2012

Schimer J., Cígler P., Veselý J., Šašková K., Lepšík M., Brynda J., Řezáčová P., Kožíšek M., Císařová I., Oberwinkler H., Kraeusslich H.G., Konvalinka J.:
Structure-Aided Design of Novel Inhibitors of HIV Protease Based on a Benzodiazepine Scaffold.
Journal of Medicinal Chemistry 55: 10130-10135, 2012.

Veverka V., Baker T., Redpath N.T., Carrington B., Muskett F.W., Taylor R.J., Lawson A.D.G., Henry A.J., Carr M.D.:
Conservation of Functional Sites on Interleukin-6 and Implications for Evolution of Signaling Complex Assembly and Therapeutic Intervention.
Journal of Biological Chemistry 287: 40043-40050, 2012.

Tratsiak K., Chaloupková R., Řezáčová P., Damborský J., Smatanova I.K.:
Characterization of a novel haloalkane dehalogenase DmxA from Marinobacter sp ELB 17.
FEBS Journal 279: 427-427, 2012.

Gerstorferová D., Weignerová L., Mader P., Brynda J., Řezáčová P., Křen V.:
Fungal alpha-L-rhamnosidase - properties and crystallization.
FEBS Journal 279: 247-247, 2012.

Holdsworth G., Slocombe P., Doyle C., Sweeney B., Veverka V., Le Riche K., Franklin R.J., Compson J., Brookings D., Turner J., Kennedy J., Garlish R., Shi J.Y., Newnham L., McMillan D., Muzylak M., Carr M.D., Henry A.J., Ceska T., Robinson M.K.:
Characterization of the Interaction of Sclerostin with the Low Density Lipoprotein Receptor-related Protein (LRP) Family of Wnt Co-receptors.
Journal of Biological Chemistry 287: 26464-26477, 2012.

Raindlová V., Pohl R., Klepetářová B., Havran L., Šimková E., Horáková P., Pivoňková H., Fojta M., Hocek M.:
Synthesis of Hydrazone-Modified Nucleotides and Their Polymerase Incorporation onto DNA for Redox Labeling.
ChemPlusChem 77: 652-662, 2012.

Kožíšek M., Henke S., Šaškova K., Jacobs G.B., Schuch A., Buchholz B., Muller V., Krausslich H.G., Řezáčová P., Konvalinka J., Bodem J.:
Mutations in HIV-1 gag and pol Compensate for the Loss of Viral Fitness Caused by a Highly Mutated Protease.
Antimicrobial Agents and Chemotherapy 56: 4320-4330, 2012.

Illingworth C.J.R., Chintipalli S.V., Serapian S.A., Miller A.D., Veverka V., Carr M.D., and Reynolds C.A.:
The Statistical Significance of Selected Sense-Antisense Peptide Interactions.
Journal of Computational Chemistry 33: 1440-1447, 2012.

Černová M., Pohl R., Klepetářová B., Hocek M.:
A General Regioselective Synthesis of 2,4-Diarylpyrimidines from 2-Thiouracil through Two Orthogonal Cross-Coupling Reactions.
Synlett 1305-1308, 2012.

Chernykh Y., Opekar S., Klepetářová B., Beier P.:
Application of PhSCF2CF2SiMe3 as a Tandem Anion and Radical Tetrafluoroethylene Equivalent: Fluoride-Catalyzed Addition to N-Substituted Cyclic Imides Followed by Radical Cyclization.
Synlett 1187-1190, 2012.

Gitto R., Damiano F.M., Mader P., De Luca L., Ferro S., Supuran C.T., Vullo D., Brynda J., Řezáčová P., Chimirri A.:
Synthesis, Structure-Activity Relationship Studies, and X-ray Crystallographic Analysis of Arylsulfonamides as Potent Carbonic Anhydrase Inhibitors.
Journal of Medicinal Chemistry 55: 3891-3899, 2012.

Marek A., Patil M.R., Klepetářová B., Kohout L., Elbert T.:
A stereospecific pathway for the introduction of deuterium on the brassinosteroid skeleton by reductive dechlorination of chlorocarbonates.
Tetrahedron Letters 53: 2048-2050, 2012.

Zítková M., Juřeníková P., Špačková J., Řezáčová P.:
Aspects of adaptation process in haemato-oncology.
Bone Marrow Transplantation 47: S494-S494, 2012.

Procházková K., Čermáková K., Pachl P., Sieglová I., Fabry M., Otwinowski Z., Řezáčová P.:
Structure of the effector-binding domain of the arabinose repressor AraR from Bacillus subtilis.
Acta Crystallographica D 68: 176-185, 2012.

Dostál J., Brynda J., Hrušková-Heidingsfeldová O., Pachl P., Pichová I., Řezáčová P.:
The crystal structure of protease Sapp1p from Candida parapsilosis in complex with the HIV protease inhibitor ritonavir.
Journal of Enzyme Inhibition and Medicinal Chemistry 27: 160-165, 2012.

Jansa P., Hradil O., Baszczynski O., Dračínský M., Klepetářová B., Holý A., Balzarini J., Janeba Z.:
An efficient microwave-assisted synthesis and biological properties of polysubstituted pyrimidinyl- and 1,3,5-triazinylphosphonic acids.
Tetrahedron 68: 865-871, 2012.

Sedláček J., Fabry M., Sieglová I., Král V., Uhnaková B., Mudra M., Kronrad L., Sawicka A., Mikolajczak R., Řezáčová P.:
Recombinant fragment of an antibody tailored for direct radioiodination.
Journal of Labelled Compounds and Radiopharmaceuticals 55: 52-56, 2012.

Oka O., Waters L.C., Strong S.L., Dosanjh N.S., Veverka V., Muskett F.W., Renshaw P.S., Klempnauer K.H., Carr M.D.:
Interaction of the Transactivation Domain of B-Myb with the TAZ2 Domain of the Coactivator p300: Molecular Features and Properties of the Complex.
PloS one 7: e52906, 2012.