidines.
Collection of Czechoslovak Chemical Communications 4 (71): 543-566, 2006.
Krečmerová M., Masojídková M., Holý A.:
Preparation of C-5 substituted cidofovir derivatives.
Collection of Czechoslovak Chemical Communications 4 (71): 579-594, 2006.
Šolínová V., Kašička V., Koval D., Česnek M., Holý A.:
Determination of acid-base dissociation constants of amino- and guanidinopurine nucleotide analogs and related compounds by capillary zone electrophoresis.
Electrophoresis 5-6 (27): 1006-1019, 2006.
Nencka R., Votruba I., Hřebabecký H., Tloušťová E., Horská K., Masojídková M., Holý A.:
Design and synthesis of novel 5,6-disubstituted uracil derivatives as potent inhibitors of thymidine phosphorylase.
Bioorganic and Medicinal Chemistry Letters 5 (16): 1335-1337, 2006.
Stittelaar K.J., Neyts J., Naesens L., Van Amerongen G., Van Lavieren R.F., Holý A., De Clercq E., Niesters H.G.M., Fries E., Maas C., Mulder P.G.H., Van Der Zeijst B.A.M., Osterhaus A.D.M.E.:
Antiviral treatment is more effective than smallpox vaccination upon lethal monkeypox virus infection.
Nature 7077 (439): 745-748, 2006.
Kmoničková E., Potměšil P., Holý A., Zídek Z.:
Purine P1 receptor-dependent immunostimulatory effects of antiviral acyclic analogues of adenine and 2,6-diaminopurine.
European Journal of Pharmacology 1-2 (530): 179-187, 2006.
Hořejší K., Pohl R., Holý A.:
Tricyclic purine analogs derived from 2-amino-6-chloropurine and 2,6-diaminopurine and their methylated quaternary salts.
Collection of Czechoslovak Chemical Communications 1 (71): 77-90, 2006.
Horská K., Votruba I., Holý A.:
Interaction of phosphates of the acyclic nucleoside phosphonates with nucleoside diphosphate kinase from yeast and bovine liver.
Collection of Czechoslovak Chemical Communications 1 (71): 35-43, 2006.