INSTITUTE OF PHYSIOLOGY CAS

Structural motifs within the TRPA1 receptor contribute to detection of painful stimuli Acute pain is a normal reaction of the somatosensory system to noxious stimulation which serves a protective function and is the first symptom of disease, especially of inflammatory origin. In its chronic form, pain is maladaptive and has a significant impact on quality of life. The scientists from the Department of Cellular Neurophysiology investigate the function of a distinct group of proteins involved in the mechanisms of acute and chronic pain.

Anti-inflammatory effects of omega-3 PUFA are mediated by new lipid mediators from adipose tissue Chronic low-grade inflammation contributes to the development of diabetes, as well as cardiovascular, gastrointestinal and certain brain disorders. Lipids of marine origin help to prevent inflammatory diseases.

Why some people have dental caries? Research of dental caries follow up the scientists of Department Analysis of Biologically Important Compounds of Institute of Physiology and specialists of School of Medical Dentistry, 1st Medical Faculty of Charles University.