News

Den otevřených dveří 4. 11. 2016

International Conference on Cell Biology and Radiobiology

The International Conference on Cell Biology and Radiobiology is being organized by the Institute of Biophysics, v.v.i., in Brno in 8th – 10th September 2016.

New publications

Post-Translational Modifications of Histones in Human Sperm

Krejci, J., Stixova, L., Pagacova, E., Legartova, S., Kozubek, S., Lochmanova, G., Zdrahal, Z., Sehnalova, P., Dabravolski, S., Hejatko, J., Bartova, E.

Three TERT genes in Nicotiana tabacum

Sykorova, E., Fulneckova, J., Mokros, P., Fajkus, J., Fojtova, M., Peska, V.

Antitumor platinum(IV) derivatives of oxaliplatin with axial valproato ligands

Novohradsky, V., Zerzankova, L., Stepankova, J., Vrana, O., Raveendran, R., Gibson, D., Kasparkova, J., Brabec, V.

Noncanonical Hydrogen Bonding in Nucleic Acids. Benchmark Evaluation of Key Base-Phosphate Interactions in Folded RNA Molecules Using Quantum-Chemical Calculations and Molecular Dynamics Simulations

Zgarbova, M., Jurecka, P., Banas, P., Otyepka, M., Sponer, JE., Leontis, NB., Zirbel, CL., Sponer, J.

Expression of 5 S rRNA genes linked to 35 S rDNA in plants, their epigenetic modification and regulatory element divergence

Garcia, S., Khaitova, LC., Kovarik, A.
Further publications

Selected results

Detecting DNA damage and monitoring of enzymatic DNA processing by electrochemical methods

Electrochemical approaches have been applied to detect specific nucleobase lesions and to design fast techniques for the monitoring of DNA-processing enzymes activity.

Osmium tetroxide, 2,2'-bipyridine (Os,bipy): Electroactive marker for probing accessibility of tryptophan residues in proteins.

Os,bipy forms at physiological conditions electroactive covalent adducts with tryptophan residues. 

Unfolding/denaturation and aggregation of proteins viewed by electrochemical methods

Pioneering work of the group headed by prof. E. Paleček in the field of electrochemical analysis of proteins based on their electrocatalytic activity giving rise to “peak H”.

Komplexy šestimocného osmia jako nástroje pro specifické značení cukerných zbytků v biopolymerech

In the area of electroactive labeling of natural polysaccharides this work opens new possibilities for the analysis of glycoproteins or other biomolecules possessing sugar moieties.

Fagocyty ve zdraví a nemoci

Fagocyty (neutrofily, monocyty, makrofágy) jsou nezastupitelnými buňkami první obranné linie, chránicími tělo před invadujícími mikrobiálními patogeny. 

Further results